Early Phase 1 AIN Clinical Trials
69 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 69 trials
Recruiting
Early Phase 1
Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)
Brain CancerGliomaHigh Grade Glioma+4 more
Eben Rosenthal38 enrolled1 locationNCT07210632
Recruiting
Early Phase 1
Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms
Breast CancerAromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)Joint Pain
Philip Chang30 enrolled2 locationsNCT06123286
Recruiting
Early Phase 1
Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?
Migraine
Texas Tech University Health Sciences Center, El Paso84 enrolled1 locationNCT06016465
Recruiting
Early Phase 1
Repeated CBD Administration and Cannabis Outcomes
CannabisAbuse LiabilityExperimental Pain in Healthy Human Participants
Hannah Harris23 enrolled1 locationNCT07434895
Recruiting
Early Phase 1
The Potential of Oxytocin to Reduce Opioid Abuse Liability and Pain Among Older Adults
Pain
University of Florida45 enrolled1 locationNCT05761860
Recruiting
Early Phase 1
A Pilot Trial of Disposable Nitrous Oxide Canisters in Providing Pain Control During Burn Dressing Changes
Pain, AcuteBurns
University of Manitoba30 enrolled1 locationNCT03695887
Recruiting
Early Phase 1
Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery
PainBrain InjuryBrain Tumors+3 more
University of Virginia40 enrolled1 locationNCT06810336
Recruiting
Early Phase 1
The Role of NaV1.8 in Human Pain Models
PainHealthy Volunteer StudyAcute Pain
Medical University of Vienna66 enrolled1 locationNCT07511400
Recruiting
Early Phase 1
Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG
GliomaGlioma, MalignantLow-grade Glioma+2 more
Children's Hospital of Philadelphia30 enrolled1 locationNCT05555550
Recruiting
Early Phase 1
Nebulized Dexmedetomidine or Lidocaine for Treatment of Post Dural Puncture Headache in Parturients Undergoing Elective Cesarean Section Under Spinal Anesthesia
Pain Score (VAS)
Minia University114 enrolled1 locationNCT06607861
Recruiting
Early Phase 1
Efficacy of a Topical Palmitated Formulation of Capsaicin (Capsadyn®) In the Treatment of Diabetic Neuropathic Foot Pain
Diabetic FootDiabetic Peripheral NeuropathyDiabetic Neuropathies, Painful
Carilion Clinic80 enrolled1 locationNCT07260656
Recruiting
Early Phase 1
Safety and Efficacy of Mesenchymal Stem Cells Associated With Chronic Pancreatitis Pain
Chronic PainChronic Pancreatitis
Medical University of South Carolina48 enrolled1 locationNCT06205342
Recruiting
Early Phase 1
Study of Letrozole in Recurrent Gliomas
Brain Tumor
University of Cincinnati39 enrolled1 locationNCT03122197
Recruiting
Early Phase 1
Ketamine and Propofol NeuroImaging
PainAnesthesia
Keith M Vogt60 enrolled1 locationNCT07294092
Recruiting
Early Phase 1
Nitrous Oxide Neuroimaging
PainAnesthesiaAmnesia
Keith M Vogt60 enrolled1 locationNCT06702631
Recruiting
Early Phase 1
Cannabidiol in Opioid Use Disorder and Chronic Pain
Chronic PainOpioid-use Disorder
Yale University34 enrolled1 locationNCT04587791
Recruiting
Early Phase 1
A Study of Niacin Regulation
Excessive Weight Gain
Mayo Clinic32 enrolled1 locationNCT06175403
Recruiting
Early Phase 1
Stimulating After Recovery From Traumatic Brain Injury
TBI (Traumatic Brain Injury)
University of Minnesota30 enrolled1 locationNCT05327829
Recruiting
Early Phase 1
Remimazolam NeuroImaging
PainAnesthesiaRemimazolam
Keith M Vogt60 enrolled1 locationNCT07290205
Recruiting
Early Phase 1
Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion
DeliriumPain, BackSpinal Fusion+1 more
University of Iowa50 enrolled1 locationNCT05461092