Phase 4 HIV Clinical Trials

53 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 53 trials

Recruiting
Phase 4

Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP

Opioid-use DisorderHIV
University of Connecticut256 enrolled1 locationNCT05669534
Recruiting
Phase 4

A Study to Provide Continued Access to Study Drug to Children and Adolescents Who Have Completed Clinical Studies Involving Gilead HIV Treatments

HIV-1-infection
Gilead Sciences350 enrolled15 locationsNCT06337032
Recruiting
Phase 4

Post-Injectable Cabotegravir Antiretroviral Salvage Strategy Options Trial

HIV Prevention
University of Witwatersrand, South Africa100 enrolled3 locationsNCT06485154
Recruiting
Phase 4

Integrated e-Health (Electronic Health) for HIV and Substance Use Disorders in Justice Involved Women

Opioid-use DisorderHIVeHealth
Yale University250 enrolled2 locationsNCT05547048
Recruiting
Phase 4

Menopausal HT for Women Living With HIV (HoT)

MenopauseHIV Infection
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections105 enrolled23 locationsNCT06856174
Recruiting
Phase 4

UNCPM 22314 - Pregnancy, Infant and Maternal Health Outcomes Study

Pregnancy RelatedHIV PreventionPre-exposure Prophylaxis
University of North Carolina, Chapel Hill621 enrolled1 locationNCT06158126
Recruiting
Phase 4

Assessment of Metformin for Restoration of Immune Homeostasis in HIV+ and HIV- Individuals With a History of Injection Drug Use

Immune DysregulationHIVSystemic Inflammation+1 more
University of Alabama at Birmingham100 enrolled1 locationNCT06829238
Recruiting
Phase 4

Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care

Smoking CessationHuman Immunodeficiency Virus (HIV)
New York University500 enrolled1 locationNCT06598397
Recruiting
Phase 4

Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs

HIVSubstance Use Disorder (SUD)Injection Drug Use
Massachusetts General Hospital100 enrolled2 locationsNCT07199335
Recruiting
Phase 4

Doravirine Dose Optimisation in Pregnancy

HIV
University of Liverpool76 enrolled1 locationNCT05630638
Recruiting
Phase 4

OPTImizing Malaria And HIV Treatment in a Shifting Landscape in Africa

MalariaHIV
Yale University380 enrolled2 locationsNCT06967519
Recruiting
Phase 4

Enhancing PrEP Uptake and Retention Among Latine TGW and GBM in the South Using Long-Acting Injectable PrEP

HIV Prevention and CareHIV PreventionHIV Prevention Program+2 more
Duke University100 enrolled1 locationNCT07218211
Recruiting
Phase 4

MAPS PrEP Van Study

HIV Infection
Duke University20 enrolled1 locationNCT06908252
Recruiting
Phase 4

HIV Prevention With PrEP Among People on Opioid Replacement Therapy

HIV (Human Immunodeficiency Virus)
Cara Spence350 enrolled6 locationsNCT07160075
Recruiting
Phase 4

Implementation and Deliver of Lenacapavir for PrEP in a Community Pharmacy Setting

HIV
Kelley-Ross & Associates, Inc.75 enrolled1 locationNCT07210125
Recruiting
Phase 4

Zoledronic Acid for the Prevention of TDF-sparing ART-induced Bone Mass Density Loss in Treatment-naive HIV Positive Individuals

OsteopeniaHIV Infected Individuals
Hadassah Medical Organization110 enrolled3 locationsNCT06762730
Recruiting
Phase 4

Switch to Dolutegravir Plus Lamivudine Dual-Therapy in Transgender Women Living With HIV on Virologically Suppressive Antiretroviral Therapy (TRANS-SWITCH)

HIVHIV-1
UBATEC50 enrolled1 locationNCT06967753
Recruiting
Phase 4

Dexmedetomidine for Intraoperative Shivering in Scheduled Elective Cesarean Delivery

ShiveringDose Finding Study
Mayo Clinic40 enrolled1 locationNCT04730609
Recruiting
Phase 4

Comparative Study Between the Efficacy of Intravenous Hydrocortisone and Intravenous Dexmedetomidine for Prevention of Postoperative Shivering After General Anaesthesia for Abdominal Surgeries

Shivering
Ain Shams University70 enrolled1 locationNCT07154849
Recruiting
Phase 4

Efficacy, Safety, and ToLerability of Switching to A Two-Drug Regimen With DTG/3TC Compared to Maintaining A Three-Drug REgimen With BIC/FTC/TAF or DTG/3TC/ABC in ViroLogically SupprEssed PeopLe Living With HIV After 24 and 48 Weeks of Follow-Up

HIV Infections
José Antonio Mata Marín156 enrolled1 locationNCT07138144