Upper Extremity Clinical Trials

46 recruitingLast updated: June 18, 2026

There are 46 actively recruiting upper extremity clinical trials across 14 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 4. Top locations include Cleveland, Ohio, United States, Shanghai, Shanghai Municipality, China, New York, New York, United States. Updated daily from ClinicalTrials.gov.


Upper Extremity Trials at a Glance

46 actively recruiting trials for upper extremity are listed on ClinicalTrialsFinder across 6 cities in 14 countries. The largest study group is Not Applicable with 31 trials, with the heaviest enrollment activity in Cleveland, Shanghai, and New York. Lead sponsors running upper extremity studies include Istinye University, Abant Izzet Baysal University, and University of Alabama at Birmingham.

Browse upper extremity trials by phase

Treatments under study

About Upper Extremity Clinical Trials

Looking for clinical trials for Upper Extremity? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Upper Extremity trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Upper Extremity clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 46 trials

Recruiting
Phase 1

Coordinated Reset Deep Brain Stimulation for Essential Tremor

Essential TremorUpper Extremity Essential Tremor
University of Minnesota23 enrolled1 locationNCT05897775
Recruiting

Assessment of Upper Extremity Proprioception in Patients With Cervical Radiculopathy

Cervical radiculopathyUpper ExtremityCervical Disc Herniation+3 more
Marmara University58 enrolled1 locationNCT07319156
Recruiting
Not Applicable

Rhythmic Initiation vs Isometric Training for Arm Recovery After Stroke

StrokeUpper Extremity Paresis
University of Faisalabad40 enrolled1 locationNCT07598435
Recruiting

Nerve Transfer Surgery to Restore Upper-limb Function After Cervical Spinal Cord Injury

Spinal Cord InjuryUpper Extremity ParesisSCI - Spinal Cord Injury+5 more
University of British Columbia40 enrolled4 locationsNCT05638191
Recruiting
Not Applicable

Virtual Reality Based Mirror Therapy

StrokeUpper Extremity ParesisUpper Extremity Paralysis
Abant Izzet Baysal University56 enrolled1 locationNCT06152328
Recruiting

Vivistim Registry for Paired VNS Therapy (GRASP)

Upper Extremity Problem
MicroTransponder Inc.1,000 enrolled15 locationsNCT05301140
Recruiting
Not Applicable

Constraint-Induced Movement Therapy Plus Sensory Components After Stroke

StrokeUpper Extremity ParesisCVA (Cerebrovascular Accident)
University of Alabama at Birmingham15 enrolled1 locationNCT05515237
Recruiting
Not Applicable

Web-based Mind-body Program to Improve Resilience Among Risky Substance Users With Persistent Upper Extremity Pain

Orthopedic DisorderNontraumatic InjuryUpper Extremity Pain+1 more
Jafar Bakhshaie50 enrolled1 locationNCT06991205
Recruiting
Not Applicable

Comparison of the Effects of Mirror Therapy,rTMS and Robotic-assisted Hand Therapy in Stroke Patients

Quality of LifeStrokeNeurologic Disorder+2 more
Afyonkarahisar Health Sciences University120 enrolled1 locationNCT06750692
Recruiting
Not Applicable

Wearable Focal Vibration Therapy on Upper Extremity Function of People With Multiple Sclerosis: A Pilot Study

Multiple Sclerosis (MS) - Relapsing-remittingUpper Extremity Dysfunction
University of Florida15 enrolled2 locationsNCT07376772
Recruiting
Not Applicable

Peripheral Interfaces in Amputees for Sensorimotor Integration

Upper Extremity Amputee
VA Office of Research and Development15 enrolled2 locationsNCT04430218
Recruiting
Not Applicable

Mirror vs Virtual Reality Therapy for Upper Extremity Function in Hemiplegic Patients

StrokeUpper Extremity DysfunctionHemiplegia
Istinye University42 enrolled1 locationNCT07018336
Recruiting
Not Applicable

Constraint-Induced Movement Therapy for Adults Post-Stroke With Mild Upper Extremity Impairment

StrokeUpper Extremity ParesisCVA (Cerebrovascular Accident)
University of Alabama at Birmingham12 enrolled1 locationNCT05492513
Recruiting

Upper Extremity Sensation and Function in Children With Cerebral Palsy

Sensation DisordersCerebral PalsyUpper Extremity Dysfunction
Abant Izzet Baysal University24 enrolled1 locationNCT07352735
Recruiting
Not Applicable

Pilot/Pivotal Study of DBS+Rehab After Stroke

StrokeUpper Extremity Paresis
Enspire DBS Therapy, Inc.202 enrolled10 locationsNCT05701280
Recruiting
Not Applicable

Effects of Combined vs. Sequential Attentional Focus Instructions on Upper Extremity Function in Subacute Stroke

StrokeUpper Extremity DysfunctionCue, Threat
Bahçeşehir University36 enrolled1 locationNCT07289308
Recruiting
Not Applicable

ICF-Based Effects of PNF and Kinesio Taping on Hand Function in Hemiplegic Stroke

Upper ExtremityHemiplegiaProprioceptive Neuromuscular Facilitation+3 more
Istinye University54 enrolled2 locationsNCT07014696
Recruiting
Phase 2

A Randomized Comparison Between 0.67 mcg/kg, 1 mcg/kg, and 1.33 mcg/kg of Perineural Dexmedetomidine for Ultrasound-Guided Infraclavicular Block

AnalgesiaPain, AcuteNerve Block+1 more
McGill University Health Centre/Research Institute of the McGill University Health Centre69 enrolled1 locationNCT07249827
Recruiting
Not Applicable

Combined Upper Extremity Resistance and Aerobic Exercise Training in Patients With Breast Cancer

Breast CancerAerobic ExerciseUpper Extremity+1 more
Hacettepe University40 enrolled1 locationNCT07070791
Recruiting
Not Applicable

Low Intensity Focused Ultrasound Stimulation in Stroke Patients - Parameter Optimization

StrokeArm Weakness as a Consequence of StrokeUpper Extremity Hemiparesis+2 more
Duke University24 enrolled1 locationNCT07220005