Phase 3 Thyroid Clinical Trials

38 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 38 trials

Recruiting
Phase 3

A Phase 3 Randomized Clinical Trial to Investigate the Safety and Efficacy of Palopegteriparatide at Doses Greater Than 30 μg/Day in Adult Participants With Hypoparathyroidism

HypoparathyroidismEndocrine System DiseasesParathyroid Diseases
Ascendis Pharma Bone Diseases A/S36 enrolled2 locationsNCT07081997
Recruiting
Phase 2Phase 3

Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors

Primary HyperparathyroidismParathyroid CancerMultiple Endocrine Neoplasias+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)193 enrolled1 locationNCT07444723
Recruiting
Phase 3

Open-Label Extension Study of MHB018A in Subjects With Thyroid Eye Disease

Thyroid Eye Disease (TED)
Minghui Pharmaceutical (Hangzhou) Ltd258 enrolled1 locationNCT07262476
Recruiting
Phase 3

MHB018A Treatment in Patients With Active Thyroid Eye Disease

Thyroid Associated Ophthalmopathies
Minghui Pharmaceutical (Hangzhou) Ltd108 enrolled1 locationNCT06989918
Recruiting
Phase 3

MHB018A Treatment in Patients With Chronic Thyroid Eye Disease

Thyroid Eye Disease (TED)
Minghui Pharmaceutical (Hangzhou) Ltd150 enrolled1 locationNCT07257185
Recruiting
Phase 3

A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis

Secondary Hyperparathyroidism
Amgen24 enrolled23 locationsNCT03969329
Recruiting
Phase 3

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

Refractory Differentiated Thyroid Gland Carcinoma
ECOG-ACRIN Cancer Research Group264 enrolled112 locationsNCT06475989
Recruiting
Phase 3

Contribution of ICG Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy

Thyroid Diseases
University Hospital, Brest242 enrolled1 locationNCT04785443
Recruiting
Phase 2Phase 3

Novel Approaches to the Treatment of Hypothyroidism

Hypothyroidism
UConn Health90 enrolled1 locationNCT06731764
Recruiting
Phase 3

Selective Neck Dissection Versus Modified Neck Dissection in PTC

Thyroid Cancer
Fudan University250 enrolled1 locationNCT06554652
Recruiting
Phase 3

Adjuvant Radiotherapy in High Risk Locally Advanced DTC

Thyroid Cancer
Fudan University124 enrolled1 locationNCT06558981
Recruiting
Phase 3

A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis

Chronic Kidney DiseaseSecondary Hyperparathyroidism
Amgen56 enrolled43 locationsNCT03633708
Recruiting
Phase 3

Preoperative Lugol's Solution in Graves' Disease and Toxic Nodular Goiter

Hyperthyroidism
Jan Calissendorff182 enrolled1 locationNCT04856488
Recruiting
Phase 3

CTR-FAPI-guided Precision Surgery for Newly Diagnosed MTC

Medullary Thyroid Carcinoma
Cancer Institute and Hospital, Chinese Academy of Medical Sciences150 enrolled1 locationNCT07383246
Recruiting
Phase 2Phase 3

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism
AbbVie2,800 enrolled139 locationsNCT06345339
Recruiting
Phase 3

A Study of AL2846 Capsule Versus Placebo in the Treatment of Advanced Radioiodine-Refractory Differentiated Thyroid Carcinoma

Thyroid Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.144 enrolled35 locationsNCT06860971
Recruiting
Phase 3

A Study to Assess the Efficacy and Safety of ZL-1109 in Chinese Participants With Active Thyroid Eye Disease

Thyroid Eye Disease (TED)
Zai Lab (Shanghai) Co., Ltd.99 enrolled27 locationsNCT07211776
Recruiting
Phase 3

Huaxi Tunnel Technique For Recurrent Laryngeal Nerve Exposure And Dissection In Thyroid Surgery

Patients Undergoing Open Thyroid Surgery
West China Hospital700 enrolled1 locationNCT07298616
Recruiting
Phase 2Phase 3

Trop2-targeted immunoPET Imaging of Solid Tumors

Liver CancerOvarian CancerCervical Cancer+11 more
RenJi Hospital400 enrolled1 locationNCT06851663
Recruiting
Phase 2Phase 3

DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers.

MelanomaOvarian NeoplasmsColorectal Neoplasms+3 more
Cancer Research UK30 enrolled16 locationsNCT05768178