Phase 2 Alcohol Use Disorder Clinical Trials

53 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 53 trials

Recruiting
Phase 2

Human Laboratory Study of Apremilast for Alcohol Use Disorder

Alcohol Use DisorderAlcohol Misuse
National Institute on Alcohol Abuse and Alcoholism (NIAAA)100 enrolled3 locationsNCT07325266
Recruiting
Phase 2

Semaglutide Therapy for Alcohol Reduction (STAR)

Alcohol Use DisorderAddiction
National Institute on Drug Abuse (NIDA)67 enrolled1 locationNCT06015893
Recruiting
Phase 2

Motivation for IV Alcohol Self-Administration in Humans

Alcohol Use Disorder
University of California, Los Angeles210 enrolled1 locationNCT06494891
Recruiting
Phase 2

Brexpiprazole in Alcohol Use Disorder

Alcohol Use Disorder
University of Colorado, Denver250 enrolled1 locationNCT04066192
Recruiting
Phase 1Phase 2

Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms

Healthy VolunteersAlcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)180 enrolled1 locationNCT06484075
Recruiting
Phase 2

LSD Treatment for Persons With Alcohol Use Disorder

Alcohol Use Disorder (AUD)
Felix Mueller128 enrolled2 locationsNCT05474989
Recruiting
Phase 2

Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD

Alcohol Use DisorderPosttraumatic Stress Disorder
Texas A&M University200 enrolled2 locationsNCT05959434
Recruiting
Phase 2

Tirzepatide in MetALD

Alcohol Use DisorderMetabolic Alcohol-associated Liver Disease
National Institute on Alcohol Abuse and Alcoholism (NIAAA)120 enrolled1 locationNCT07046819
Recruiting
Phase 2

Cannabidiol and Alcohol Use Disorder Phenotypes

Alcohol Use Disorder
University of Colorado, Denver150 enrolled1 locationNCT07279558
Recruiting
Phase 1Phase 2

A First in Human Study of CMND-100 in Healthy and Alcohol Use Disorder (AUD) Subjects

Alcohol Use Disorder
Clearmind Medicine Inc.84 enrolled4 locationsNCT05913752
Recruiting
Phase 2

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2

Alcohol Use Disorder
Yale University30 enrolled1 locationNCT06006143
Recruiting
Phase 2

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide

HIVAlcohol Use Disorder (AUD)
Yale University30 enrolled1 locationNCT07040592
Recruiting
Phase 2

Evaluating Cannabidiol as a Novel Anticraving Medication for Alcohol Use Disorder

Alcohol Use Disorder
Centre for Addiction and Mental Health36 enrolled1 locationNCT06512389
Recruiting
Phase 2

Alpha-1 Blockade for Alcohol Use Disorder (AUD)

Alcohol Use Disorder (AUD)
Brown University184 enrolled1 locationNCT04135846
Recruiting
Phase 2

Probenecid Administration for Alcohol Craving and Consumption

Alcohol ConsumptionAlcohol Use Disorder (AUD)Craving
Brown University120 enrolled1 locationNCT07118618
Not Yet Recruiting
Phase 2

PANDA: Psilocybin-assisted therapy for treatment of alcohol use disorder and comorbid depression

Major Depressive DisorderAlcohol Use Disorder
Eastern Health10 enrolled1 locationACTRN12626000316303
Recruiting
Phase 2

Effects of Tirzepatide on Alcohol Intake in Patients Diagnosed With Schizophrenia and Alcohol Use Disorder

AlcoholismSchizophrenia DisordersAlcohol Use Disorder+2 more
Anders Fink-Jensen, MD, DMSci108 enrolled2 locationsNCT06939088
Recruiting
Phase 2Phase 3

Ketone Ester Intervention in Alcohol Use Disorder

Alcohol DrinkingAlcohol Use Disorder
University of Pennsylvania20 enrolled1 locationNCT04616781
Recruiting
Phase 2

Pregnenolone for the Treatment of Alcohol Use Disorder

Alcohol Use Disorder
Yale University150 enrolled1 locationNCT05781009
Recruiting
Phase 2

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 1

Alcohol Use Disorder
Yale University30 enrolled1 locationNCT06004830