Phase 2 Obesity Clinical Trials
125 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 125 trials
Recruiting
Phase 2
A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight
Overweight or Obesity and Elevated Liver Fat
Amgen180 enrolled23 locationsNCT07441252
Recruiting
Phase 2
Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment
ObesityWeight LossEating+1 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)148 enrolled1 locationNCT00739362
Recruiting
Phase 2
A Phase 2 Study to Evaluate the Pharmacodynamics, Safety and Tolerability of BGE-102 in Participants With Obesity and Cardiovascular Risk Factors
Obesity and Cardiovascular Risk
BioAge Labs, Inc.160 enrolled13 locationsNCT07656727
Recruiting
Phase 2
Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity
ObesityOverweight
Kailera320 enrolled23 locationsNCT07497880
Recruiting
Phase 2
Phentermine's Impact on Treatment in Teens
Childhood Obesity
Russell McCulloh, MD240 enrolled2 locationsNCT07282340
Recruiting
Phase 1Phase 2
A Study to Evaluate ALN-2232 in Participants With Obesity
Obesity
Alnylam Pharmaceuticals156 enrolled1 locationNCT07463846
Recruiting
Phase 2
A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)
ObesityBody WeightOverweight+5 more
Pfizer872 enrolled48 locationsNCT07575932
Recruiting
Phase 2Phase 3
Weight Management Plus LNG-IUS/Megestrol Acetate in Endometrial Atypical Hyperplasia
Overweight and ObesityAtypical Endometrial HyperplasiaFertility Issues
Xiaojun Chen172 enrolled1 locationNCT05316493
Recruiting
Phase 2
A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes
ObesityDiabetes Mellitus, Type 2Overweight
Eli Lilly and Company200 enrolled42 locationsNCT07215559
Recruiting
Phase 2
Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity
ObesityAcute Lymphoblastic Leukemia
St. Jude Children's Research Hospital20 enrolled1 locationNCT07228741
Recruiting
Phase 1Phase 2
A Phase 1/2a Study of WVE-007 in Adults Living With Overweight or Obesity
Overweight and Obesity
Wave Life Sciences USA, Inc.296 enrolled6 locationsNCT06842186
Recruiting
Phase 1Phase 2
A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes
Obesity and Obesity-related Medical Conditions
Pfizer381 enrolled1 locationNCT06924320
Recruiting
Phase 2
EXploratory Study on Postprandial Energy Metabolism
Obesity and OverweightModerately Obese
Lallemand Health Solutions66 enrolled1 locationNCT06786052
Recruiting
Phase 2
Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV
Obesity and OverweightHIVChronic Inflammation
University of Hawaii12 enrolled1 locationNCT06935838
Recruiting
Phase 2
A Study of CS060380 Tablets in Patients With MASH and Obesity
Metabolic dysfunction-associated steatohepatitis (MASH)Obesity
Cascade Pharmaceuticals, Inc120 enrolled12 locationsNCT07466017
Recruiting
Phase 2
Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV
FrailtyAgingHIV-1-infection+2 more
Massachusetts General Hospital100 enrolled2 locationsNCT06554717
Recruiting
Phase 2
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
ObesityOverweight
Eli Lilly and Company1,481 enrolled53 locationsNCT06143956
Recruiting
Phase 1Phase 2
A Trial to Learn How Safe AZD9550 Monotherapy and Combined With AZD6234 is in People With or Without Type 2 Diabetes Who Are Living With Obesity and Overweight
Overweight and Obesity
AstraZeneca160 enrolled15 locationsNCT06151964
Recruiting
Phase 1Phase 2
The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function
ObesityMetabolic Syndrome
Vanderbilt University Medical Center74 enrolled1 locationNCT05972564
Recruiting
Phase 2
Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US
Overweight or Obesity
Regeneron Pharmaceuticals120 enrolled3 locationsNCT07431086