Myopathy Clinical Trials in London
24 recruitingLondon, United Kingdom
Showing 1–20 of 24 trials
Recruiting
Phase 3
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Novo Nordisk A/S1,280 enrolled292 locationsNCT07207811
Recruiting
Phase 3
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals1,750 enrolled240 locationsNCT07052903
Recruiting
A Study to Check Liver Health in Boys With XLMTM, a Serious Genetic Muscle Condition
X-linked Myotubular Myopathy
Astellas Gene Therapies50 enrolled10 locationsNCT06581146
Recruiting
Phase 2Phase 3
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
DermatomyositisIdiopathic Inflammatory MyopathyAnti-synthetase Syndrome+5 more
Cabaletta Bio74 enrolled35 locationsNCT06154252
Recruiting
Phase 2Phase 3
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Symptomatic Genetic Dilated Cardiomyopathy
Kardigan, Inc.332 enrolled56 locationsNCT07210723
Recruiting
Phase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
CardiomyopathiesAmyloidosisHeart Diseases+3 more
Eidos Therapeutics, a BridgeBio company587 enrolled103 locationsNCT06563895
Recruiting
Not Applicable
Physiological Versus Right Ventricular Outcome Trial Evaluated for Bradycardia Treatment Upgrades
Heart FailurePacing-Induced Cardiomyopathy
Imperial College London155 enrolled12 locationsNCT06052475
Recruiting
Phase 1Phase 2
ALXN2350 in Adult Participants With BAG3-Associated Dilated Cardiomyopathy
BAG3 Mutation Associated Dilated Cardiomyopathy
Alexion Pharmaceuticals, Inc.6 enrolled10 locationsNCT07218887
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy
Non-obstructive Hypertrophic CardiomyopathyObstructive Cardiomyopathy, Hypertrophic
Lexicon Pharmaceuticals500 enrolled108 locationsNCT06481891
Recruiting
Phase 2
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc.165 enrolled67 locationsNCT07023614
Recruiting
Phase 2Phase 3
A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).
PediatricSymptomatic Obstructive Hypertrophic Cardiomyopathy
Cytokinetics55 enrolled38 locationsNCT06412666
Recruiting
Phase 3
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Intellia Therapeutics1,200 enrolled132 locationsNCT06128629
Recruiting
HCMR Re-Imaging Study
Hypertrophic Cardiomyopathy (HCM)
Christopher Kramer314 enrolled8 locationsNCT07054073
Recruiting
Recovery From ICUAW Following Severe Respiratory and Cardiac Failure
Respiratory FailureCardiac FailureAcute Respiratory Distress Syndrome+4 more
Barts & The London NHS Trust100 enrolled1 locationNCT03753412
Recruiting
Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001
Transthyretin-Related (ATTR) Familial Amyloid CardiomyopathyTransthyretin-Related (ATTR) Familial Amyloid PolyneuropathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics72 enrolled4 locationsNCT05697861
Recruiting
Phase 2
Use of Bone Marrow Derived Stem Cell and G-CSF With Circulatory Assistance in the Treatment of DCM
Dilated Cardiomyopathy
Barts & The London NHS Trust20 enrolled1 locationNCT03572660
Recruiting
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy
Cardiomyopathy
Tenaya Therapeutics200 enrolled29 locationsNCT05112237
Recruiting
Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
Arrhythmogenic Right Ventricular Cardiomyopathy
Tenaya Therapeutics200 enrolled21 locationsNCT06311708
Recruiting
Not Applicable
Therapy to Maintain Remission in Dilated Cardiomyopathy
Heart FailureCardiomyopathiesHeart Diseases+1 more
Imperial College London50 enrolled1 locationNCT06091475
Recruiting
The SMARTER Cardiomyopathy Study
CardiomyopathiesHypertrophic CardiomyopathyDilated Cardiomyopathy
Imperial College London1,000 enrolled2 locationsNCT05750147