Invasive mechanical ventilation Clinical Trials

15 recruitingLast updated: May 11, 2026

There are 15 actively recruiting invasive mechanical ventilation clinical trials across 16 countries. Studies span Not Applicable, Phase 2, Phase 3. Top locations include Paris, France, Belgrade, Serbia, Bern, Switzerland. Updated daily from ClinicalTrials.gov.


Invasive mechanical ventilation Trials at a Glance

15 actively recruiting trials for invasive mechanical ventilation are listed on ClinicalTrialsFinder across 6 cities in 16 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Paris, Belgrade, and Bern. Lead sponsors running invasive mechanical ventilation studies include Assistance Publique - Hôpitaux de Paris, Centre Hospitalier Régional d'Orléans, and Ankara University.

Browse invasive mechanical ventilation trials by phase

Treatments under study

About Invasive mechanical ventilation Clinical Trials

Looking for clinical trials for Invasive mechanical ventilation? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Invasive mechanical ventilation trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Invasive mechanical ventilation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 115 of 15 trials

Recruiting

A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score

extubation failureRespiratory FailureWeaning Invasive Mechanical Ventilation+5 more
Medipol University470 enrolled7 locationsNCT07098611
Recruiting

Evaluation and Further Development of an Artificial Intelligence-based Algorithm for Clinical Decision Support

Invasive mechanical ventilation
Technische Universität Dresden318,542 enrolled8 locationsNCT05668637
Recruiting

Multidimensional Correlation Analysis of Heart Rate Variability and Weaning Assessment Parameters in Critically Mechanically Ventilated Patients

Weaning Invasive Mechanical Ventilation
Fu Jen Catholic University Hospital100 enrolled1 locationNCT07455214
Recruiting
Phase 3

Efficacy of Dexmedetomidine Versus Midazolam Sedation on Extubation Time in Mechanically Ventilated Preterm Infants

Preterm neonateSedation for Invasive Mechanical VentilationVery Preterm Neonates With Sedation for Invasive Mechanical Ventilation
Assistance Publique - Hôpitaux de Paris380 enrolled1 locationNCT06878703
Recruiting
Not Applicable

Lung Recruitment During Chest Physiotherapy in Mechanically Ventilated Patients

Invasive mechanical ventilationAirway ClearanceIntensive Care+1 more
Assistance Publique - Hôpitaux de Paris40 enrolled1 locationNCT06805357
Recruiting
Not Applicable

Endotracheal Suctionning During Positive Pressure Extubation in ICU

Weaning Invasive Mechanical VentilationExtubationOxygen Saturation Measurement+2 more
Centre Hospitalier Régional d'Orléans120 enrolled1 locationNCT07130123
Recruiting

Evaluation of Rehabilitation Practices in the Intensive Care Unit

Invasive mechanical ventilationRehabilitation Exercise of ICU Patients
French Society for Intensive Care1,000 enrolled1 locationNCT06969443
Recruiting
Not Applicable

Ultrasound Evaluation of Cardiac Function During Spontaneous Breathing Trials

Weaning Invasive Mechanical VentilationWeaning-induced Pulmonary EdemaWeaning Failure of Mechanical Ventilation+2 more
Centre Hospitalier Régional d'Orléans24 enrolled1 locationNCT06923267
Recruiting
Not Applicable

Preoxygenation for Tracheal Aspirations in Intensive Care

ICU Patients Under Invasive Mechanical Ventilation
Assistance Publique - Hôpitaux de Paris2,260 enrolled1 locationNCT06421012
Recruiting

Dyspnea Facial Recognition During Weaning

Dyspnea Invasive Mechanical Ventilation-associated
Assistance Publique - Hôpitaux de Paris100 enrolled1 locationNCT05163275
Recruiting

The Effect of NOn-invasive Respiratory Support on outcoMe and Its Risks in SARS-COV-2-related Hypoxemic Respiratory Failure

Target Trial Emulation, Invasive Mechanical Ventilation
Erasmus Medical Center50,000 enrolled1 locationNCT06757166
Recruiting

Assessment of Ventilation Parameters for Extubation Prediction in ICU

Invasive mechanical ventilationAcute Respiratory Failure
Ankara University100 enrolled1 locationNCT06531005
Recruiting
Not Applicable

The External Diaphragm Pacemaker Assisted Extubation in Premature Infants With Invasive Mechanical Ventilation

Invasive mechanical ventilationExtubation
Children's Hospital of Chongqing Medical University40 enrolled1 locationNCT06404294
Recruiting

Clinical Empirical Research of ARDS

Invasive Mechanical Ventilation ARDS
Chinese PLA General Hospital200 enrolled1 locationNCT05922826
Recruiting
Phase 2

Feasibility and safety of conservative versus liberal oxygen targets in the mechanically ventilated patients.

Critically ill patients requiring invasive mechanical ventilation
John Hunter100 enrolled4 locationsACTRN12613000505707