ALT Clinical Trials in Boston, Massachusetts

56 recruitingBoston, Massachusetts

Showing 120 of 56 trials

Recruiting
Phase 1Phase 2

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled85 locationsNCT06649110
Recruiting
Phase 1

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

Solid Tumors With HRAS Alterations
Kura Oncology, Inc.300 enrolled40 locationsNCT06026410
Recruiting
Early Phase 1

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

GlioblastomaGlioblastoma MultiformeHigh Grade Glioma+6 more
Nationwide Children's Hospital15 enrolled18 locationsNCT06333899
Recruiting

Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD

Mild Cognitive ImpairmentHealthy AgingSubjective Cognitive Concerns+1 more
Massachusetts General Hospital250 enrolled1 locationNCT05881239
Recruiting
Phase 1Phase 2

Study of RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities

RET-altered Non Small Cell Lung CancerRET-altered Solid Tumors
Taiho Pharmaceutical Co., Ltd.244 enrolled21 locationsNCT04683250
Recruiting
Phase 1Phase 2

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

Recurrent Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmRecurrent Lymphoma+7 more
Children's Oncology Group63 enrolled34 locationsNCT04870944
Recruiting
Not Applicable

TMS for Cognitive Decline in Aging and Preclinical AD

Cognitive DeclineHealthy AgingProdromal Alzheimer's Disease+1 more
Massachusetts General Hospital80 enrolled1 locationNCT06956300
Recruiting
Not Applicable

Pilot Study of a Brain Health Program in Senior Centers

Lifestyle (Sedentary Behavior and Physical Activity)Lifestyle Risk ReductionMemory Loss (Excluding Dementia)+2 more
Massachusetts General Hospital60 enrolled1 locationNCT07424443
Recruiting
Phase 1

AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

KRAS Altered Advanced or Metastatic Solid Tumors
Amgen434 enrolled27 locationsNCT07094113
Recruiting
Early Phase 1

The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response

Heat StrainHealthy Volunteer StudyKidney Dysfunction
Beth Israel Deaconess Medical Center28 enrolled2 locationsNCT06983730
Recruiting
Not Applicable

A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule

Lynch SyndromeHealthyInflammatory Bowel Diseases+1 more
Massachusetts General Hospital30 enrolled1 locationNCT07219537
Recruiting
Phase 1

Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

Solid TumorsMetastatic Hepatocellular CarcinomaAdvanced Solid Tumors+11 more
Tyra Biosciences, Inc100 enrolled16 locationsNCT06915753
Recruiting
Not Applicable

Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance

HealthyInflammatory Bowel DiseasesCrohn Disease
Massachusetts General Hospital10 enrolled1 locationNCT07033208
Recruiting
Phase 1Phase 2

A Study of an FGFR2/3 Inhibitor (CGT4859) in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors

CholangiocarcinomaAdvanced Solid TumorsIntrahepatic Cholangiocarcinoma (Icc)+9 more
Cogent Biosciences, Inc.110 enrolled15 locationsNCT06777316
Recruiting
Phase 2

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

Pancreatic CancerGastric CancerLung Cancer+15 more
Apollomics Inc.497 enrolled35 locationsNCT03175224
Recruiting

Clinical Validation of Samsung Smartwatch

Mental Health IssueMajor Depressive DisorderMood Disorders
Massachusetts General Hospital220 enrolled1 locationNCT05767593
Recruiting
Not Applicable

Deep Learning Using Chest X-Rays to Identify High Risk Patients for Lung Cancer Screening CT

Lung CancerDeep LearningHealth Screening+1 more
Massachusetts General Hospital1,500 enrolled1 locationNCT06910956
Recruiting
Phase 1

Exploratory Clinical Study to Assess Safety and Efficacy of Xenon Gas Inhalation to Control Neuroinflammation

Healthy Volunteer Study
General Biophysics LLC16 enrolled1 locationNCT06945614
Recruiting
Not Applicable

Mindfulness for Cognition in Early-stage Alzheimer's Disease

AgingMild Cognitive Impairment (MCI)Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease+3 more
VA Boston Healthcare System100 enrolled1 locationNCT06792877
Recruiting

Apple Women's Health Study

MenopauseInfertilityPolycystic Ovary Syndrome+5 more
Apple Inc.500,000 enrolled1 locationNCT04196595