Weaning Clinical Trials

4 recruiting

Weaning Trials at a Glance

36 actively recruiting trials for weaning are listed on ClinicalTrialsFinder across 6 cities in 17 countries. The largest study group is Not Applicable with 13 trials, with the heaviest enrollment activity in Lyon, Istanbul, and Bordeaux. Lead sponsors running weaning studies include Assistance Publique - Hôpitaux de Paris, Cairo University, and Centre Hospitalier Régional d'Orléans.

Browse weaning trials by phase

Treatments under study

About Weaning Clinical Trials

Looking for clinical trials for Weaning? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Weaning trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Weaning clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 36 trials

Recruiting

Multidimensional Correlation Analysis of Heart Rate Variability and Weaning Assessment Parameters in Critically Mechanically Ventilated Patients

Weaning Invasive Mechanical Ventilation
Fu Jen Catholic University Hospital100 enrolled1 locationNCT07455214
Recruiting

Use of a Physiotherapy Assessment to Predict Extubation Failure in Mechanically Ventilated Patients: the EPIC Assessment

Mechanical VentilationMechanical Ventilator Weaning
Assistance Publique - Hôpitaux de Paris330 enrolled1 locationNCT06450678
Recruiting
Not Applicable

A Randomized Clinical Trial for Predictors of Successful Extubation of Pediatric Patients With or Without High Velocity Nasal Insufflation

High Velocity Nasal InsufflationSimple OxygenWeaning Criteria
Cairo University100 enrolled1 locationNCT07383051
Recruiting
Not Applicable

Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU

Weaning Failure
KU Leuven90 enrolled1 locationNCT04658498
Recruiting
Not Applicable

Speckle Tracking Echocardiography for the Prediction of Weaning Failure

Weaning Failure of Mechanical Ventilation
Assistance Publique Hopitaux De Marseille110 enrolled1 locationNCT03657524
Recruiting

Weaning Ventilator Using Heart, Lung And Diaphragm Ultrasound

UltrasoundVentilator Weaning
Hanoi Medical University190 enrolled1 locationNCT06321848
Recruiting

A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score

Respiratory FailureRespiration, ArtificialVentilator Weaning+1 more
Medipol University470 enrolled7 locationsNCT07098611
Recruiting
Not Applicable

Instrumental Respiratory Physiotherapy in Difficult-to-wean ICU Patients

Ventilator Weaning
Hospices Civils de Lyon50 enrolled3 locationsNCT06499389
Recruiting
Not Applicable

Evaluation of heepSync, a Novel Algorithm for Transcutaneous Electrical Stimulation of Respiratory Muscles in Mechanically Ventilated Patients.

Weaning FailureVentilator-induced Diaphragm DysfunctionVIDD
Tesai Care SL20 enrolled3 locationsNCT07363902
Recruiting
Phase 4

Shorter Weaning From Invasive Ventilation With Levosimendan

Mechanical VentilationWeaning Failure
Radboud University Medical Center250 enrolled8 locationsNCT07105202
Recruiting
Not Applicable

Endotracheal Suctionning During Positive Pressure Extubation in ICU

Weaning Invasive Mechanical VentilationExtubationOxygen Saturation Measurement+2 more
Centre Hospitalier Régional d'Orléans120 enrolled1 locationNCT07130123
Recruiting

Surface Electrical Myography, Oxygen Consumption, Effort, and Weaning in the Mechanically Ventilated Patient in the Intensive Care Unit

Mechanical VentilationCritical IllnessIntensive Care Units (ICUs)+3 more
Leiden University Medical Center60 enrolled1 locationNCT07109570
Recruiting
Not Applicable

Optimal Timing for Spontaneous Breathing Trials

WeaningRespiration, Artificial
Rush University Medical Center348 enrolled1 locationNCT06561295
Recruiting
Not Applicable

Brain-injured Patients Extubation Readiness Study

Mechanical Ventilator Weaning
University Hospital, Clermont-Ferrand660 enrolled21 locationsNCT04080440
Recruiting

Evaluation of Left Ventricular Function to Predict Weaning Success in the Intensive Care Unit

Weaning Failure of Mechanical Ventilation
Kanuni Sultan Suleyman Training and Research Hospital50 enrolled1 locationNCT07075926
Recruiting

Evaluation of Right Ventricular Function to Predict Weaning Success in the Intensive Care Unit

Weaning Failure of Mechanical Ventilation
Kanuni Sultan Suleyman Training and Research Hospital60 enrolled1 locationNCT07073976
Recruiting
Not Applicable

High Flow Nasal Cannula Versus High Velocity Nasal Insufflation for Weaning

Weaning From Mechanical Ventilation
Assiut University90 enrolled1 locationNCT07133698
Recruiting

PPI in Weaning Prediction

ICUPerfusion IndexWeaning of Mechanical Ventilation
Gaziosmanpasa Research and Education Hospital100 enrolled1 locationNCT07120672
Recruiting

Effects of Nasal Airflow on Sleep in Tracheotomized Patients

Patients With Prolonged Weaning
Assistance Publique - Hôpitaux de Paris24 enrolled1 locationNCT06547463
Recruiting

Doxapram Administration on Diaphragmatic Excursion in Mechanically Ventilated Patients With Chronic Obstructive Pulmonary Disease Undergoing Spontaneous Breathing Trial

COPDMechanical VentilationWeaning From Mechanical Ventilation
Cairo University35 enrolled1 locationNCT07022704