Phase 2 Inflammation Clinical Trials

37 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 37 trials

Recruiting
Phase 2

A Study to Learn About the Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Late Isolated Microvascular Inflammation

Microvascular Inflammation
Biogen81 enrolled23 locationsNCT07219043
Recruiting
Phase 2

Effects of IL-1 Beta Inhibition on Vascular Inflammation in TET2 Clonal Hematopoiesis

ASCVDVascular InflammationASCVD Management
Massachusetts General Hospital120 enrolled1 locationNCT06691217
Recruiting
Phase 2

Topical Ketotifen 0.25% for Secondary Vestibulodynia

VulvodyniaProvoked VestibulodyniaSecondary Provoked Vestibulodynia+4 more
Center for Vulvovaginal Disorders54 enrolled3 locationsNCT07257029
Recruiting
Phase 2

Reducing Frailty for Older Cancer Survivors Using Supplements II

FrailtyInflammation
University of Rochester118 enrolled1 locationNCT06068543
Recruiting
Phase 2

Efficacy of LoDoCo in Improving Exercise Capacity Among Patients With HFpEF and Inflammation

Heart FailureInflammation
University of Texas Southwestern Medical Center60 enrolled1 locationNCT06130059
Recruiting
Phase 2

Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy

Recurrent Grade 3b Follicular LymphomaRefractory Grade 3b Follicular LymphomaRecurrent Transformed Non-Hodgkin Lymphoma+28 more
Mayo Clinic41 enrolled7 locationsNCT06834373
Recruiting
Phase 2

Focused Orticumab Research for Treating Inflammation in Coronary Arteries

Heart DiseaseInflammationCoronary Arterial Disease (CAD)+3 more
Abcentra240 enrolled41 locationsNCT06927739
Recruiting
Phase 1Phase 2

Single and Multiple Ascending Oral Doses of Avenanthramide

Inflammation
Montreal Heart Institute96 enrolled1 locationNCT06101784
Recruiting
Phase 2

The Effect of Colchicine, on Insulin Sensitivity in Individuals With Type 1 Diabetes and Systemic Low-grade Inflammation

Type 1 DiabetesInsulin SensitivityChronic Inflammation
Asger Lund, MD26 enrolled1 locationNCT07247734
Recruiting
Phase 2Phase 3

Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women

DepressionAnxietyInflammation+9 more
Cedars-Sinai Medical Center150 enrolled1 locationNCT05552053
Recruiting
Phase 2

Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV

Obesity and OverweightHIVChronic Inflammation
University of Hawaii12 enrolled1 locationNCT06935838
Recruiting
Phase 2

Clinical Trial of the Seaweed Supplement Fucoidan in Survivors of Cancer

FatigueInflammation
University of Rochester40 enrolled1 locationNCT06295588
Recruiting
Phase 2Phase 3

Using a Contact Dermatitis Model With Biologic Medications to Study Skin Inflammation

Skin InflammationAllergic Contact Dermatitis
Wei-Che Ko45 enrolled1 locationNCT05535738
Recruiting
Phase 2

Treatment of ARDS With Instilled T3

Lung InflammationARDS, HumanPulmonary Edema+2 more
University of Minnesota68 enrolled2 locationsNCT04115514
Not Yet Recruiting
Phase 2

Efficacy of assigning treatment for participants with VEXAS syndrome with lenzilumab plus azacitidine

V - vacuoles are often seen in cells identified in bone marrow biopsies from patients with VEXAS syndrome. E - E1 ubiquitin activating enzyme, encoded by the UBA1 gene which is mutated in patients X - the UBA1 gene is located on the X chromosome. A - patients have autoinflammation. S - the mutations are somatic, meaning they are acquired at some point in life and not inherited. (VEXAS)
South Australian Health & Medical Research Institute Ltd10 enrolled1 locationACTRN12625000619448
Recruiting
Phase 1Phase 2

Roxadustat's Effect on Heart, Nutrition, and Inflammation in Hemodialysis Patients

Cardiovascular Diseases (CVD)Kidney Failure, ChronicMalnutrition-Inflammation Syndrome+1 more
Mansoura University46 enrolled1 locationNCT06903559
Recruiting
Phase 2

Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab

InflammationDepressive Disorder, Major
Massachusetts General Hospital100 enrolled1 locationNCT06136546
Recruiting
Phase 2

Passive Stretching in Peripheral Arterial Disease Patients

Peripheral Arterial DiseaseInflammationWalking, Difficulty
University of Wisconsin, La Crosse64 enrolled1 locationNCT06420752
Recruiting
Phase 2Phase 3

Effect of Colchicine on the Progression of Aortic Valve Stenosis - a Pilot Study

InflammationAortic Stenosis
Ottawa Heart Institute Research Corporation24 enrolled1 locationNCT05253794
Recruiting
Phase 2

Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock

SepsisPathologic ProcessesInfections+4 more
Ottawa Hospital Research Institute296 enrolled2 locationsNCT05969275