Phase 3 PROC Clinical Trials

21 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 21 trials

Recruiting
Phase 2Phase 3

Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy

EsophagectomyEsophageal Cancer SurgeryDelayed Gastric Emptying Following Procedure+4 more
The Cleveland Clinic170 enrolled1 locationNCT06721520
Recruiting
Phase 3

A Study to Investigate Bowel Cleansing With PLENVU® Compared to Sodium Picosulfate in Participants Aged 1 to < 18 Years of Age in Preparation for Colonoscopy

Bowel Cleansing Prior to Clinical Procedures
Norgine212 enrolled40 locationsNCT07218523
Recruiting
Phase 3

Pharmacokinetics, Safety, and Tolerability Study of GOPRELTO® Nasal Solution and NUMBRINO™ Nasal Solution

ENT DisorderNasal ProceduresNasal Anesthesia+1 more
Noden Pharma40 enrolled4 locationsNCT04792034
Not Yet Recruiting
Phase 3

Intranasal Dexmedetomidine for Pain Reduction during Retinopathy of Prematurity Screening: A Randomised Controlled Trial

Procedural Pain
Renee Muirhead- Mater Mothers Hospital82 enrolled1 locationACTRN12625001307493
Recruiting
Phase 3

Remimazolam vs. Midazolam for Sedation and Cognitive Outcomes in Orthopedic Surgery

Postoperative Pain ManagementPostoperative Cognitive DysfunctionHip Fracture+1 more
Romanian Society for Enteral and Parenteral Nutrition120 enrolled1 locationNCT07113483
Recruiting
Phase 2Phase 3

Clonidine in Ultrasound-guided Rectus Sheath Block for Outpatient Umbilical Hernioplasty

Pain, PostoperativeHernia, UmbilicalClonidine+2 more
Universidade Federal do Rio de Janeiro62 enrolled1 locationNCT07062497
Recruiting
Phase 2Phase 3

Human Penile Allotransplantation

Wounds and InjuriesAmputationAmputation, Traumatic+6 more
Johns Hopkins University60 enrolled1 locationNCT02395497
Not Yet Recruiting
Phase 3

Penthrox vs nitrous oxide for painful emergency medicine procedures

Painful emergency medicine procedures
Eastern Health198 enrolled1 locationACTRN12624001117505
Recruiting
Phase 3

Autofluorescence and Indocyanine Green to Avoid Hypocalcemia After Thyroidectomy

Thyroid DiseaseHypoparathyroidism Postprocedural
Onze Lieve Vrouw Hospital300 enrolled1 locationNCT05117853
Recruiting
Phase 2Phase 3

Preoperative Paravertebral Block in Cancer Surgery of the Lung

Thoracic NeoplasmChronic Pain Post-ProceduralAcute Post-thoracotomy Pain+1 more
Guy's and St Thomas' NHS Foundation Trust100 enrolled1 locationNCT04209868
Recruiting
Phase 3

Effects of Digital Therapeutic in Whole Process Management of Lung Cancer

Application of Digital Therapeutic in Lung Cancer Whole Process Management
Sun Yat-sen University900 enrolled1 locationNCT06230445
Recruiting
Phase 3

PROMPT: PROcedural sedation vs Methoxyflurane a Prospective cohorT Study.

Interventional Radiology procedural analgesia
South Western Sydney Local Health District Human Research Ethics Committee150 enrolled1 locationACTRN12623001127695
Recruiting
Phase 3

Comparisons of Metabolic Effect of Sleeve Gastrectomy With Duodenojejunal Bypass and Sleeve Gastrectomy (MEDUSA): A Multicenter Randomized Controlled Trial

Bariatric SurgeryDiabetes Mellitus, Type 2Surgical Procedures, Operative+1 more
Seoul National University Bundang Hospital130 enrolled1 locationNCT05211375
Terminated
Phase 3

The effects of intranasal oxytocin on emotion processing and carer burden in individuals diagnosed with frontotemporal dementia

Frontotemporal DementiaEmotion Processing
The University of Sydney1 enrolled1 locationACTRN12618001807246
Not Yet Recruiting
Phase 2Phase 3

The safety and efficacy of intranasal ketamine delivery for sedation of children in the emergency department. Is a needle-free approach to the care of children in the emergency department, practical and attainable?

Sedation procedures in children
The Townsville Hospital and Health Service652 enrolled4 locationsACTRN12616000399493
Recruiting
Phase 3

Double blind, placebo controlled randomised trial assessing the efficacy of endothelin-1 receptor antagonism in the prevention of microvascular injury in patients with non-ST elevation acute coronary syndrome (NSTEACS) undergoing percutaneous coronary intervention: the ENDORA-PCI trial

Peri-procedural myocardial injury/infarctionNon-ST elevation acute coronary syndrome (NSTEACS)
Prince of Wales Hospital52 enrolled1 locationACTRN12615000709549
Completed
Phase 2Phase 3

Magnetic Resonance Imaging (MRI) guided audiovisual biofeedback for precise lung cancer radiotherapy

Lung tumour motion consistency throughout medical imaging and radiotherapy proceduresLung Cancer
University of Sydney15 enrolled1 locationACTRN12615000163505
Completed
Phase 3

Pharmacokinetics of 0.25% levobupivacaine with adrenaline following caudal epidural administration in children

Children undergoing elective sub-umbilical surgical procedures for which caudal epidural analgesia is indicated.
Royal Children's Hospital60 enrolled1 locationACTRN12609000845235
Completed
Phase 3

Pharmacokinetics of 0.25% levobupivacaine with adrenaline and clonidine following caudal epidural administration in children

Children undergoing elective sub-umbilical surgical procedures for which caudal epidural analgesia is indicated.
Royal Children's Hospital60 enrolled1 locationACTRN12609000668202
Not Yet Recruiting
Phase 3

Pharmacokinetics of 0.25% levobupivacaine with clonidine following caudal epidural administration in children

Children undergoing elective sub-umbilical surgical procedures for which caudal epidural analgesia is indicated.
Royal Children's Hospital50 enrolled1 locationACTRN12609000126213