Clinical Trials in Newcastle upon Tyne, Tyne and Wear
23 recruiting
Showing 1–20 of 22 trials
Recruiting
Phase 3
A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy
Primary IgA Nephropathy
Novartis Pharmaceuticals540 enrolled161 locationsNCT04557462
Recruiting
A Study of Lanadelumab in Children With Hereditary Angioedema (HAE) in Multiple Countries
Hereditary Angioedema (HAE)
Takeda40 enrolled24 locationsNCT07251933
Recruiting
Phase 1
First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)
Advanced Metastatic Castration-resistant Prostate CancerProstate Specific Membrane Antigen (PSMA) Expression
Bayer198 enrolled35 locationsNCT06217822
Recruiting
Phase 3
Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS)
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals50 enrolled31 locationsNCT05935215
Recruiting
Phase 3
Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.
C3G
Novartis Pharmaceuticals98 enrolled87 locationsNCT04817618
Recruiting
Phase 3
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
Left Ventricular Systolic DysfunctionHeart Failure (Pediatric)
Bayer111 enrolled133 locationsNCT07188805
Recruiting
Phase 2
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
Atrial Fibrillation
Novartis Pharmaceuticals165 enrolled38 locationsNCT07217067
Recruiting
Phase 3
ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)
GliomaH3 K27M
Jazz Pharmaceuticals510 enrolled162 locationsNCT05580562
Recruiting
Phase 3
Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN
C3 GlomerulopathyImmune-complex-membranoproliferative Glomerulonephritis
Novartis Pharmaceuticals225 enrolled50 locationsNCT03955445
Recruiting
Phase 3
A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults
Influenza
ModernaTX, Inc.4,000 enrolled36 locationsNCT07496450
Recruiting
Phase 3
Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD)
Autosomal Dominant Polycystic Kidney Disease
The University of Queensland1,174 enrolled49 locationsNCT04939935
Recruiting
PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
Parkinson Disease
Michael J. Fox Foundation for Parkinson's Research4,500 enrolled50 locationsNCT04477785
Recruiting
Phase 1Phase 2
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Breast CancerTriple-Negative Breast CancerColorectal, Cancer+26 more
PMV Pharmaceuticals, Inc300 enrolled76 locationsNCT04585750
Recruiting
A Study to Learn How Nusinersen (Spinraza) Affects Participants With Spinal Muscular Atrophy (SMA) Who Took it Before or During Pregnancy And About The Health of Their Babies
Muscular Atrophy, Spinal
Biogen20 enrolled14 locationsNCT05789758
Recruiting
Clinical Validity of the DANU Sports System for Gait and Balance Assessment in Parkinson's Disease
Parkinson Disease (PD)Healthy (Controls)
Northumbria University60 enrolled2 locationsNCT07281794
Recruiting
International Registry Study of Neutral Lipid Storage Disease (NLSD) / Triglyceride Deposit Cardiomyovasculopathy (TGCV) and Related Diseases
Neutral Lipid Storage Disease
Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan120 enrolled15 locationsNCT02918032
Recruiting
Not Applicable
Patient Engagement Investigation of NMS Assist
Parkinson Disease
Newcastle University30 enrolled1 locationNCT07038486
Recruiting
Phase 2
Early Longitudinal Imaging in the Parkinson's Progressive Marker Initiative (PPMI) Using (18F)AV-133 (PPMI AV-133 Prodromal Imaging)
Prodromal Parkinsons Disease
Michael J. Fox Foundation for Parkinson's Research100 enrolled8 locationsNCT07265596
Recruiting
Not Applicable
GB-PRIME: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices
QuadriplegiaSpinal Cord InjuryMotor Neuron Disease+6 more
Neuralink Corp7 enrolled2 locationsNCT07127172
Recruiting
Phase 1Phase 2
First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.
Solid Tumor
Corbus Pharmaceuticals Inc.156 enrolled26 locationsNCT06603844