Early Phase 1 Therapy Clinical Trials
24 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 24 trials
Recruiting
Early Phase 1
Exercise as an Immune Adjuvant for Allogeneic Cell Therapies
LymphomaLeukemiaCAR-T Cell Therapy+3 more
University of Arizona200 enrolled1 locationNCT06643221
Recruiting
Early Phase 1
Dual Target CAR-T Cell Treatment for Refractory Systemic Lupus Erythematosus (SLE) Patients
CAR-T Cell Therapy
RenJi Hospital18 enrolled1 locationNCT05858684
Recruiting
Early Phase 1
Single Arm Romiplostim to Prevent CIT
Ewings SarcomaChemotherapy Induced Thrombocytopenia
Children's Hospital Medical Center, Cincinnati26 enrolled2 locationsNCT07048249
Recruiting
Early Phase 1
Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer
Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8+20 more
Ohio State University Comprehensive Cancer Center50 enrolled1 locationNCT05417308
Recruiting
Early Phase 1
Efficacy and Safety Study of DC-CIK Cell Therapy Combined With Epaloliposide, Vortexil, and Regorafenib as Third-line Treatment for Advanced Colorectal Cancer.
Colorectal, CancerDC-CIK TreatmentRegorafenib+2 more
JIANG LONGWEI14 enrolled1 locationNCT07343791
Recruiting
Early Phase 1
Intraoral Hypothermia Device for Preserving Taste During Radiation
Head and Neck CancerRadiation TherapyTaste Dysfunction
Henry Ford Health System15 enrolled1 locationNCT06579248
Recruiting
Early Phase 1
Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer
Breast CancerTriple-Negative Breast CancerHER2-positive Breast Cancer+3 more
Alison Stopeck30 enrolled1 locationNCT06220214
Recruiting
Early Phase 1
Pembrolizumab and Lenvatinib for the Treatment of Advanced, Unresectable, or Metastatic Gastroesophageal Adenocarcinoma
Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IV Gastric Cancer AJCC v8+30 more
M.D. Anderson Cancer Center15 enrolled1 locationNCT05041153
Recruiting
Early Phase 1
Exploring the Benefit of Topical Capsaicin in Treating Pain From Chemo-induced Peripheral Neuropathy: a Longitudinal Single Center Pilot Study
Peripheral Neuropathy Due to Chemotherapy
M.D. Anderson Cancer Center20 enrolled1 locationNCT06744816
Recruiting
Early Phase 1
A Study of TIL in Advanced Solid Tumors (DFGD)
Advanced Solid TumorTreatment Side EffectsEffects of Immunotherapy+1 more
Shanghai Juncell Therapeutics30 enrolled1 locationNCT06488950
Recruiting
Early Phase 1
A Study of GC101 TIL in Advanced Breast Cancer (10hospital)
Breast CancerAdvanced Breast CancerTreatment Side Effects+1 more
Shanghai Juncell Therapeutics50 enrolled1 locationNCT05142475
Recruiting
Early Phase 1
A Study of GC101 TIL in Advanced Melanoma (10hospital)
Advanced MelanomaTreatment Side EffectsEffects of Immunotherapy+1 more
Shanghai Juncell Therapeutics50 enrolled1 locationNCT05098184
Recruiting
Early Phase 1
A Study of GC201 TIL in Advanced Gynecologic Tumors (10hospital)
Treatment Side EffectsEffects of ImmunotherapyAdvanced Gynecologic Tumors+1 more
Shanghai Juncell Therapeutics50 enrolled1 locationNCT05098171
Recruiting
Early Phase 1
A Study of GC101 TIL in Advanced Hepatobiliary-Pancreatic Cancers (10hospital)
Treatment Side EffectsEffects of ImmunotherapyTumor Infiltrating Lymphocyte+2 more
Shanghai Juncell Therapeutics50 enrolled1 locationNCT05098197
Recruiting
Early Phase 1
TC-D101 Cell Therapy for Patients With DLL3-Positive SCLC
Small Cell Lung Cancer ( SCLC )CAR-T Cell Therapy
TCRCure Biopharma Ltd.24 enrolled1 locationNCT07246304
Recruiting
Early Phase 1
Clinical Study of mRNA Vaccine Combined With PD-1 Inhibitor as Adjuvant Therapy for Postoperative Pancreatic Cancer
Pancreatic Cancer ResectableChemotherapy-intolerant
Ruijin Hospital20 enrolled1 locationNCT06496373
Recruiting
Early Phase 1
Neuroprotective Potential of Cannabidiol (CBD) in Preventing Oxaliplatin (Ox)-Induced Neuropathy
Metastatic Colorectal Cancer (CRC)Oxaliplatin Induced Peripheral Neuropathy in Cancer PatientsPeripheral Neuropathy Due to Chemotherapy
Fox Chase Cancer Center30 enrolled1 locationNCT07167446
Recruiting
Early Phase 1
Pharmacokinetic Study of Topical Phenylephrine
Chemotherapy-induced AlopeciaChemotherapy Side Effects
Applied Biology, Inc.24 enrolled1 locationNCT07033845
Recruiting
Early Phase 1
Supplemental Oxygen in Pulmonary Embolism (SO-PE)
Venous ThromboembolismPulmonary EmbolismMetabolomics+1 more
Massachusetts General Hospital80 enrolled1 locationNCT05891886
Recruiting
Early Phase 1
Gene Expression Changes In Young and Geriatric Skin
AgingUVB Phototherapy BurnInsulin-like Growth Factor 1
Wright State University24 enrolled1 locationNCT03932162