Phase 3 HIV Clinical Trials
23 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 23 trials
Recruiting
Phase 3
A Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-010)
Human Immunodeficiency Virus (HIV)HIV Pre-Exposure Prophylaxis
Merck Sharp & Dohme LLC4,580 enrolled27 locationsNCT07071623
Recruiting
Phase 3
A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1
HIV Infections
ViiV Healthcare332 enrolled89 locationsNCT06694805
Recruiting
Phase 3
A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)
Human Immunodeficiency Virus (HIV)HIV Pre-Exposure Prophylaxis
Merck Sharp & Dohme LLC4,390 enrolled70 locationsNCT07044297
Recruiting
Phase 3
Study of Lenacapavir as a Once-Yearly Injection for HIV Pre-exposure Prophylaxis (PrEP)
HIV Pre-Exposure Prophylaxis
Gilead Sciences350 enrolled31 locationsNCT07047716
Recruiting
Phase 2Phase 3
A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Merck Sharp & Dohme LLC570 enrolled24 locationsNCT07266831
Recruiting
Phase 3
Low Dose Trimethoprim-Sulfamethoxazole for the Treatment of Pneumocystis Jirovecii Pneumonia
Pneumocystis PneumoniaPneumocystisPneumocystis Jirovecii Infection+5 more
Todd C. Lee MD MPH FIDSA416 enrolled1 locationNCT04851015
Recruiting
Phase 2Phase 3
Platform Trial For Cryptococcal Meningitis
HIVCryptococcal Meningitis
University of Minnesota2,000 enrolled2 locationsNCT06666322
Recruiting
Phase 3
Long-term Follow-up of Long-acting Cabotegravir (CAB LA) for PrEP (Pre-exposure Prophylaxis) in Participants at Risk of Acquiring HIV (Human Immunodeficiency Virus)
HIV Infections
ViiV Healthcare3,508 enrolled34 locationsNCT06134362
Recruiting
Phase 3
Optimizing Tobacco Use Treatment for PLWHA
Nicotine DependenceHIV/AIDS
University of Pennsylvania340 enrolled2 locationsNCT04176172
Recruiting
Phase 3
Dolutegravir/Lamivudine Dual Therapy for ART-naïve People With HIV and TB Receiving Rifampin-based TB Treatment
TuberculosisHIV
Johns Hopkins University150 enrolled6 locationsNCT06497465
Recruiting
Phase 3
Ndovu RCT: Investing the Optimal Management of Dolutegravir Resistance
HIV-1-infection
University of Nairobi392 enrolled9 locationsNCT06747507
Recruiting
Phase 3
Reducing Mortality in Adults With Advanced HIV Disease (REVIVE)
HIV Disease Progression
Population Health Research Institute8,000 enrolled52 locationsNCT05580666
Recruiting
Phase 3
DOR/TDF/3TC COmpared With BIC/FTC/TAF in ART-Naïve People Living With HIV and Overweight or Obesity
ObesityHIV (Human Immunodeficiency Virus)Overweight and/or Obesity
José Antonio Mata Marín306 enrolled1 locationNCT07075146
Recruiting
Phase 2Phase 3
Evaluating Smoking Cessation Interventions for PWH in South Africa
Comorbidities and Coexisting ConditionsSmoking CessationHIV
Johns Hopkins University660 enrolled1 locationNCT05413122
Recruiting
Phase 3
Efficacy, Acceptability and Safety of Event-driven HIV PrEP Using TAF/FTC in MSM in Thailand and France.
HIV/AIDS
ANRS, Emerging Infectious Diseases524 enrolled4 locationsNCT05813964
Recruiting
Phase 3
Antiretroviral Therapy for Acute and Chronic HIV Infection
Acute HIV InfectionChronic HIV Infection
SEARCH Research Foundation900 enrolled1 locationNCT00796263
Recruiting
Phase 3
SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder
HIV InfectionsSubstance UseAdherence, Treatment+1 more
Brigham and Women's Hospital40 enrolled1 locationNCT05378399
Recruiting
Phase 3
Testing a Real-time Electronic Antiretroviral Adherence Monitoring Intervention
HIV InfectionsAdherence, Medication
University of Illinois at Chicago126 enrolled1 locationNCT06550804
Recruiting
Phase 3
The Implementation of Pre-exposure Prophylaxis of Injectable Cabotegravir
HIV Infections
Evandro Chagas National Institute of Infectious Disease1,200 enrolled1 locationNCT05515770
Recruiting
Phase 3
Outcomes of the PLHIV With Suboptimal Viral Suppression to Injectable Long-acting Antiretrovirals
HIV-1-infectionNon-Adherence, Medication
Chang Gung Memorial Hospital40 enrolled4 locationsNCT06507059