Phase 1 Type 2 Diabetes Clinical Trials
49 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 49 trials
Recruiting
Phase 1
THC Effects on Glucose in Type 2 Diabetes
Type 2 Diabetes
University of California, San Diego30 enrolled1 locationNCT05322213
Recruiting
Phase 1Phase 2
A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM
Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled22 locationsNCT06845202
Recruiting
Phase 1
Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D
Overweight or Obese AdultsOverweight or Obese, Type 2 Diabetes
Alveus Therapeutics, Inc.180 enrolled2 locationsNCT07399678
Recruiting
Phase 1
A Study to Evaluate the Effect of Maridebart Cafraglutide on Insulin Sensitivity and β-cell Function in Participants With Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus
Amgen57 enrolled1 locationNCT07160257
Recruiting
Phase 1
A Study of LY4086940 in Healthy Participants and Participants With Overweight or Obesity, With or Without Type 2 Diabetes
ObesityHealthyOverweight+1 more
Eli Lilly and Company216 enrolled5 locationsNCT06945419
Recruiting
Phase 1
SGLT2i, Pioglitazone, and Ketone Production in T2D
Type 2 Diabetes
The University of Texas Health Science Center at San Antonio64 enrolled1 locationNCT07053319
Recruiting
Phase 1
FES Cycling With BFR in the Spinal Cord Injury Population
Spinal Cord InjuryMetabolic Diseases, Type 2 Diabetes, Cardiovascular DiseaseCardio Vascular Disease
Dr. B. Catharine. Craven6 enrolled1 locationNCT07588503
Recruiting
Phase 1
A Phase 1, Multiple Ascending Dose Study to Evaluate HMS1005 in Participants With Type 2 Diabetes
Type 2 Diabetes
Hua Medicine Limited40 enrolled1 locationNCT07568678
Recruiting
Phase 1
A Clinical Study to Evaluate the Pharmacokinetic and Pharmacodynamics Properties of of SHR-3167 in Subjects With Type 2 Diabetes
Type 2 Diabetes
Jiangsu HengRui Medicine Co., Ltd.55 enrolled1 locationNCT07032688
Recruiting
Phase 1
Phase I Study to Evaluate the Pharmacokinetics and Safety After Co-administration of L03RD1 and L03RD2 or Administration of L03TD1 in Healthy Volunteers
Type 2 Diabetes Mellitus (T2DM)
Celltrion48 enrolled1 locationNCT07533539
Recruiting
Phase 1
A Food-Effect Study of CX11 in Healthy Participants
Obesity, OverweightType 2 Diabetes
Vincentage Pharma Co., Ltd32 enrolled1 locationNCT07349381
Recruiting
Phase 1
A Study of REGEND003 on Patients With Type 2 Diabetes Mellitus (T2DM) and Chronic Kidney Disease (CKD)
Type 2 Diabetes Mellitus (T2DM) and Chronic Kidney Disease (CKD)
Regend Therapeutics15 enrolled1 locationNCT07275788
Recruiting
Phase 1
A Study to Evaluate the Effect of RO7204239 on Insulin Sensitivity and Muscle Composition in Participants With Type 2 Diabetes Mellitus (T2DM) and Overweight or Obesity
ObesityOverweightType 2 Diabetes Mellitus
Hoffmann-La Roche30 enrolled1 locationNCT07137585
Recruiting
Phase 1
A Study of PATAS Trifluoroacetate Using Single Ascending Doses in Healthy Volunteers
Type 2 Diabetes
AdipoPharma LLC56 enrolled2 locationsNCT07223333
Recruiting
Phase 1
A Study to Evaluate the Effect of AZD6793 on the Pharmacokinetics and Pharmacodynamics of Metformin in Participants With Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus
AstraZeneca28 enrolled1 locationNCT07433062
Recruiting
Phase 1
A Study to Evaluate Pharmacokinetics of LY3209590 in Pediatric Participants With Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus
Eli Lilly and Company22 enrolled10 locationsNCT06362265
Recruiting
Phase 1Phase 2
Triple Hypoglycemic Regimens In Patients With Newly Diagnosed Type 2 Diabetes Mellitus
Type 2 Diabetes
Second Affiliated Hospital of Guangzhou Medical University240 enrolled1 locationNCT07374328
Recruiting
Phase 1
Study to Assess Safety, Tolerability, PK, and PD of Multiple Doses of ZE63-0302 Administrated Orally in T2DM Patients.
Type 2 Diabetes
Eilean Therapeutics60 enrolled5 locationsNCT07234864
Recruiting
Phase 1
A Study to Evaluate the Effect of Fasting Duration and Dulaglutide (LY2189265) Withholding on Gastric Retention in Participants With Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus (T2DM)
Eli Lilly and Company20 enrolled1 locationNCT07313813
Recruiting
Phase 1
Phase 1/1b Study of TLC-6740 in Healthy Subjects and Subjects With Obesity, With or Without Diabetes
ObesityType 2 DiabetesHealthy Subjects
OrsoBio, Inc564 enrolled4 locationsNCT05822544