Mental Illness Clinical Trials

13 recruiting

Mental Illness Trials at a Glance

27 actively recruiting trials for mental illness are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Not Applicable with 21 trials, with the heaviest enrollment activity in Alameda, Assen, and Ballarat. Lead sponsors running mental illness studies include VA Office of Research and Development, Boston University Charles River Campus, and Bjorn H. Ebdrup.

Browse mental illness trials by phase

Treatments under study

About Mental Illness Clinical Trials

Looking for clinical trials for Mental Illness? There are currently 13 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Mental Illness trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Mental Illness clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 27 trials

Recruiting
Not Applicable

ACT Group for Family Caregivers of Stroke Survivors

Caregiver BurdenCaregiver StressCaregiver Burnout+11 more
The Wright Institute30 enrolled1 locationNCT07528261
Recruiting
Not Applicable

Multimodal Physical Exercise Program (Physical Exercise for Psychosis) for People With Psychosis Treated With Long-Acting Injectable Antipsychotics

Psychotic DisordersSevere Mental IllnessSchizophrenia Spectrum Disorders (SSD)
University of Trás-os-Montes and Alto Douro44 enrolled1 locationNCT07360665
Recruiting
Not Applicable

Harm Reduction Services

Substance AbuseDrug UseMental Illness
NYU Langone Health200 enrolled3 locationsNCT05776316
Recruiting
Not Applicable

Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital

DepressionSerious Mental IllnessPsychotic Disorder+1 more
Massachusetts General Hospital40 enrolled1 locationNCT07359157
Recruiting

Validation of French PHQ-4 and PC-PTSD-5 Screening Scales

Mental Illness
Assistance Publique - Hôpitaux de Paris90 enrolled1 locationNCT07396623
Recruiting
Not Applicable

Enhancing Rehabilitation for Veterans With Serious Mental Illness

SchizophreniaPTSDBipolar Disorder+3 more
VA Office of Research and Development80 enrolled1 locationNCT06586164
Recruiting
Not Applicable

Group Intervention for Romantic Relationships in Young Adults With Severe Mental Illness

SchizophreniaMajor Depressive DisorderBipolar Disorder+1 more
Centre hospitalier de Ville-Evrard, France20 enrolled2 locationsNCT07316803
Recruiting
Not Applicable

Real-time Experiences, Physical Activity and Biological Outcomes in Personal Recovery Residents (EMPOWER-RES)

Severe Mental DisorderSevere Mental Illness
IRCCS Centro San Giovanni di Dio Fatebenefratelli72 enrolled3 locationsNCT06914622
Recruiting
Phase 2

Efficacy and Safety of HB-1 for Panic Disorder

Panic DisorderMental Illness
HB BioTech, LLC240 enrolled22 locationsNCT06483789
Recruiting
Not Applicable

Norwegian Mental Illness Heart Health Study

Severe Mental DisorderMetabolic Syndrome (MetS)Severe Mental Illness+5 more
Madeleine Elisabeth Angelsen70 enrolled1 locationNCT07085923
Recruiting
Not Applicable

Successful Transitions and Reintegration Tools for Veterans (START-VETS)

Substance Use DisorderMental IllnessRecently Incarcerated
VA Office of Research and Development20 enrolled1 locationNCT04366531
Recruiting
Not Applicable

The Barts Charity Children's Environmental Health Clinic

Health BehaviorEnvironmental ExposureAsthma in Children+1 more
Queen Mary University of London200 enrolled2 locationsNCT06447974
Recruiting
Not Applicable

Cognitive Remediation and Transcranial Direct Current Stimulation in Severe Mental Illness (SMI)

Severe Mental Illness
University of Groningen126 enrolled3 locationsNCT06378463
Recruiting
Not Applicable

Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use

SchizophreniaCannabis UseMajor Depressive Disorder+3 more
Nova Scotia Health Authority120 enrolled1 locationNCT03601026
Recruiting
Not Applicable

A Transdiagnostic Mentalization-based Intervention for Parents With Mental Disorders

Psychiatric DisorderSevere Mental DisorderMental Disorder+6 more
Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital170 enrolled2 locationsNCT06315114
Recruiting
Not Applicable

A Pilot Randomized Controlled Trial of the Hopeful and Healthy Living Program

Older AdultsSerious Mental Illness
Boston University Charles River Campus60 enrolled2 locationsNCT06940843
Recruiting
Not Applicable

Effectiveness of Mentalization-based Therapy (MBT)

Severe Mental Illness
Oulu University Hospital128 enrolled1 locationNCT06659211
Recruiting
Not Applicable

Comparative Effectiveness of IIMR Versus CDSMP

Chronic DiseaseMental Illness
Dartmouth-Hitchcock Medical Center600 enrolled2 locationsNCT03966872
Recruiting
Not Applicable

HEAlth Dialogues for Patients With Mental Illness in Primary Care

DeathDepressionStress+6 more
Region Skane400 enrolled1 locationNCT05181254
Recruiting
Not Applicable

Co-occurence of Mental Illness and Problematic Alcohol Use: an Internet-based Cognitive Behavior Therapy Intervention

Anxiety Disorder/Anxiety StateSleep ProblemsStress Disorders+6 more
Linkoeping University240 enrolled2 locationsNCT06789250