Phase 4 arthroplasty Clinical Trials
24 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 24 trials
Recruiting
Phase 4
Medrol Dosepak for Outpatient Total Knee Arthroplasty
Total Knee Arthroplasty
Rush University Medical Center420 enrolled1 locationNCT05097976
Recruiting
Phase 4
Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter Reverses Tourniquet Associated Ischemic Hypertension
Tourniquet HypertensionIntraoperative HypertensionTotal Ankle Arthroplasty+1 more
Duke University40 enrolled1 locationNCT04454203
Recruiting
Phase 4
Addition of a Pectoserratus Block to Interscalene Block in Patients Undergoing Total Shoulder Replacement
Total Shoulder Arthroplasty
University of Minnesota110 enrolled1 locationNCT06143306
Recruiting
Phase 4
Intravenous Dexamethasone Administration in Patients Undergoing Total Shoulder Arthroplasty
Arthroplasty, Replacement, Shoulder
Christian Candrian74 enrolled1 locationNCT04507412
Recruiting
Phase 4
Nalbuphine Timing Effects on Hemodynamics and Analgesia in Elderly Patients
Postoperative Pain, AcuteHemodynamicsTotal Knee Arthroplasty (TKA)
Qianfoshan Hospital162 enrolled1 locationNCT07271849
Recruiting
Phase 4
Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty
Osteoarthritis, KneeTotal Knee ArthroplastyChronic Postsurgical Pain
Vanderbilt University Medical Center148 enrolled1 locationNCT06083480
Recruiting
Phase 4
A Prospective, Randomized Parallel Group Study of the Efficacy of Vancomycin Administered Through Intraarticular Injection Versus Intraosseous Injection Versus Intravenous Infusion in Patients Undergoing Total Knee Arthroplasty
Total Knee Arthroplasty
University of California, San Diego30 enrolled1 locationNCT07282782
Not Yet Recruiting
Phase 4
Extended Postoperative Oral Tranexamic Acid In Total Hip and Knee Arthroplasty: A Randomised Controlled Study
OsteoarthritisTotal Hip ArthroplastyTotal Knee Arthroplasty
North Sydney Orthopaedic Research Group200 enrolled1 locationACTRN12625000926437
Recruiting
Phase 4
Effects on Postoperative Pain of Liposomal Bupivacaine in Interscalene Blocks for Total Shoulder Arthroplasty Patients
Total Shoulder ArthroplastyReverse Total Shoulder Arthroplasty
Johnny K. Lee120 enrolled1 locationNCT05900427
Recruiting
Phase 4
The Perioperative Outcome of Epinephrine Infusion and Tranexamic Acid in Knee Arthroplasty Surgery
blood lossKnee Arthroplasty, TotalKnee Arthritis, Osteoarthritis+3 more
King Abdullah International Medical Research Center80 enrolled1 locationNCT07089251
Recruiting
Phase 4
Kinematic and Mechanical Alignment Randomized Trial
OsteoarthritisTotal Knee Arthroplasty
McMaster University260 enrolled1 locationNCT06787417
Recruiting
Phase 4
The Utility of Pericapsular Nerve Group (PENG) Block versus Intrathecal Morphine for Postoperative Analgesia in Anterior Approach Total Hip Arthroplasty: A Multicentre Triple Blinded Randomised Controlled Trial
Hip ArthroplastyPain Management
Tim Cheok70 enrolled1 locationACTRN12623001309673
Completed
Phase 4
Investigating the effect of tranexamic acid on recovery time in patients undergoing total knee replacements
Peri-operative bleeding with Total Knee ArthroplastyTotal Knee Arthroplasty
Wesley Medical Research80 enrolled2 locationsACTRN12621001327875
Not Yet Recruiting
Phase 4
Investigating the effectiveness of Prophylactic Hypotension Avoidance iN arThrOplasty using Midodrine (PHANTOM) pilot trial
Hip ArthroplastySurgeryHypotension+1 more
Royal Perth Hospital166 enrolled1 locationACTRN12621000943842
Recruiting
Phase 4
Optimising pain relief after knee joint replacement surgery at Counties Manukau Health; We compare two methods of local anaesthesia (numbing medicine) administration to reduce pain after knee replacement surgery.
Pain relief after Total Knee Arthroplasty
Counties Manukau Health, Middlemore Hospital Research Office72 enrolled1 locationACTRN12619000221156
Terminated
Phase 4
A clinical trial to determine if aspirin is as effective and safe as low molecular weight heparin in preventing lung and leg clots after total hip or knee replacement surgery
Venous Thromboembolic Events (VTE) after Total Hip Arthroplasty (THA) and Total Knee Arthroplasty (TKA)
University of New South Wales15,562 enrolled1 locationACTRN12618001879257
Not Yet Recruiting
Phase 4
Perioperative analgesia for elective total hip arthroplasty
Perioperative analgesia for elective total hip arthroplasty
Hospital Complex of Navarra (Complejo Hospitalario de Navarra)500 enrolled1 locationACTRN12618001474246
Recruiting
Phase 4
The efficacy of topical preparations in reducing the incidence of P. Acnes in total shoulder arthroplasty
Total Shoulder ArthroplastyShoulder Osteoarthritis
Orthopaedic Research Institute Queensland105 enrolled1 locationACTRN12618000261213
Recruiting
Phase 4
Postoperative analgesia for elective total knee arthroplasty
Postoperative analgesia for elective total knee arthroplasty
Hospital Complex of Navarra500 enrolled1 locationACTRN12616000912482
Completed
Phase 4
Intravenous tranexamic acid ("TXA") and its effect on operating conditions, blood loss, post-operative pain and complications in patients undergoing total shoulder replacement.
Blood loss in total shoulder arthroplasty
Dr Benjamin Cass150 enrolled3 locationsACTRN12616000723482