Hypoglycemia Clinical Trials

10 recruiting

Frequently Asked Questions

Common questions about Hypoglycemia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 20 trials

Recruiting
Phase 3

A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

Diabetes Mellitus, Type 1Impaired Hypoglycemic AwarenessSevere Hypoglycemia
Vertex Pharmaceuticals Incorporated52 enrolled29 locationsNCT04786262
Recruiting
Phase 1Phase 2

A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

Metabolic DiseaseDiabetes Mellitus, Type 1Type 1 Diabetes+14 more
Otsuka Pharmaceutical Factory, Inc.13 enrolled1 locationNCT06575426
Recruiting

Diagnosing and Treating Low Blood Sugar Levels

InsulinomaHypoglycemia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1,500 enrolled1 locationNCT00001276
Recruiting
Early Phase 1

Effect of C-peptide on Hypoglycemic Counterregulation

Type 1 DiabetesHypoglycemia
University of Cincinnati38 enrolled1 locationNCT06470295
Recruiting

"Sexual Activity and Hypoglycemia Risk in Adults With Type 1 or Type 2 Diabetes Using Insulin Therapy and Continuous Glucose Monitoring"

Type 2 Diabetes (T2DM)HypoglycemiaType 1 Diabetes (T1D)
Medical University of Warsaw100 enrolled1 locationNCT07286500
Recruiting
Phase 2

A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes

Type 1 Diabetes Mellitus With Hypoglycemia
Zucara Therapeutics Inc.186 enrolled33 locationsNCT05762107
Recruiting

Precision Subclassification of Mental Health in Diabetes: Digital Twins for Precision Mental Health to Track Subgroups

Depression - Major Depressive DisorderAnorexia NervosaBulimia Nervosa+17 more
Forschungsinstitut der Diabetes Akademie Mergentheim1,809 enrolled3 locationsNCT07212075
Recruiting
Phase 1Phase 2

A Safety, Tolerability, and Efficacy Study of E-islet 01 in Participants With Type 1 Diabetes

Diabetes Mellitus, Type 1Impaired Hypoglycemic AwarenessSevere Hypoglycemia
EndoCell Therapeutics, Inc.21 enrolled1 locationNCT07126873
Recruiting
Phase 2

Restoration of Hypoglycemia Awareness With Metoclopramide

Hypoglycemia Unawareness
Simon Fisher36 enrolled2 locationsNCT03970720
Recruiting
Not Applicable

Personalized Hypoglycemia Outpatient Treatment - a Feasibility Study

Type 2 Diabetes (T2DM)Hypoglycemia (Diabetic)
Ottawa Hospital Research Institute120 enrolled1 locationNCT07094529
Recruiting
Early Phase 1

Regulation of Brain Glucose Metabolism in Type 1 Diabetes

Diabetes Mellitus, Type 1Hypoglycemia Unawareness
Yale University16 enrolled1 locationNCT05317455
Recruiting
Not Applicable

Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes

DementiaDiabetesHypoglycemia+1 more
Indiana University62 enrolled1 locationNCT05643144
Recruiting
Not Applicable

Safer Aging With Diabetes Monitoring

Diabetes Mellitus, Type 2Hypoglycemia
Kaiser Permanente360 enrolled4 locationsNCT06296485
Recruiting

A Study of Glycemic Control in Left Ventricular Assist

HyperglycemiaHypoglycemiaType 2 Diabetes Mellitus
Mayo Clinic20 enrolled1 locationNCT05933161
Recruiting
Not Applicable

Longitudinal Study of the GLUcagon REsponse to Hypoglycemia in Children and Adolescents With New-onset Type 1 DIAbetes

Type1diabetesSevere Hypoglycemia
Cliniques universitaires Saint-Luc- Université Catholique de Louvain1,000 enrolled1 locationNCT06770621
Recruiting
Not Applicable

Effect of Fasting on Hypoglycemic Counterregulation in Type 1 Diabetes

HypoglycemiaType1diabetes
University of Cincinnati10 enrolled1 locationNCT05973799
Recruiting

Glycemic Excursions in Patients With Type 1 Diabetes Mellitus Using Closed-loop Systems

Type 1 Diabetes MellitusType 1 Diabetes Mellitus With HypoglycemiaDrive
University Hospital, Motol120 enrolled1 locationNCT06382350
Recruiting
Not Applicable

Impact of MEnstruation on Glycemic Response and Exercise In Females With Type 1 Diabetes

Type 1 DiabetesHypoglycemiaHyperglycaemia Due to Type 1 Diabetes Mellitus+1 more
University of Colorado, Denver150 enrolled1 locationNCT06297980
Recruiting

French National Cohort of People With Type 1 Diabetes

Cardiovascular DiseasesPatient ParticipationDiabetes Mellitus, Type 1+1 more
Fondation Francophone pour la Recherche sur le Diabete15,000 enrolled1 locationNCT04657783
Recruiting
Not Applicable

Pilot Study Evaluating Safety of ExOlin® in Patients With Poorly Controlled Type 1 Diabetes

Type 1 DiabetesType 1 Diabetes Mellitus With Hypoglycemia
Defymed8 enrolled1 locationNCT05221359