Peripheral Vascular Disease Clinical Trials

22 recruitingLast updated: May 13, 2026

There are 22 actively recruiting peripheral vascular disease clinical trials across 13 countries. Studies span Not Applicable, Phase 3, Early Phase 1, Phase 1, Phase 2. Top locations include Chicago, Illinois, United States, Richmond, Virginia, United States, München, Germany. Updated daily from ClinicalTrials.gov.


Peripheral Vascular Disease Trials at a Glance

22 actively recruiting trials for peripheral vascular disease are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Not Applicable with 9 trials, with the heaviest enrollment activity in Chicago, Richmond, and München. Lead sponsors running peripheral vascular disease studies include Northwestern University, Virginia Commonwealth University, and University of Nebraska.

Browse peripheral vascular disease trials by phase

Treatments under study

About Peripheral Vascular Disease Clinical Trials

Looking for clinical trials for Peripheral Vascular Disease? There are currently 12 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Peripheral Vascular Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Peripheral Vascular Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 22 trials

Recruiting
Not Applicable

Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1

Peripheral Vascular Diseases
Virginia Commonwealth University720 enrolled1 locationNCT04916327
Recruiting

Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature

Peripheral Vascular Diseases
Boston Scientific Corporation5,000 enrolled79 locationsNCT04674969
Recruiting
Phase 3

SMART Exercise for PAD

Peripheral Arterial DiseaseAgingWalking, Difficulty+1 more
Northwestern University210 enrolled3 locationsNCT06032065
Recruiting
Not Applicable

ENhancing Exercise With LIGHT to Improve Functioning in PAD

AgingWalking, DifficultyPeripheral Artery Disease+1 more
Northwestern University32 enrolled1 locationNCT06399900
Recruiting
Phase 2

Fisetin to Reduce Senescence and Mobility Impairment in PAD

ClaudicationPeripheral Arterial DiseaseAging+2 more
Northwestern University34 enrolled1 locationNCT06399809
Recruiting
Not Applicable

EVERO Drug-coated Balloon (DCB) Randomized Trial

Peripheral Arterial DiseasePeripheral Vascular Disease
Cook Research Incorporated410 enrolled1 locationNCT07144150
Recruiting
Not Applicable

Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 3

Peripheral Vascular Diseases
Virginia Commonwealth University240 enrolled1 locationNCT04916340
Recruiting

Observing the Role of Inflammation in Peripheral Artery Disease and Its Impact on Heart and Mobility Health: PANACEA-O.

Peripheral Vascular Disease
Cardiology Research UBC50 enrolled1 locationNCT07500610
Recruiting
Phase 3

A Contrast Medium Sparing Strategy Using Automated CO2 Injection During PVI for Prevention of Major Adverse Kidney Events (MAKE)

Kidney DiseasesPeripheral Vascular Diseases
University of Leipzig1,960 enrolled11 locationsNCT06656988
Recruiting

MRI Guided Management of Occlusive Peripheral Arterial Disease

Peripheral Vascular Diseases
The Methodist Hospital Research Institute175 enrolled1 locationNCT06782100
Recruiting
Not Applicable

Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 2

Peripheral Vascular Diseases
Virginia Commonwealth University360 enrolled1 locationNCT04922762
Recruiting
Early Phase 1

Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease

Peripheral arterial occlusive diseasePeripheral Arterial DiseasePeripheral Vascular Diseases+1 more
University of Nebraska20 enrolled1 locationNCT06319339
Recruiting
Not Applicable

Leg Exercise Assistive Paddling (LEAP) Therapy for Peripheral Artery Disease

Peripheral Arterial DiseasePeripheral Artery DiseasePeripheral Vascular Disease+1 more
University of Nebraska24 enrolled1 locationNCT06389149
Recruiting

Safety, Performance and Usability of BALT Medical Devices: The EVIDENCE Post Marketing Clinical Follow-up Platform

Acute Ischemic StrokeBrain Arterial DiseaseIntracranial Aneurysm+4 more
Balt Extrusion10,000 enrolled12 locationsNCT04927156
Recruiting
Not Applicable

Randomized Controlled Trial of Alert-Based Computerized Decision Support for Patients With Peripheral Artery Disease Not Prescribed Lipid-Lowering Therapy

DyslipidemiasPeripheral Vascular DiseasesPeripheral Artery Disease
Brigham and Women's Hospital400 enrolled1 locationNCT06300450
Recruiting
Phase 3

Improving Mobility After Revascularization in Peripheral Artery Disease

intermittent claudicationMobility LimitationPeripheral Artery Disease+2 more
Northwestern University386 enrolled7 locationsNCT06686121
Recruiting
Not Applicable

Far Red Light to Improve Functioning in PAD

AgingWalking, DifficultyPeripheral Artery Disease+1 more
Northwestern University32 enrolled2 locationsNCT06165016
Recruiting

The Mechanical Characterisation of Human Saphenous and Popliteal Vein

Peripheral Vascular Diseases
University Hospital of Limerick50 enrolled1 locationNCT04016649
Recruiting
Phase 1

The Effects of ATLAS Therapy on Nitric Oxide Bioavailability in Patients With Intermittent Claudication

Peripheral Vascular DiseasesPeripheral Artery DiseaseClaudication, Intermittent
Louis Messina10 enrolled1 locationNCT04800692
Recruiting

Vascular Regenerative Cell Exhaustion in Adults with Peripheral Artery Disease (PAD-VRCE)

Cardiovascular DiseaseType 2 DiabetesPeripheral Vascular Diseases+1 more
Canadian Medical and Surgical Knowledge Translation Research Group40 enrolled2 locationsNCT06626646