Early Phase 1 Obesity Clinical Trials

16 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 116 of 16 trials

Recruiting
Early Phase 1

Tirzepatide in Obesity-Driven Endometrial Cancer

Endometrial CancerObesity
UNC Lineberger Comprehensive Cancer Center20 enrolled1 locationNCT07065552
Recruiting
Early Phase 1

Regional Lipolysis Insulin Regulation

Obesity
Mayo Clinic48 enrolled1 locationNCT06392854
Recruiting
Early Phase 1

Insulin Regulation of Lipolysis and Lipolysis Proteins

Obesity
Mayo Clinic64 enrolled1 locationNCT03866408
Recruiting
Early Phase 1

A Trial of HRS-5817 in Obese Participants

Obesity
Atridia Pty Ltd.40 enrolled1 locationNCT07238647
Recruiting
Early Phase 1

Regional Lipolysis and Adipocyte Lipolysis Protein Stimulation

Obesity
Mayo Clinic24 enrolled1 locationNCT06416969
Recruiting
Early Phase 1

Evaluation of Milk Polar Lipids in Dyslipidemic Adults With Abdominal Obesity

ObesityDyslipidemias
University of Connecticut130 enrolled1 locationNCT05700916
Recruiting
Early Phase 1

Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues

ObesityMultiple SclerosisLong COVID+4 more
University of Chicago30 enrolled1 locationNCT06171152
Recruiting
Early Phase 1

Cardiovascular Effects of Angiotensin-(1-7) in Obesity Hypertension

ObesityHypertension
Milton S. Hershey Medical Center52 enrolled1 locationNCT06482853
Recruiting
Early Phase 1

Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)

ObesityHypertension
University of Texas Southwestern Medical Center100 enrolled1 locationNCT04838678
Recruiting
Early Phase 1

Akkermansia Muciniphilia and Metabolic Side Effects of ADT

Prostate CancerObesityMetabolic Syndrome+4 more
Western University30 enrolled1 locationNCT05802121
Recruiting
Early Phase 1

Social Determinants of Sleep and Obesity

ObesityPhysical InactivitySedentary Behavior+1 more
University of Minnesota90 enrolled1 locationNCT05698693
Recruiting
Early Phase 1

Effect of Tirzepatide on Markers of MASLD in Patients With Obesity

ObesityMASLD
University of New Mexico8 enrolled1 locationNCT06934642
Recruiting
Early Phase 1

Induction of Labor in Morbidly Obese Patients

PregnancyMorbid Obesity
University of Maryland, Baltimore162 enrolled1 locationNCT06199154
Recruiting
Early Phase 1

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

ObesityHealthyVasodilation
University of Missouri-Columbia72 enrolled1 locationNCT05219799
Recruiting
Early Phase 1

Randomized Control Trial of Sleeve Gastrectomy with Tirzepatide in Maximizing Weight Loss

Obesity and Obesity-related Medical Conditions
Nicholas Skertich42 enrolled1 locationNCT06734273
Completed
Early Phase 1

The effect of diet and portion size on oral fatty acid sensitivity

ObesityAnxietyDiet
Associate Professor Russell Keast120 enrolled1 locationACTRN12611000679987