Phase 2 Type 2 Diabetes Clinical Trials

39 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 39 trials

Recruiting
Phase 2

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

Type 2 DiabetesCortisol Excess
Sparrow Pharmaceuticals1,500 enrolled47 locationsNCT07296484
Recruiting
Phase 2

HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes

Type 2 Diabetes
Housey Healthcare ULC300 enrolled25 locationsNCT07546929
Recruiting
Phase 2

A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus (T2DM)
Alnylam Pharmaceuticals40 enrolled1 locationNCT07465224
Recruiting
Phase 1Phase 2

A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled20 locationsNCT06845202
Recruiting
Phase 2

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

Type 2 Diabetes
Eli Lilly and Company240 enrolled61 locationsNCT06897475
Recruiting
Phase 2

Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy

Type 2 Diabetes
Biomea Fusion Inc.60 enrolled14 locationsNCT07502508
Recruiting
Phase 2

Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic Targets

Type 2 Diabetes
Biomea Fusion Inc.60 enrolled15 locationsNCT07502495
Recruiting
Phase 2

A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 Diabetes

Type 2 Diabetes Mellitus
Hoffmann-La Roche240 enrolled51 locationsNCT07112872
Recruiting
Phase 2

Aleniglipron Phase 2 in Type 2 Diabetes Mellitus

ObesityWeight LossObese+1 more
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics50 enrolled17 locationsNCT07400588
Recruiting
Phase 1Phase 2

Triple Hypoglycemic Regimens In Patients With Newly Diagnosed Type 2 Diabetes Mellitus

Type 2 Diabetes
Second Affiliated Hospital of Guangzhou Medical University240 enrolled1 locationNCT07374328
Recruiting
Phase 2

A Study to Evaluate the Efficacy, Safety, and Tolerability of ASC30 Tablets in Participants With Type 2 Diabetes Mellitus

T2DM (Type 2 Diabetes Mellitus)
Ascletis Pharma (China) Co., Limited100 enrolled8 locationsNCT07321678
Recruiting
Phase 2

The Effect of Glycemic Control and of GLP-1 Receptor Agonism on Islet GLP-1 in People With Type 1 and Type 2 Diabetes

Type 1 DiabetesType 2 Diabetes
Mayo Clinic60 enrolled1 locationNCT06976619
Recruiting
Phase 2

Food Effect, Efficacy and Safety of MKP10241 in Healthy and Obese Adult Participants, With and Without Diabetes

ObesityType 2 Diabetes Mellitus (T2DM)Food Effect+1 more
Mankind Pharma Limited68 enrolled1 locationNCT07098663
Recruiting
Phase 2

A Study of HDM1005 in Participants With T2DM Not Controlled With Diet/Exercise or Metformin

Type 2 Diabetes
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.216 enrolled1 locationNCT07109700
Recruiting
Phase 2

Renal Mechanism of SGLT2 Inhibition

Type 2 DiabetesDiabetic Kidney Disease
University of Colorado, Denver40 enrolled2 locationsNCT05507892
Recruiting
Phase 1Phase 2

Polypill for Prevention of Cardiomyopathy

Type 2 DiabetesHigh Blood Pressure
University of Texas Southwestern Medical Center200 enrolled1 locationNCT06143566
Recruiting
Phase 2

Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.

Type 2 Diabetes Mellitus (T2DM)Type 1 Diabetes MellitusDiabetic Foot Ulcer+3 more
Estar Medical dba Medical Technologies, LTD30 enrolled2 locationsNCT06810726
Recruiting
Phase 2

Finerenone Treatment for Diabetic Cardiovascular Autonomic Neuropathy: the FibroCAN Study

Type 2 DiabetesDiabetic NeuropathiesCardiovascular Autonomic Neuropathy
Peter Rossing100 enrolled2 locationsNCT06906081
Recruiting
Phase 2

Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver DiseaseImpaired Glucose ToleranceType 2 Diabetes Mellitus+1 more
Yale University60 enrolled1 locationNCT05067621
Recruiting
Phase 2

Low-Dose Pioglitazone in Patients With NASH (AIM 2)

Type 2 Diabetes Mellitus (T2DM)Nonalcoholic Steatohepatitis
University of Florida166 enrolled1 locationNCT04501406