Phase 1 Inflammation Clinical Trials
15 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–15 of 15 trials
Recruiting
Phase 1
Novel Approaches for Improving Vascular Function in Veterans With HFpEF
InflammationHeart Failure With Preserved Ejection Fraction
VA Office of Research and Development90 enrolled1 locationNCT06312748
Recruiting
Phase 1Phase 2
Single and Multiple Ascending Oral Doses of Avenanthramide
Inflammation
Montreal Heart Institute96 enrolled1 locationNCT06101784
Recruiting
Phase 1
Safety, Tolerability, and Distribution of Laquinimod Eye Drops : The LION Study
InflammationUveitis
Quan Dong Nguyen12 enrolled1 locationNCT06161415
Recruiting
Phase 1Phase 2
Roxadustat's Effect on Heart, Nutrition, and Inflammation in Hemodialysis Patients
Cardiovascular Diseases (CVD)Kidney Failure, ChronicMalnutrition-Inflammation Syndrome+1 more
Mansoura University46 enrolled1 locationNCT06903559
Recruiting
Phase 1Phase 2
Multimodal Imaging Assessment of the Inflammatory Atheromatous Plaque
InflammationCarotid Artery DiseasesAtheromatous Plaques
University of Lausanne Hospitals20 enrolled1 locationNCT01608516
Completed
Phase 1
A Phase I Clinical Trial of IHL-675A to Assess Safety and Pharmacokinetics in Healthy Volunteers
Inflammation
Incannex Healthcare Ltd36 enrolled1 locationACTRN12622000289718
Completed
Phase 1
A First-In-Human study to evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Ascending Doses of NT-0249 in Healthy Volunteers.
Inflammation and Immune SystemInflammation
NodThera72 enrolled1 locationACTRN12622000195752
Completed
Phase 1
A First-In-Human study to evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Ascending Doses of NT-0796 in Healthy Volunteers.
Inflammation
NodThera88 enrolled1 locationACTRN12621001082897
Completed
Phase 1
The New Zealand Indigo naturalis dose-escalation study (NZ-INDES): a study to investigate its effect on immune responses in healthy volunteers
Inflammation
Malaghan Institute of Medical Research25 enrolled1 locationACTRN12621000097842
Terminated
Phase 1
A First-In-Human study to evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Ascending Doses of NT-0167 in Healthy Volunteers.
Inflammation
NodThera80 enrolled1 locationACTRN12620000685910
Completed
Phase 1
A Phase 1 study to evaluate Safety, Tolerability and Pharmacokinetics of Ultramicronized-Palmitoylethanolamide (PEA) in Healthy Subjects.
Chronic PainInflammation
FSD Pharma Inc.48 enrolled1 locationACTRN12620000213943
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of paracetamol / ibuprofen / doxylamine tablet against the innovator paracetamol / codeine phosphate hemihydrate / doxylamine succinate tablets and paracetamol / ibuprofen tablet conducted under fasting conditions in healthy male and female volunteers
PainInflammationAllergy+1 more
Zenith Technology Corporation Limited24 enrolled1 locationACTRN12619001017112
Completed
Phase 1
A Phase I study of inhaled PB01 in healthy male volunteers to assess the anti-inflammatory effects of PB01 on lung inflammation.
Airway inflammation and fibrosis
Paranta Biosciences Ltd24 enrolled1 locationACTRN12616000496415
Completed
Phase 1
A Phase I study of orally inhaled PB01 in healthy male participants following single and repeat administration.
Airway inflammation and fibrosis
Paranta Biosciences Ltd56 enrolled1 locationACTRN12615000984594
Completed
Phase 1
Study of the uptake into, and removal from the human body, of meloxicam when taken in two different forms of the medication: a new formulation of meloxicam, Meloxicam Nanoformulation capsules; and marketed capsules (known as Mobic (Registered trademark(R)), when taken after a fast and after a high fat breakfast.
Inflammation
iCeutica Pty Ltd14 enrolled1 locationACTRN12609000474257