Phase 1 Alcohol Use Disorder Clinical Trials
17 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–17 of 17 trials
Recruiting
Phase 1
Environment and Alcohol: A Pilot Study
Alcohol Use Disorder
National Institute on Drug Abuse (NIDA)44 enrolled1 locationNCT06860607
Recruiting
Phase 1
Spironolactone in Alcohol Use Disorder (SAUD)
Alcohol Use Disorder
National Institute on Drug Abuse (NIDA)20 enrolled1 locationNCT05807139
Recruiting
Phase 1
The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)
Alcohol Use Disorder (AUD)Alcohol-Related DisordersAlcohol Use
Yale University63 enrolled1 locationNCT06070649
Recruiting
Phase 1Phase 2
Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms
Healthy VolunteersAlcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)180 enrolled1 locationNCT06484075
Recruiting
Phase 1
PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder
Alcohol Use Disorder
National Institute of Mental Health (NIMH)30 enrolled1 locationNCT06795581
Recruiting
Phase 1
Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B)
Alcohol Use Disorder
National Institute of Mental Health (NIMH)30 enrolled1 locationNCT07027839
Recruiting
Phase 1
Study of NTX-2001 on Alcohol Consumption in Alcohol Use Disorder
Alcohol Use Disorder
Newleos Therapeutics, Inc.50 enrolled1 locationNCT07520292
Recruiting
Phase 1Phase 2
A First in Human Study of CMND-100 in Healthy and Alcohol Use Disorder (AUD) Subjects
Alcohol Use Disorder
Clearmind Medicine Inc.84 enrolled4 locationsNCT05913752
Recruiting
Phase 1
Diclofenac Dose Response Study
Alcohol Use Disorder (AUD)Alcohol-Related Disorders
University of Maryland, Baltimore24 enrolled1 locationNCT06636227
Recruiting
Phase 1
Sex Differences in the Response to Abstinence From Alcohol.
Alcohol Use Disorder
Indiana University160 enrolled1 locationNCT03827460
Recruiting
Phase 1
Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study
Post Traumatic Stress Disorder (PTSD)Alcohol Use Disorder (AUD)
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance10 enrolled1 locationNCT06335407
Recruiting
Phase 1
The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration
Age-Related Macular DegenerationAlcohol Use DisorderRetinitis Pigmentosa+2 more
University of Rochester15 enrolled1 locationNCT06319872
Recruiting
Phase 1Phase 2
Intranasal Insulin for Treatment of Alcohol Use Disorder
Alcohol Use Disorder
Brown University40 enrolled1 locationNCT05988632
Recruiting
Phase 1
Influence of Mavoglurant on Alcohol Craving and Drinking in Heavy Drinkers
Heavy DrinkerAlcohol ConsumptionAlcohol Use Disorder (AUD)
Yale University63 enrolled2 locationsNCT06136195
Recruiting
Phase 1
PT150 Drug for Use in Alcohol Use Disorder
Alcohol Use Disorder
Pop Test Oncology LLC34 enrolled1 locationNCT06712602
Recruiting
Phase 1Phase 2
Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease
CirrhosisAlcohol Use DisorderLiver Disease; Alcohol-Related
Virginia Commonwealth University80 enrolled2 locationsNCT05548452
Recruiting
Phase 1
An open label study to evaluate the safety, tolerability, and subjective effects of two dimethyltryptamine (DMT) and harmala alkaloid containing formulations in healthy volunteers
DepressionAlcohol Use DisorderTrauma
St Vincent's Hospital, Melbourne8 enrolled1 locationACTRN12622001315707