Phase 2 HIV Clinical Trials
62 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 62 trials
Recruiting
Phase 2
Imaging and Biopsy of People With HIV-1 Undergoing Analytic Treatment Interruption
HIV
National Cancer Institute (NCI)50 enrolled1 locationNCT05419024
Recruiting
Phase 1Phase 2
Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ...
Hematologic MalignanciesHIV
National Cancer Institute (NCI)265 enrolled1 locationNCT05470491
Recruiting
Phase 2
Effects of Cannabidiol and Tetrahydrocannabinol on Microbiome and Neuroinflammation in HIV
MicrobiomeHIVCannabis+3 more
University of California, San Diego90 enrolled1 locationNCT05514899
Recruiting
Phase 1Phase 2
Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission
HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)1,120 enrolled46 locationsNCT02140255
Recruiting
Phase 2
Doravirine (DOR) in Human Immunodeficiency Virus (HIV)-Infected Children Aged 4 Weeks to <12 Years and <45 kg (MK-1439-066)
Human Immunodeficiency Virus (HIV) Infection
Merck Sharp & Dohme LLC84 enrolled24 locationsNCT04375800
Recruiting
Phase 2
Evaluation of Long-Acting Lenacapavir for the Treatment of HIV-1 in Treatment-experienced Adolescents and Children
HIV-1-infection
Gilead Sciences12 enrolled9 locationsNCT06749054
Recruiting
Phase 2
GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV
HIVAlcohol
Vanderbilt University Medical Center200 enrolled1 locationNCT07221214
Recruiting
Phase 2Phase 3
A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Merck Sharp & Dohme LLC570 enrolled47 locationsNCT07266831
Recruiting
Phase 2
A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission
Acute HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)48 enrolled36 locationsNCT05719441
Recruiting
Phase 1Phase 2
Study of Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in Virologically Suppressed Children Living With HIV-1, Two to Less Than 12 Years of Age
HIV-1-infection
National Institute of Allergy and Infectious Diseases (NIAID)90 enrolled12 locationsNCT05660980
Recruiting
Phase 1Phase 2
Exploratory Study of LP-98 for Injection in ART-Naive HIV-Infected Individuals
HIV
Shanxi Kangbao Biological Product Co., Ltd.30 enrolled1 locationNCT07433387
Recruiting
Phase 2
A Study of VRC07-523LS, PGT121.414.LS, and PGDM1400LS Broadly Neutralizing Monoclonal Antibodies Given Intravenously in Adult Participants Without HIV
HIV
National Institute of Allergy and Infectious Diseases (NIAID)200 enrolled22 locationsNCT06812494
Recruiting
Phase 1Phase 2
CAR-T Cells for HIV Infection
HIV Infections
Steven Deeks18 enrolled2 locationsNCT04648046
Recruiting
Phase 2
Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer
HIV InfectionAnal Squamous Cell CarcinomaStage II Rectal Cancer AJCC v8+7 more
National Cancer Institute (NCI)40 enrolled14 locationsNCT04929028
Recruiting
Phase 2
Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV
Mild Neurocognitive DisorderMajor Depressive DisorderHIV
National Institute of Allergy and Infectious Diseases (NIAID)186 enrolled40 locationsNCT06705478
Recruiting
Phase 2
Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide
HIVAlcohol Use Disorder (AUD)
Yale University30 enrolled1 locationNCT07040592
Recruiting
Phase 2
A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)
HIV Infections
ViiV Healthcare150 enrolled62 locationsNCT07202546
Recruiting
Phase 2
Evaluating the Safety and Immunogenicity of MTBVAC
TuberculosisHIV I Infection
HIV Vaccine Trials Network276 enrolled16 locationsNCT05947890
Recruiting
Phase 2
A Clinical Trial of STP0404 in Adults With HIV-1 Infection
HIV-1-infection
ST Pharm Co., Ltd.36 enrolled13 locationsNCT05869643
Recruiting
Phase 2
Improving Physical Ability and Cellular Senescence Elimination in HIV
FrailtyHIVAging Problems+1 more
National Institute of Allergy and Infectious Diseases (NIAID)80 enrolled27 locationsNCT07144293