Primary Prevention Clinical Trials

6 recruiting

Primary Prevention Trials at a Glance

13 actively recruiting trials for primary prevention are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in Bern, Gyeonggi-do, and Brest. Lead sponsors running primary prevention studies include Insel Gruppe AG, University Hospital Bern, Saint Vincent's Hospital, Korea, and China Medical University, China.

Browse primary prevention trials by phase

Treatments under study

About Primary Prevention Clinical Trials

Looking for clinical trials for Primary Prevention? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Primary Prevention trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Primary Prevention clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 113 of 13 trials

Recruiting

A Hospital-Based Registry of Preventive Cardiology Clinics

Cardiovascular MorbidityCardiovascular Risk AssesmentPrimary Prevention CVD
National Institute of Cardiovascular Diseases, Pakistan10,000 enrolled1 locationNCT06503341
Recruiting
Not Applicable

Cardioverter DefIbriIlator PlacEMent for priMary Prevention of Sudden cArdiac Death in Patients Older Than 70 Years

Heart FailurePrimary Prevention of Sudden Cardiac DeathImplantable Cardioverter Defibrillator
Assistance Publique - Hôpitaux de Paris730 enrolled19 locationsNCT05373940
Recruiting
Not Applicable

A Tailored, Optimised, and Person-centred Programme to Promote Lifestyle Modification in People With Metabolic Syndrome

Metabolic SyndromePrimary Prevention of Atherosclerotic Cardiovascular Disease
The University of Hong Kong152 enrolled1 locationNCT06793930
Recruiting
Not Applicable

Health Behavior Change in High-Risk Colorectal Cancer Individuals

Colorectal NeoplasmsHealth BehaviorPrimary Prevention/Methods
China Medical University, China80 enrolled1 locationNCT07262840
Recruiting
Phase 4

GUIDE-CAC: Statin-Ezetimibe Without Aspirin vs. Statin Monotherapy With Aspirin in High Coronary Calcification

Vascular CalcificationPrimary Prevention
Asan Medical Center7,435 enrolled1 locationNCT06722521
Recruiting
Not Applicable

Polygenic Risk Score for Optimizing Primary Prevention in Intermediate-Risk Populations

Primary Prevention of Cardiovascular Disease
University of Bern204 enrolled2 locationsNCT07039123
Recruiting
Not Applicable

Comparison of Intensive Versus Standard Care & Education for Dyslipidemia in Hypertension and Diabetes Patients

Diabetes MellitusHypertensionDyslipidemia+1 more
Saint Vincent's Hospital, Korea348 enrolled1 locationNCT07045623
Recruiting
Phase 4

Clinical Comparison of Low-dose Rosuvastatin Plus Ezetimibe Combination Therapy and High-dose Rosuvastatin Monotherapy in Patients With Minimal to Intermediate Coronary Artery Disease Without Percutaneous Coronary Intervention

Coronary Artery DiseaseDyslipidemiasPrimary Prevention
Saint Vincent's Hospital, Korea6,356 enrolled1 locationNCT06186037
Recruiting
Not Applicable

Non-pharmacological Prevention of POD in Frailty Elderly Undergoing Elective Surgery Applied by Nursing Teams

FrailtyPostoperative DeliriumFrail Elderly Syndrome+1 more
Pontificia Universidad Catolica de Chile400 enrolled1 locationNCT05993754
Recruiting
Not Applicable

Role of Coronary CTA on Lipid Management and Risk Factors Control in an Asymptomatic Chinese Population

Cardiovascular Risk FactorsAdherence, MedicationPrimary Prevention+1 more
Zhang longjiang,MD3,400 enrolled1 locationNCT05725096
Recruiting
Not Applicable

FIT FIRST Teen - School Intervention Study

Primary Prevention
University of Southern Denmark912 enrolled1 locationNCT06615791
Recruiting
Not Applicable

STREAM Trial - Subclinical Atherosclerosis

Statin Treatment for Primary Prevention
Insel Gruppe AG, University Hospital Bern500 enrolled1 locationNCT05482399
Recruiting
Not Applicable

STREAM Trial - Biomarker

Statin Treatment for Primary Prevention
Insel Gruppe AG, University Hospital Bern500 enrolled1 locationNCT05482386