Phase 3 Inflammation Clinical Trials
23 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 23 trials
Recruiting
Phase 3
PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation
InfectionsInjury LegAmputation+6 more
Major Extremity Trauma Research Consortium250 enrolled13 locationsNCT05699174
Recruiting
Phase 3
Hydrocortisone Plus Fludrocortisone in High-risk Patients Undergoing for Cardiac Surgery
Inflammation in Cardiac Surgery
Centre Hospitalier Universitaire, Amiens196 enrolled1 locationNCT07037043
Recruiting
Phase 3
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE
Macular Edema Secondary to Inflammation
Kodiak Sciences Inc300 enrolled56 locationsNCT06996080
Recruiting
Phase 3
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK
Macular Edema Secondary to Inflammation
Kodiak Sciences Inc600 enrolled56 locationsNCT06990399
Recruiting
Phase 3
Targeting Vascular INflammation in Patients With Community-Acquired Pneumonia
InflammationCommunity-Acquired Pneumonia (CAP)Inflammation Plaque, Atherosclerotic
Ottawa Heart Institute Research Corporation168 enrolled1 locationNCT06710080
Recruiting
Phase 2Phase 3
The Investigators Will Evaluate the Diagnostic Performance of [18F]-AlF-FAPI-74 PET/CT in Inflammatory Disorders and Compare it With the Current Gold Standard for Inflammation, FDG PET/CT, in Three Patient Cohort: Patients Presenting With Fever of Unknown Origin, IgG4-RD and AxSpA.
Axial Spondylarthritis (axSpA)IgG4-related DiseaseInflammation of Unknown Origin+1 more
Universitaire Ziekenhuizen KU Leuven140 enrolled1 locationNCT07535554
Recruiting
Phase 3
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation
Heart FailureSystemic Inflammation
Novo Nordisk A/S680 enrolled240 locationsNCT06200207
Recruiting
Phase 3
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk
Peripheral Arterial DiseaseInflammationAtherosclerosis of Extremities
Population Health Research Institute6,150 enrolled70 locationsNCT04774159
Recruiting
Phase 2Phase 3
Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women
DepressionAnxietyInflammation+9 more
Cedars-Sinai Medical Center150 enrolled1 locationNCT05552053
Recruiting
Phase 3
Study on Ketorolac for Improving Outcomes and Prognosis in Patients With Stanford Type A Aortic Dissection
InflammationAortic Dissection
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School360 enrolled1 locationNCT06968806
Recruiting
Phase 2Phase 3
Using a Contact Dermatitis Model With Biologic Medications to Study Skin Inflammation
Skin InflammationAllergic Contact Dermatitis
Wei-Che Ko45 enrolled1 locationNCT05535738
Recruiting
Phase 3
Treating Immuno-metabolic Depression With Anti-inflammatory Drugs
InflammationDepressive Disorder, Major
Amsterdam UMC, location VUmc140 enrolled1 locationNCT05415397
Recruiting
Phase 3
Specifying the Anti-inflammatory Effects of Ziltivekimab
AtherosclerosisInflammation
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)40 enrolled1 locationNCT06263244
Recruiting
Phase 3
Comparison of Topical Treatment for Inflammatory Secretions of the Conjonctiva (Patients With Ocular Prostheses)
Ocular InflammationOcular Prostheses
Agnes30 enrolled1 locationNCT05668455
Recruiting
Phase 3
Azathioprine in MOGAD
Central Nervous System InflammationMOG-IgG Associated Disease
Hospices Civils de Lyon126 enrolled17 locationsNCT05349006
Recruiting
Phase 2Phase 3
Effect of Colchicine on the Progression of Aortic Valve Stenosis - a Pilot Study
InflammationAortic Stenosis
Ottawa Heart Institute Research Corporation24 enrolled1 locationNCT05253794
Recruiting
Phase 3
INflammation-based Stratification for Immune-Targeted Augmentation in Major Depressive Disorder
InflammationMajor Depressive Disorder
Universiteit Antwerpen240 enrolled3 locationsNCT05644301
Recruiting
Phase 3
Canadian Study of Arterial Inflammation in Patients With Diabetes and Vascular Events: EvaluatioN of Colchicine
Cardiovascular DiseasesDiabetesAtherosclerosis+1 more
Ottawa Heart Institute Research Corporation115 enrolled2 locationsNCT04181996
Recruiting
Phase 2Phase 3
Preventing Systemic Inflammation After Cardiac Surgery With Alkaline Phosphatase
Systemic Inflammation
Alloksys Life Sciences B.V.1,250 enrolled21 locationsNCT03050476
Not Yet Recruiting
Phase 2Phase 3
Randomised controlled trial to determine the effects of short-term oral cannabidiol (CBD) ingestion on inflammation, muscle damage and functional recovery following downhill running in healthy untrained individuals.
Inflammation
Cannvalate40 enrolled1 locationACTRN12619001120167