Hypoglycemia Clinical Trials

21 recruiting

Hypoglycemia Trials at a Glance

45 actively recruiting trials for hypoglycemia are listed on ClinicalTrialsFinder across 6 cities in 18 countries. The largest study group is Not Applicable with 18 trials, with the heaviest enrollment activity in Indianapolis, Pittsburgh, and Baltimore. Lead sponsors running hypoglycemia studies include Indiana University, University of Cincinnati, and Cambridge University Hospitals NHS Foundation Trust.

Browse hypoglycemia trials by phase

Treatments under study

About Hypoglycemia Clinical Trials

Looking for clinical trials for Hypoglycemia? There are currently 21 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Hypoglycemia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Hypoglycemia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 45 trials

Recruiting

Diagnosing and Treating Low Blood Sugar Levels

InsulinomaHypoglycemia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1,500 enrolled1 locationNCT00001276
Recruiting
Phase 2

A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes

Type 1 Diabetes Mellitus With Hypoglycemia
Zucara Therapeutics Inc.186 enrolled46 locationsNCT05762107
Recruiting

A Study of Glycemic Control in Left Ventricular Assist

HyperglycemiaHypoglycemiaType 2 Diabetes Mellitus
Mayo Clinic20 enrolled1 locationNCT05933161
Recruiting
Phase 2

Restoration of Hypoglycemia Awareness With Metoclopramide

Hypoglycemia Unawareness
Simon Fisher36 enrolled2 locationsNCT03970720
Recruiting
Phase 3

A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

Diabetes Mellitus, Type 1Impaired Hypoglycemic AwarenessSevere Hypoglycemia
Vertex Pharmaceuticals Incorporated52 enrolled29 locationsNCT04786262
Recruiting

Cortisol and Obesity - A Vicious Cycle? Hypoglycemia After Bariatric Surgery - Association With Cortisol Metabolism?

Postbariatric Hypoglycemia
Esbjerg Hospital - University Hospital of Southern Denmark100 enrolled1 locationNCT06896682
Recruiting
Phase 1Phase 2

A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

Metabolic DiseaseDiabetes Mellitus, Type 1Type 1 Diabetes+14 more
Otsuka Pharmaceutical Factory, Inc.13 enrolled1 locationNCT06575426
Recruiting
Early Phase 1

Effect of C-peptide on Hypoglycemic Counterregulation

Type 1 DiabetesHypoglycemia
University of Cincinnati38 enrolled1 locationNCT06470295
Recruiting
Not Applicable

Monitoring Exhaled Breath to Noninvasively Detect Glycemic Events

DiabetesHyperglycemiaHypoglycemia
Indiana University30 enrolled1 locationNCT06893341
Recruiting
Phase 4

Pasteurised Donor Human Milk Supplementation for Term Babies

Metabolic ComplicationNeonatal Hypoglycemia
The University of Queensland1,444 enrolled4 locationsNCT06993103
Recruiting
Phase 2

Study to Evaluate Efficacy and Dose Response of Imapextide (STEADI)

Postbariatric Hypoglycemia
MBX Biosciences10 enrolled4 locationsNCT07029412
Recruiting
Not Applicable

Intrapartum Glucose Control and Risk of Neonatal Hypoglycemia

Gestational Diabetes Mellitus in PregnancyNeonatal HypoglycemiaPregestational Diabetes Mellitus
University of Pittsburgh218 enrolled1 locationNCT06643351
Recruiting

"Sexual Activity and Hypoglycemia Risk in Adults With Type 1 or Type 2 Diabetes Using Insulin Therapy and Continuous Glucose Monitoring"

Type 2 Diabetes (T2DM)HypoglycemiaType 1 Diabetes (T1D)
Medical University of Warsaw100 enrolled1 locationNCT07286500
Recruiting

Precision Subclassification of Mental Health in Diabetes: Digital Twins for Precision Mental Health to Track Subgroups

Depression - Major Depressive DisorderAnorexia NervosaBulimia Nervosa+17 more
Forschungsinstitut der Diabetes Akademie Mergentheim1,809 enrolled3 locationsNCT07212075
Recruiting

External Carotid Blood Flow in Individuals With Post-Bariatric Hypoglycemia

HypoglycemiaCerebral Blood Flow
Joslin Diabetes Center5 enrolled1 locationNCT07082478
Recruiting

Fasting Induced Hypoglycaemia in Anaesthetised Paediatric Patients

AnesthesiaPediatricsHypoglycemia; Iatrogenic
Guy's and St Thomas' NHS Foundation Trust6,580 enrolled3 locationsNCT07259629
Recruiting
Phase 2

Oral Glibenclamide in Preterm Infants With Hyperglycaemia (GALOP)

PretermTransient; Hypoglycemia, NeonatalGlibenclamide Adverse Reaction
Assistance Publique - Hôpitaux de Paris35 enrolled1 locationNCT05687500
Recruiting
Early Phase 1

Differing Levels of Hypoglycemia

Hypoglycemia
University of Maryland, Baltimore32 enrolled2 locationsNCT02445781
Recruiting
Not Applicable

The Feasibility of Cream for Treatment of Neonatal Hypoglycemia

Neonatal Hypoglycemia
Baylor Research Institute75 enrolled1 locationNCT07217483
Recruiting
Not Applicable

Endoscopic Ultrasound-guided Large Diameter Lumen-apposing Metal Stent Gastro-gastrostomy for Bypass Reversal in Patients With Roux-en-y Gastric Bypass

Gastric Outlet ObstructionHypoglycemiaSteatohepatitis+2 more
University Hospital, Ghent20 enrolled2 locationsNCT05640947