Hypoglycemia Clinical Trials

48 recruitingLast updated: June 18, 2026

There are 48 actively recruiting hypoglycemia clinical trials across 19 countries. Studies span Not Applicable, Phase 2, Early Phase 1, Phase 1, Phase 3, Phase 4. Top locations include San Antonio, Texas, United States, Pittsburgh, Pennsylvania, United States, Baltimore, Maryland, United States. Updated daily from ClinicalTrials.gov.


Hypoglycemia Trials at a Glance

48 actively recruiting trials for hypoglycemia are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Not Applicable with 20 trials, with the heaviest enrollment activity in San Antonio, Pittsburgh, and Baltimore. Lead sponsors running hypoglycemia studies include Indiana University, Milton S. Hershey Medical Center, and The University of Texas Health Science Center at San Antonio.

Browse hypoglycemia trials by phase

Treatments under study

About Hypoglycemia Clinical Trials

Looking for clinical trials for Hypoglycemia? There are currently 22 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Hypoglycemia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Hypoglycemia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 48 trials

Recruiting
Not Applicable

Impact of MEnstruation on Glycemic Response and Exercise In Females With Type 1 Diabetes

Type 1 DiabetesHypoglycemiaHyperglycaemia Due to Type 1 Diabetes Mellitus+1 more
University of Colorado, Denver150 enrolled1 locationNCT06297980
Recruiting
Early Phase 1

Regulation of Brain Glucose Metabolism in Type 1 Diabetes

Diabetes Mellitus, Type 1Hypoglycemia Unawareness
Yale University16 enrolled1 locationNCT05317455
Recruiting

Diagnosing and Treating Low Blood Sugar Levels

InsulinomaHypoglycemia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1,500 enrolled1 locationNCT00001276
Recruiting
Not Applicable

Diabetes Clinical Decision Support

DiabetesPrediabetesHyperglycemia+2 more
Milton S. Hershey Medical Center15,732 enrolled2 locationsNCT05447806
Recruiting
Not Applicable

Monitoring Exhaled Breath to Noninvasively Detect Glycemic Events

DiabetesHyperglycemiaHypoglycemia
Indiana University30 enrolled1 locationNCT06893341
Recruiting
Not Applicable

Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes

DementiaDiabetesHypoglycemia+1 more
Indiana University62 enrolled1 locationNCT05643144
Recruiting

A Study of Glycemic Control in Left Ventricular Assist

HyperglycemiaHypoglycemiaType 2 Diabetes Mellitus
Mayo Clinic20 enrolled1 locationNCT05933161
Recruiting
Phase 2

A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes

Type 1 Diabetes Mellitus With Hypoglycemia
Zucara Therapeutics Inc.186 enrolled46 locationsNCT05762107
Recruiting
Phase 2

Restoration of Hypoglycemia Awareness With Metoclopramide

Hypoglycemia Unawareness
Simon Fisher36 enrolled2 locationsNCT03970720
Recruiting
Phase 3

A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

Diabetes Mellitus, Type 1Impaired Hypoglycemic AwarenessSevere Hypoglycemia
Vertex Pharmaceuticals Incorporated52 enrolled29 locationsNCT04786262
Recruiting

Cortisol and Obesity - A Vicious Cycle? Hypoglycemia After Bariatric Surgery - Association With Cortisol Metabolism?

Postbariatric Hypoglycemia
Esbjerg Hospital - University Hospital of Southern Denmark100 enrolled1 locationNCT06896682
Recruiting
Phase 1Phase 2

A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

Metabolic DiseaseDiabetes Mellitus, Type 1Type 1 Diabetes+14 more
Otsuka Pharmaceutical Factory, Inc.13 enrolled1 locationNCT06575426
Recruiting
Not Applicable

Continuous Glucose Monitoring With iCan i3 in Post-Bariatric Patients With Late Dumping Syndrome

Post-Bariatric HypoglycemiaDumping syndrome
Kaiser Clinic and Hospital60 enrolled1 locationNCT07440706
Recruiting
Early Phase 1

Effect of C-peptide on Hypoglycemic Counterregulation

Type 1 DiabetesHypoglycemia
University of Cincinnati38 enrolled1 locationNCT06470295
Recruiting
Phase 4

Pasteurised Donor Human Milk Supplementation for Term Babies

neonatal intensive care unitMental Health IssueHospital Length of Stay+4 more
The University of Queensland1,444 enrolled4 locationsNCT06993103
Recruiting
Phase 2

Study to Evaluate Efficacy and Dose Response of Imapextide (STEADI)

Postbariatric Hypoglycemia
MBX Biosciences10 enrolled4 locationsNCT07029412
Recruiting
Not Applicable

Intrapartum Glucose Control and Risk of Neonatal Hypoglycemia

Gestational Diabetes Mellitus in PregnancyNeonatal HypoglycemiaPregestational Diabetes Mellitus
University of Pittsburgh218 enrolled1 locationNCT06643351
Recruiting

"Sexual Activity and Hypoglycemia Risk in Adults With Type 1 or Type 2 Diabetes Using Insulin Therapy and Continuous Glucose Monitoring"

Type 2 Diabetes (T2DM)HypoglycemiaType 1 Diabetes (T1D)
Medical University of Warsaw100 enrolled1 locationNCT07286500
Recruiting

Precision Subclassification of Mental Health in Diabetes: Digital Twins for Precision Mental Health to Track Subgroups

Depression - Major Depressive DisorderAnorexia NervosaBulimia Nervosa+17 more
Forschungsinstitut der Diabetes Akademie Mergentheim1,809 enrolled3 locationsNCT07212075
Recruiting

External Carotid Blood Flow in Individuals With Post-Bariatric Hypoglycemia

HypoglycemiaCerebral Blood Flow
Joslin Diabetes Center5 enrolled1 locationNCT07082478