Phase 4 Malaria Clinical Trials
98 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 98 trials
Completed
Phase 4
Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum and vivax malaria in Eritrea in 2024
Malaria
Ministry of Health480 enrolled1 locationACTRN12626000256370
Recruiting
Phase 4
OPTImizing Malaria And HIV Treatment in a Shifting Landscape in Africa
Malaria
Yale University380 enrolled2 locationsNCT06967519
Recruiting
Phase 4
Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics
PregnancyMalaria,FalciparumMalaria in Pregnancy+1 more
Duke University2,500 enrolled2 locationsNCT05757167
Completed
Phase 4
Efficacy and safety of artesunate-amodiaquine for the treatment of uncomplicated Plasmodium falciparum in Eritrea in 2022
Malaria
Ministry of Health352 enrolled1 locationACTRN12625001329459
Recruiting
Phase 4
PDMC Implementation Trial in Kenya
Severe MalariaSevere Anemia
Liverpool School of Tropical Medicine600 enrolled1 locationNCT06624631
Recruiting
Phase 4
Integrating Malaria Vaccine With Seasonal Malaria Chemoprevention in West Africa
Malaria Vaccine
Epicentre40,000 enrolled2 locationsNCT06860178
Recruiting
Phase 4
Post-discharge Malaria Chemoprevention Implementation Trial in Benin
Severe MalariaSevere Anaemia
Institut de Recherche Clinique du Benin648 enrolled2 locationsNCT06601712
Recruiting
Phase 4
ACT vs CQ With Tafenoquine for P. Vivax Mono-infection
Plasmodium Vivax MalariaMalariaMalaria, Vivax
Shoklo Malaria Research Unit606 enrolled1 locationNCT05788094
Recruiting
Phase 4
The Transmission of Artemisinin Resistant Parasites Before and After Conventional Artemisinin-combination Therapy
Falciparum; Malaria
Infectious Diseases Research Collaboration, Uganda120 enrolled2 locationsNCT06347471
Recruiting
Phase 4
Southeast Asia Dose Optimization of Tafenoquine
Plasmodium Vivax Malaria
University of Oxford700 enrolled5 locationsNCT04704999
Not Yet Recruiting
Phase 4
Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria and chloroquine for Plasmodium vivax malaria in Nansang Township, Southern-Shan State, Myanmar
Plasmodium falciparum malaria
WHO Mekong Malaria Elimination Program160 enrolled1 locationACTRN12625000119493
Completed
Phase 4
Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Djibouti-ville, Djibout
Malaria
Ministry of Health of Djibouti88 enrolled1 locationACTRN12624000909527
Completed
Phase 4
Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Al Tor Bin Qais in Hajah, Yemen.
Malaria
The Ministry of Public Health and Population88 enrolled1 locationACTRN12624000526572
Completed
Phase 4
Efficacy and safety of artemether-lumafantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum in two sentinel sites in Togo
Malaria
Ministère de la Santé de l’Hygiène Publique et de l’accès Universel aux Soins352 enrolled1 locationACTRN12623000344695
Recruiting
Phase 4
Evaluation of the efficacy and safety of Artemether +Lumefantrine (Coartem®) with low-dose Primaquine for the treatment of uncomplicated Plasmodium falciparum and Plasmodium vivax malaria in three sites of Savanakhet, Salavanh, and Attopue province, Lao PDR (2022)
Malaria
Ministry of Health300 enrolled1 locationACTRN12623000241639
Not Yet Recruiting
Phase 4
Measurement of the level of performance of two malaria medicines (artemether-lumefantrine and dihydroartemisinin-piperaquine) for the treatment of uncomplicated malaria caused by malaria parasite called Plasmodium falciparum in Alikadam Upazila (sub-district) and Lama Upazila (subdistrict) of Bandarban district and Baghaichari Upazila (subdistrict) of Rangamati district, Bangladesh.
Febrile malaria patients aged more than 6 months with confirmed uncomplicated P. falciparum infection.
Ministry of Health and Family Welfare, Bangladesh360 enrolled1 locationACTRN12623000239662
Completed
Phase 4
Efficacy and safety of artesunate-amodiaquine and artemether-lumefantrine among children 6 to 59 months for the treatment of uncomplicated Plasmodium falciparum in Chad
Malaria
Ministry of Public Health180 enrolled1 locationACTRN12622001476729
Completed
Phase 4
Efficacy and safety of artemether- lumefantrine and artesunate - amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Mainland Tanzania
Malaria
National Institute for Medical Research176 enrolled1 locationACTRN12622001243707
Completed
Phase 4
Efficacy and safety Study of Artesunate+Sulphadoxine/Pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria and Chloroquine for Plasmodium vivax malaria in health facilities of Nangarhar and Laghman provinces of Afghanistan
Malaria
Ministry of Public Health Afghanistan240 enrolled1 locationACTRN12622000944730
Completed
Phase 4
Efficacy and safety of Artemether-Lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in different sentinel site in Sudan
Malaria
Ministry of Health264 enrolled1 locationACTRN12622000930785