Phase 3 Inflammation Clinical Trials

19 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 119 of 19 trials

Recruiting
Phase 3

A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation

Heart FailureSystemic Inflammation
Novo Nordisk A/S680 enrolled240 locationsNCT06200207
Recruiting
Phase 3

Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk

Peripheral Arterial DiseaseInflammationAtherosclerosis of Extremities
Population Health Research Institute6,150 enrolled70 locationsNCT04774159
Recruiting
Phase 2Phase 3

Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women

DepressionAnxietyInflammation+9 more
Cedars-Sinai Medical Center150 enrolled1 locationNCT05552053
Recruiting
Phase 3

Study on Ketorolac for Improving Outcomes and Prognosis in Patients With Stanford Type A Aortic Dissection

InflammationAortic Dissection
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School360 enrolled1 locationNCT06968806
Recruiting
Phase 2Phase 3

Using a Contact Dermatitis Model With Biologic Medications to Study Skin Inflammation

Skin InflammationAllergic Contact Dermatitis
Wei-Che Ko45 enrolled1 locationNCT05535738
Recruiting
Phase 3

Treating Immuno-metabolic Depression With Anti-inflammatory Drugs

InflammationDepressive Disorder, Major
Amsterdam UMC, location VUmc140 enrolled1 locationNCT05415397
Recruiting
Phase 3

Specifying the Anti-inflammatory Effects of Ziltivekimab

AtherosclerosisInflammation
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)40 enrolled1 locationNCT06263244
Recruiting
Phase 3

A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE

Macular Edema Secondary to Inflammation
Kodiak Sciences Inc150 enrolled33 locationsNCT06996080
Recruiting
Phase 3

A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK

Macular Edema Secondary to Inflammation
Kodiak Sciences Inc150 enrolled33 locationsNCT06990399
Recruiting
Phase 3

Comparison of Topical Treatment for Inflammatory Secretions of the Conjonctiva (Patients With Ocular Prostheses)

Ocular InflammationOcular Prostheses
Agnes30 enrolled1 locationNCT05668455
Recruiting
Phase 3

Azathioprine in MOGAD

Central Nervous System InflammationMOG-IgG Associated Disease
Hospices Civils de Lyon126 enrolled17 locationsNCT05349006
Recruiting
Phase 2Phase 3

Effect of Colchicine on the Progression of Aortic Valve Stenosis - a Pilot Study

InflammationAortic Stenosis
Ottawa Heart Institute Research Corporation24 enrolled1 locationNCT05253794
Recruiting
Phase 3

INflammation-based Stratification for Immune-Targeted Augmentation in Major Depressive Disorder

InflammationMajor Depressive Disorder
Universiteit Antwerpen240 enrolled3 locationsNCT05644301
Recruiting
Phase 3

Canadian Study of Arterial Inflammation in Patients With Diabetes and Vascular Events: EvaluatioN of Colchicine

Cardiovascular DiseasesDiabetesAtherosclerosis+1 more
Ottawa Heart Institute Research Corporation115 enrolled2 locationsNCT04181996
Recruiting
Phase 2Phase 3

Preventing Systemic Inflammation After Cardiac Surgery With Alkaline Phosphatase

Systemic Inflammation
Alloksys Life Sciences B.V.1,250 enrolled21 locationsNCT03050476
Not Yet Recruiting
Phase 2Phase 3

Randomised controlled trial to determine the effects of short-term oral cannabidiol (CBD) ingestion on inflammation, muscle damage and functional recovery following downhill running in healthy untrained individuals.

Inflammation
Cannvalate40 enrolled1 locationACTRN12619001120167
Completed
Phase 3

The impact of continuous terlipressin infusion on complications of end-stage liver disease

CirrhosisAscitesMalnutrition+2 more
Austin Health30 enrolled1 locationACTRN12619000891123
Active
Phase 3Phase 4

Investigation of the Effects of Longvida Curcumin on Cognitive Function, Mood and Biomarkers of Health.

Brain function (fMRI)Psychological wellbeing (mood, stress fatigue, sleep)Inflammation+2 more
Swinburne University of Technology, Centre for Human Psychopharmacology80 enrolled1 locationACTRN12616000484448
Not Yet Recruiting
Phase 3

Interappointment pain experience with a new endodontic medicament: a randomised controlled trial

Apical periodontitisPulpal inflammation
The University of Melbourne24 enrolled1 locationACTRN12612000630819