Phase 2 HIV Clinical Trials

74 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 74 trials

Recruiting
Phase 1Phase 2

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)1,120 enrolled46 locationsNCT02140255
Recruiting
Phase 2

Targeted Therapies for Immunological Non-Responders in People With HIV: A Multicenter Clinical Study

Immunological Non-Responders in People With HIV
Beijing 302 Hospital21 enrolled5 locationsNCT07637877
Recruiting
Phase 2

Imaging and Biopsy of People With HIV-1 Undergoing Analytic Treatment Interruption

HIV
National Cancer Institute (NCI)50 enrolled1 locationNCT05419024
Recruiting
Phase 2

Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV

Mild Neurocognitive DisorderMajor Depressive DisorderHIV
National Institute of Allergy and Infectious Diseases (NIAID)186 enrolled41 locationsNCT06705478
Recruiting
Phase 2

Boosting Olfactory and Sensory Training Study (BOOST)

HIV (Human Immunodeficiency Virus)
University of Alabama at Birmingham80 enrolled1 locationNCT07221123
Recruiting
Phase 1Phase 2

Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

HIV-1-infection
National Institute of Allergy and Infectious Diseases (NIAID)36 enrolled12 locationsNCT06071767
Recruiting
Phase 2Phase 3

Evaluating Smoking Cessation Interventions for PWH in South Africa

Comorbidities and Coexisting ConditionsSmoking CessationHIV
Johns Hopkins University660 enrolled1 locationNCT05413122
Recruiting
Phase 1Phase 2

Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ...

Hematologic MalignanciesHIV
National Cancer Institute (NCI)265 enrolled1 locationNCT05470491
Recruiting
Phase 2Phase 3

A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)

Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Merck Sharp & Dohme LLC570 enrolled56 locationsNCT07266831
Recruiting
Phase 1Phase 2

The Tatelo Plus Study

HIV InfectionsHIV
National Institute of Allergy and Infectious Diseases (NIAID)41 enrolled2 locationsNCT06508749
Recruiting
Phase 2

Inflammation and Depression in People With HIV

DepressionAnhedoniaHIV
Emory University60 enrolled2 locationsNCT05849038
Recruiting
Phase 2

GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV

Cardiovascular Disease PreventionSmoking, CigaretteHIV+1 more
Vanderbilt University Medical Center200 enrolled1 locationNCT07221214
Recruiting
Phase 2

Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV

Obesity and OverweightHIVChronic Inflammation
University of Hawaii12 enrolled1 locationNCT06935838
Recruiting
Phase 1Phase 2

Study of Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in Virologically Suppressed Children Living With HIV-1, Two to Less Than 12 Years of Age

HIV-1-infection
National Institute of Allergy and Infectious Diseases (NIAID)90 enrolled12 locationsNCT05660980
Recruiting
Phase 2

Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

FrailtyAgingHIV-1-infection+2 more
Massachusetts General Hospital100 enrolled2 locationsNCT06554717
Recruiting
Phase 1Phase 2

A Study to Investigate Cabotegravir for Neonates Exposed to HIV-1

HIV Infections
ViiV Healthcare44 enrolled1 locationNCT07275606
Recruiting
Phase 2

A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)

HIV Infections
ViiV Healthcare150 enrolled113 locationsNCT07202546
Recruiting
Phase 1Phase 2

Exploratory Study of LP-98 for Injection in ART-Naive HIV-Infected Individuals

HIV
Shanxi Kangbao Biological Product Co., Ltd.30 enrolled1 locationNCT07433387
Recruiting
Phase 2

A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV

HIV (Human Immunodeficiency Virus)MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Naga P. Chalasani120 enrolled10 locationsNCT07143968
Recruiting
Phase 2

Effects of Cannabidiol and Tetrahydrocannabinol on Microbiome and Neuroinflammation in HIV

MicrobiomeHIVCannabis+3 more
University of California, San Diego90 enrolled1 locationNCT05514899