Major Depressive Disorder Clinical Trials in Toronto, Ontario
26 recruitingToronto, Ontario, Canada
Showing 1–20 of 26 trials
Recruiting
Phase 3
Study to Assess the Safety and Effectiveness of NMRA-335140-501
Major Depressive Disorder
Neumora Therapeutics, Inc.1,000 enrolled178 locationsNCT06029439
Recruiting
Phase 2
A Randomized Neuroimaging Trial of Psilocybin in Depression
Depressive DisorderMajor Depressive Disorder
Sunnybrook Health Sciences Centre50 enrolled1 locationNCT06072898
Recruiting
Not Applicable
rTMS for Depression in Young Adults With Autism
Autism Spectrum DisorderMajor Depressive Disorder
Centre for Addiction and Mental Health80 enrolled1 locationNCT04972136
Recruiting
Validating the On-line Creyos Cognitive Assessment Platform in Older Adults With Major Depressive Disorder or Mild Cognitive Impairment
Mild Cognitive Impairment (MCI)Major Depressive Disorder, RemittedHealthy Controls Group - Age and Sex-matched
Centre for Addiction and Mental Health150 enrolled3 locationsNCT06780917
Recruiting
Phase 4
Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)
Major Depressive Disorder
Nova Scotia Health Authority400 enrolled7 locationsNCT05017311
Recruiting
Not Applicable
Accelerated vs. Conventional Theta Burst Stimulation for Late-life Depression
Depression - Major Depressive DisorderMood DisordersLate Life Depression (LLD)+1 more
Centre for Addiction and Mental Health280 enrolled2 locationsNCT06854367
Recruiting
Not Applicable
Integrated Suicide & Trauma Therapy for Suicide Risk
SuicideMajor Depressive DisorderTrauma
Unity Health Toronto20 enrolled1 locationNCT05613972
Recruiting
Phase 2
i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial
SuicideMajor Depressive DisorderTreatment Resistant Depression
University Health Network, Toronto110 enrolled1 locationNCT06480500
Recruiting
Not Applicable
Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults
Alzheimer DiseaseMajor Depressive DisorderMild Cognitive Impairment
Rotman Research Institute at Baycrest28 enrolled1 locationNCT03665831
Recruiting
Phase 1
Theta-Burst Stimulation to Treat Depression
Major Depressive Disorder (MDD)
Centre for Addiction and Mental Health84 enrolled1 locationNCT07033780
Recruiting
Not Applicable
Temporal Interference and Depression
Major Depressive Disorder
Unity Health Toronto30 enrolled1 locationNCT05295888
Recruiting
Not Applicable
Mood And Kids diEt (MAKE-It) Pilot Trial
Depression - Major Depressive DisorderAdolescent
The Hospital for Sick Children20 enrolled1 locationNCT06716034
Recruiting
Not Applicable
Extended Effects of Cannabis Abstinence on Clinical Symptoms and Cognition in Depression
Cognitive ImpairmentCannabis UseMajor Depressive Disorder
Centre for Addiction and Mental Health52 enrolled1 locationNCT04935619
Recruiting
Not Applicable
The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant Depression
Major Depressive DisorderTreatment Resistant Depression
Unity Health Toronto50 enrolled1 locationNCT06163625
Recruiting
Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot Study
Major Depressive Disorder (MDD)Major Depressive EpisodeTreatment-Resistant Major Depressive Disorder
Unity Health Toronto200 enrolled1 locationNCT06732089
Recruiting
Not Applicable
Interleaved TMS-fMRI in Ultra-treatment Resistant Depression
Major Depressive Disorder
Sunnybrook Health Sciences Centre88 enrolled1 locationNCT05813093
Recruiting
Effect of Suicidality on Social Cognition
SuicideMajor Depressive Disorder
Unity Health Toronto150 enrolled1 locationNCT06163612
Recruiting
Phase 2
Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of Psilocybin
DepressionMajor Depressive Disorder
University Health Network, Toronto92 enrolled1 locationNCT06341426
Recruiting
Not Applicable
Cognitive Dysfunction in the Addictions Study - Project 4 (P4)
Major Depressive DisorderAlcohol Use Disorder
Centre for Addiction and Mental Health40 enrolled1 locationNCT06299787
Recruiting
Not Applicable
E-field Guided iTBS for Treatment Resistant Depression
Major Depressive Disorder
Centre for Addiction and Mental Health110 enrolled2 locationsNCT05583747