Systemic Inflammatory Response Clinical Trials

14 recruitingLast updated: May 11, 2026

There are 14 actively recruiting systemic inflammatory response clinical trials across 10 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 1. Top locations include Florence, Italy, Edmonton, Alberta, Canada, Empoli, Firenze, Italy. Updated daily from ClinicalTrials.gov.


Systemic Inflammatory Response Trials at a Glance

14 actively recruiting trials for systemic inflammatory response are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 3 trials, with the heaviest enrollment activity in Florence, Edmonton, and Empoli. Lead sponsors running systemic inflammatory response studies include Careggi Hospital, Federal University of São Paulo, and Assistance Publique - Hôpitaux de Paris.

Browse systemic inflammatory response trials by phase

Treatments under study

About Systemic Inflammatory Response Clinical Trials

Looking for clinical trials for Systemic Inflammatory Response? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Systemic Inflammatory Response trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Systemic Inflammatory Response clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 114 of 14 trials

Recruiting
Not Applicable

Improving Health Outcomes With Kefir

Cardiovascular DiseasesDiabetes Mellitus, Type 2Systemic Inflammatory Response
University of Alberta156 enrolled1 locationNCT06695221
Recruiting

Determinants of Vascular Leakage During Systemic Inflammatory Response Syndrome

Systemic Inflammatory Response Syndrome
Assistance Publique - Hôpitaux de Paris180 enrolled2 locationsNCT05663216
Recruiting

Modulation of Molecular Fingerprinting in Pediatric Sepsis

Systemic Inflammatory Response Syndrome
Phoenix Children's Hospital50 enrolled2 locationsNCT02055105
Recruiting
Not Applicable

The Effect of Pectin Supplementation on Geriatric With Frailty: A Randomised Placebo-Controlled Dietary Intervention Study

pre frailtyFrailtyDiet+3 more
University of Nottingham30 enrolled1 locationNCT06955975
Recruiting

Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate?

SepsisSystemic Inflammatory Response SyndromeInfection, Bacterial+3 more
Michigan State University2,500 enrolled2 locationsNCT01904188
Recruiting

Extracorporeal Blood Purification Therapy in Critically Ill Patients (GlobalARRT)

SepsisSystemic Inflammatory Response SyndromeAcute Kidney Injury+1 more
Careggi Hospital1,000 enrolled1 locationNCT04580680
Recruiting

Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan Failure

SepsisSystemic Inflammatory Response SyndromeAcute Kidney Injury+1 more
Careggi Hospital1,000 enrolled15 locationsNCT04033224
Recruiting
Phase 1Phase 2

Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Control the Immune Hyperactivation Associated With COVID-19 and/or Acute Respiratory Distress Syndrome (THYTECH2)

Systemic Inflammatory Response Syndrome
Hospital General Universitario Gregorio Marañon24 enrolled1 locationNCT06052436
Recruiting
Phase 2

Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock

SepsisPathologic ProcessesInfections+4 more
Ottawa Hospital Research Institute296 enrolled2 locationsNCT05969275
Recruiting
Not Applicable

Protective Effect of Sivelestat Against Negative Pulmonary Function and Organ Dysfunction After Cardiovascular Surgery (PANDA VI)

Systemic Inflammatory Response SyndromeAortic DissectionCardiovascular Diseases (CVD)
Nanjing Medical University500 enrolled2 locationsNCT06195267
Recruiting
Phase 2

PBM as Strategy to CABG Anemic Patients Bypass Graft (CABG)

Coronary DiseaseBleedingCoronary Artery Disease+5 more
Federal University of São Paulo120 enrolled1 locationNCT06542393
Recruiting
Phase 4

Hemodynamic Response to Angiotensin-II When Used as the Second Vasopressor Agent for Septic Shock

SepsisSystemic Inflammatory Response SyndromeSeptic Shock+1 more
Kingman Regional Medical Center50 enrolled1 locationNCT06122987
Recruiting

AOrtic Surgery: Systemic Inflammatory Response Versus Sepsis

InfectionsSystemic Inflammatory Response SyndromeThoracic Aortic Aneurysm+2 more
University Hospital Hradec Kralove60 enrolled1 locationNCT06028789
Recruiting
Phase 4

Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC

Non-small Cell Lung CancerOpioid UseAnesthesia+4 more
University of Crete70 enrolled1 locationNCT05172739