Phase 2 Anxiety Clinical Trials

67 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 67 trials

Recruiting
Phase 2

Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety

Anxiety DisordersPsychiatric Disorders
National Institute of Mental Health (NIMH)150 enrolled1 locationNCT06595953
Recruiting
Phase 2

A Phase 2a Efficacy, Safety, Tolerability, and PK Study of SYT-510 in Participants With Generalized Anxiety Disorder

Generalized Anxiety Disorder
Synendos Therapeutics AG24 enrolled1 locationNCT07478744
Recruiting
Phase 2

Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder

Generalized Anxiety Disorder (GAD)
AbbVie315 enrolled52 locationsNCT06846320
Recruiting
Phase 2

Cannabidiol and Older Adult Cannabis Users

PainDepressionSleep+1 more
University of Colorado, Boulder385 enrolled1 locationNCT06290063
Recruiting
Phase 2

Intranasal Dexmedetomidine for Acute Anxiety State in Adults

Acute Anxiety States
Tongji University150 enrolled1 locationNCT07550881
Recruiting
Phase 2

Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders

Major Depressive DisorderAnxiety Disorders
National Institute of Mental Health (NIMH)3,500 enrolled2 locationsNCT00018057
Recruiting
Phase 2

Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies

Hematopoietic and Lymphatic System NeoplasmMetastatic Malignant Solid NeoplasmDepression+1 more
University of Washington18 enrolled1 locationNCT07336238
Recruiting
Phase 2

Study of Dextromethorphan in OCD and Related Disorders

Obsessive-Compulsive DisorderSomatic Symptom DisorderIllness Anxiety Disorder+1 more
Stanford University60 enrolled1 locationNCT04899687
Recruiting
Phase 2

Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation

Anxiety DisorderDepressive Disorder, Major
Mclean Hospital112 enrolled1 locationNCT05232032
Recruiting
Phase 2

RE104 Safety and Efficacy Study in Generalized Anxiety Disorder

Generalized Anxiety Disorder
Reunion Neuroscience Inc64 enrolled12 locationsNCT07489651
Recruiting
Phase 2

Modulating Exercise Dosage to Improve Concussion Recovery

TreatmentDepression, AnxietyAerobic Exercise+2 more
University of Colorado, Denver216 enrolled3 locationsNCT05434130
Recruiting
Phase 1Phase 2

Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease

Quality of LifeDepression, AnxietyStress Reaction+1 more
Children's Hospital Los Angeles66 enrolled1 locationNCT05685368
Recruiting
Phase 2

Evaluating Buspirone to Treat Opioid Withdrawal

AnxietyOpioid-use DisorderOpioid Withdrawal+1 more
University of Maryland, Baltimore100 enrolled1 locationNCT05511909
Recruiting
Phase 2

Lysergic Acid Diethylamide (LSD) in Palliative Care

PainQuality of LifePsychological Distress+7 more
University Hospital, Basel, Switzerland60 enrolled4 locationsNCT05883540
Recruiting
Phase 2

Sleep and Stress Study

StressAnxietySleep Disorder (Disorder)
RDC Clinical Pty Ltd240 enrolled1 locationNCT07315516
Recruiting
Phase 2

A New Intervention to Improve Function in Veterans With Anxiety and Depression

Anxiety and Depression
VA Office of Research and Development84 enrolled1 locationNCT06188923
Recruiting
Phase 2

TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors

CancerDepressionAnxiety
M.D. Anderson Cancer Center20 enrolled1 locationNCT06801041
Recruiting
Phase 2

Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy

Advanced CancerDepression, AnxietyPsilocybin-Assisted Psychotherapy
M.D. Anderson Cancer Center30 enrolled1 locationNCT06200155
Recruiting
Phase 2

Investigating a Marijuana-based Compound as a Treatment for Anxiety in Autistic Adults

AnxietyAutism Spectrum Disorder
Southwest Autism Research & Resource Center108 enrolled1 locationNCT06526208
Recruiting
Phase 2

SSRI Antidepressant Fluoxetine Improving Immunotherapy Efficacy in Advanced Hepatobiliary Malignancy Patients With Depression and Anxiety

Anxiety DisordersDepression DisordersHepatobiliary Malignancy+1 more
First Affiliated Hospital of Wenzhou Medical University240 enrolled1 locationNCT07174947