Phase 4 Type 2 Diabetes Clinical Trials

51 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 51 trials

Recruiting
Phase 4

Mechanism of SGLT2 Inhibition in the Kidney

Type 2 DiabetesDiabetic Kidney Disease
University of Michigan20 enrolled1 locationNCT06291155
Recruiting
Phase 4

SGLT2 Inhibitors on Coronary Atherosclerosis Progression Via Perivascular Adipose Tissue in Diabetes

AtherosclerosisType 2 Diabetes Mellitus (T2DM)Coronary Artery Disease
Junjie Yang144 enrolled2 locationsNCT07614230
Recruiting
Phase 4

Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy

Diabetic Foot UlcerFoot Ulcer Due to Type 2 Diabetes MellitusUlcer+4 more
Sequence LifeScience, Inc.350 enrolled1 locationNCT07086443
Recruiting
Phase 4

Enavogliflozin vs. Pioglitazone on Glucose and Atherosclerosis

Type 2 Diabetes
Seoul National University Bundang Hospital120 enrolled1 locationNCT06399835
Recruiting
Phase 4

Clopidogrel Versus Cilostazol on Vessels

AtherosclerosisType 2 Diabetes
Seoul National University Bundang Hospital120 enrolled1 locationNCT06402747
Recruiting
Phase 4

Effect of Early Combination Antihyperglycemic Treatment on Metabolic Control in Individuals With Type 2 Diabetes

Type 2 Diabetes Mellitus (T2DM)
University Medical Centre Ljubljana90 enrolled1 locationNCT06613854
Recruiting
Phase 4

Effect of GLP-1RA on Cardiac Autonomic Neuropathy in Type 2 Diabetes

Type 2 DiabetesDiabetes With Diabetic Autonomic Neuropathy (Diagnosis)
The First Affiliated Hospital with Nanjing Medical University60 enrolled1 locationNCT07558863
Recruiting
Phase 4

Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide

Diabetes Mellitus, Type 2DiabetesType 2 Diabetes+1 more
Stanford University104 enrolled2 locationsNCT06657209
Recruiting
Phase 4

Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes

Type 2 DiabetesSpinal Cord Injuries
Marzieh Salehi50 enrolled2 locationsNCT06706284
Recruiting
Phase 4

GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH

Genetic PredispositionType 2 DiabetesMetabolic Diseases
Massachusetts General Hospital125 enrolled1 locationNCT06003153
Recruiting
Phase 4

The Impact of Semaglutide Compared to Energy Restriction on Type 2 Diabetes

Type 2 Diabetes Mellitus (T2DM)SemaglutideCaloric Restriction
Second Affiliated Hospital of Nanchang University100 enrolled1 locationNCT07272343
Recruiting
Phase 4

iGlarLixi CGM Study in Chinese T2D Individuals After OADs

Type 2 Diabetes (T2D)
Sanofi678 enrolled1 locationNCT06671587
Recruiting
Phase 4

Glycemic Variability of Combination Therapies in T2DM

Type 2 Diabetes Mellitus (T2DM)
JW Pharmaceutical178 enrolled1 locationNCT07442006
Recruiting
Phase 4

A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers

Diabetic Foot UlcerDiabetic FootFoot Ulcer Due to Type 2 Diabetes Mellitus+4 more
Applied Biologics, LLC60 enrolled1 locationNCT07159282
Recruiting
Phase 4

Quantifying Hepatic Mitochondrial Fluxes in Humans

Non-Alcoholic Fatty Liver DiseaseType 2 DiabetesMitochondrial Metabolism Disorders
The University of Texas Health Science Center at San Antonio60 enrolled2 locationsNCT05305287
Recruiting
Phase 4

GLP1-RAs Effects on Inflammatory and Endothelial Biomarkers in T2DM

T2DM (Type 2 Diabetes Mellitus)
Federico II University80 enrolled2 locationsNCT07314684
Recruiting
Phase 4

Efficacy and Safety of the Met+SGLT-2i+GLP-1RA in Patients With Type 2 Diabetes With Poor Glycemic Control

T2DM (Type 2 Diabetes Mellitus)
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.430 enrolled1 locationNCT07244003
Recruiting
Phase 4

A Phase IV Clinical Trial to Compare the Efficacy and Safety of Metformin+Sodium-Glucose Cotransporter 2 Inhibitor(SGLT2-i)+Thiazolidinedione (TZD) in Patients With Type 2 Diabetes

Type 2 Diabetes
Boryung Pharmaceutical Co., Ltd204 enrolled1 locationNCT06972732
Recruiting
Phase 4

Efficacy and Safety of Henagliflozin Proline and Metformin Hydrochloride Extended-release Tablets (Ⅰ) Versus Metformin Tablets in Patients With New-onset Type 2 Diabetes: a Multicenter, Randomized Controlled Study

New-onset Type 2 Diabetes
Zhejiang Provincial People's Hospital268 enrolled1 locationNCT06888050
Recruiting
Phase 4

Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants

Type 2 Diabetes Mellitus in ObeseHeart Failure With Preserved Ejection Fraction
The University of Texas Health Science Center at San Antonio78 enrolled1 locationNCT05838287