Phase 2 Older Clinical Trials

16 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 116 of 16 trials

Recruiting
Phase 2Phase 3

(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis

Indolent Systemic MastocytosisSmoldering Systemic Mastocytosis
Blueprint Medicines Corporation534 enrolled64 locationsNCT04910685
Recruiting
Phase 2

Iberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple Myeloma

Smoldering Plasma Cell Myeloma
Emory University68 enrolled1 locationNCT04776395
Recruiting
Phase 2

A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma

Smoldering Multiple Myeloma (SMM)Monoclonal Gammopathy of Undetermined Significance (MGUS)
Regeneron Pharmaceuticals116 enrolled20 locationsNCT06140524
Recruiting
Phase 2

Fortifying Healthy Behaviors, Optimizing Medical Therapies and Enhancing Cognitive Function in Older Adults-pilot Study

Older AdultsCognitive DeclineAging+1 more
Washington University School of Medicine20 enrolled1 locationNCT07000734
Recruiting
Phase 2

Efficacy of Trazodone to Treat Insomnia in Older Adults (TRADITION Study)

Older PeopleDrug TherapyInsomnia Chronic
Centre hospitalier de l'Université de Montréal (CHUM)40 enrolled1 locationNCT06983080
Recruiting
Phase 2

Impact of Intensive Treatment of SBP on Brain Perfusion, Amyloid, and Tau (IPAT Study)

HypertensionSubjective Cognitive DeclineCognitively Normal Older Adults+1 more
Rong Zhang180 enrolled1 locationNCT05331144
Recruiting
Phase 1Phase 2

The TG01 Study With TG01/QS-21 Vaccine in Patients With High-risk Smouldering Multiple Myeloma and Multiple Myeloma

Multiple MyelomaSmoldering Multiple Myeloma
Oslo University Hospital20 enrolled1 locationNCT05841550
Recruiting
Phase 2

Carbon Ion Radiotherapy for Locally Advanced Lung Cancer in Elderly Patients

Radiotherapy Side EffectNon-small Cell Lung CancerOlder People+1 more
Jian Chen29 enrolled1 locationNCT06311981
Recruiting
Phase 2

Selinexor for the Treatment of Intermediate and High-Risk Smoldering Multiple Myeloma

Smoldering Multiple Myeloma
University of Rochester15 enrolled1 locationNCT05597345
Recruiting
Phase 2

Ciltacabtagene Autoleucel in High-Risk Smoldering Multiple Myeloma

High Risk Smoldering Multiple Myeloma
PETHEMA Foundation20 enrolled1 locationNCT06574126
Recruiting
Phase 2

Use of Elranatamab in Patients With High-risk Smoldering Multiple Myeloma

Smoldering Multiple Myeloma
Stichting European Myeloma Network50 enrolled25 locationsNCT06183489
Recruiting
Phase 2

Curcumin and Piperine in Patients on Surveillance for Monoclonal Gammopathy, Smoldering Myeloma or Prostate Cancer

Prostate CancerMultiple MyelomaMonoclonal Gammopathy of Undetermined Significance+1 more
University of Rochester40 enrolled1 locationNCT04731844
Completed
Phase 2

The effect of resveratrol in red wine on cognitive function in older adults: Preliminary study

Absorption rates of resveratrolCognitive function in older adults
Swinburne University of Technology20 enrolled1 locationACTRN12611001288910
Completed
Phase 2

The effect of transdermal testosterone gel300mcg daily on cognitive performance in older postmenopausal women: a placebo controlled trial over 26 weeks

cognition in older postmenopausal women
Monash University120 enrolled1 locationACTRN12609000981224
Recruiting
Phase 2

Amway - workability trial

Physical capacity and work ability of older workers
The University of Sydney20 enrolled1 locationACTRN12606000323527
Completed
Phase 2Phase 3

Hospital versus home-based pre-discharge occupational therapy consultations for older people: a pilot study

Hospitalised older people who will return to community living post-discharge.
Rehabilitation Studies Unit, University of Sydney10 enrolled1 locationACTRN12606000213549