Brain Neoplasm Clinical Trials

44 recruitingLast updated: June 18, 2026

There are 44 actively recruiting brain neoplasm clinical trials across 21 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 3. Top locations include Los Angeles, California, United States, Boston, Massachusetts, United States, Houston, Texas, United States. Updated daily from ClinicalTrials.gov.


Brain Neoplasm Trials at a Glance

44 actively recruiting trials for brain neoplasm are listed on ClinicalTrialsFinder across 6 cities in 21 countries. The largest study group is Not Applicable with 15 trials, with the heaviest enrollment activity in Los Angeles, Boston, and Houston. Lead sponsors running brain neoplasm studies include Mayo Clinic, M.D. Anderson Cancer Center, and Jonsson Comprehensive Cancer Center.

Browse brain neoplasm trials by phase

Treatments under study

About Brain Neoplasm Clinical Trials

Looking for clinical trials for Brain Neoplasm? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Brain Neoplasm trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Brain Neoplasm clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 44 trials

Recruiting

Tumor Related Epilepsy

CancerEpilepsyBrain Neoplasm
National Institute of Neurological Disorders and Stroke (NINDS)100 enrolled1 locationNCT02639325
Recruiting
Phase 1

Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and Young Adult Patients With Resectable, Recurrent Primary Malignant Brain Tumors

Resectable Brain NeoplasmRecurrent Diffuse Hemispheric Glioma, H3 G34-MutantRecurrent Malignant Brain Neoplasm
University of Michigan Rogel Cancer Center11 enrolled1 locationNCT06914479
Recruiting
Phase 1

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

MelanomaNon-small Cell Lung CancerThyroid Cancer+10 more
Pfizer124 enrolled82 locationsNCT05538130
Recruiting
Not Applicable

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

Malignant Brain NeoplasmMalignant Solid NeoplasmProstate Carcinoma+2 more
Mayo Clinic147 enrolled1 locationNCT06788886
Recruiting
Phase 1Phase 2

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Breast NeoplasmsBreast DiseasesNeoplasms+5 more
Stemline Therapeutics, Inc.73 enrolled86 locationsNCT05386108
Recruiting
Not Applicable

The Effect of Education Brain Tumors

Primary Brain Neoplasms
Istanbul University - Cerrahpasa72 enrolled1 locationNCT07617168
Recruiting
Not Applicable

Intravital Microscopy in Human Solid Tumors

Malignant Brain NeoplasmMalignant Solid NeoplasmAnatomic Stage IV Breast Cancer AJCC v8+20 more
Mayo Clinic85 enrolled1 locationNCT03823144
Recruiting
Phase 1Phase 2

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

Brain TumorBrain CancerGlioblastoma+4 more
Northwell Health33 enrolled1 locationNCT02861898
Recruiting

Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors

Malignant Brain NeoplasmMalignant Solid NeoplasmMalignant Testicular Neoplasm+97 more
University of Southern California250 enrolled2 locationsNCT07259304
Recruiting
Not Applicable

Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors

Metastatic Malignant Neoplasm in the BrainBrain NeoplasmRecurrent Brain Neoplasm
M.D. Anderson Cancer Center75 enrolled1 locationNCT02754544
Recruiting
Phase 2

An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain Tumors

Malignant Brain Neoplasm
Mayo Clinic47 enrolled1 locationNCT06667726
Recruiting
Phase 2

Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA

Brain TumorBrain CancerGlioblastoma+6 more
Northwell Health37 enrolled1 locationNCT02800486
Recruiting
Not Applicable

Cancer Genetic Testing in Ethnic Populations

Breast CarcinomaHead and Neck CarcinomaMalignant Brain Neoplasm+8 more
Mayo Clinic1,800 enrolled2 locationsNCT04475640
Recruiting
Phase 3

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Brain TumorGlioblastomaGBM+1 more
Ivy Brain Tumor Center450 enrolled95 locationsNCT06388733
Recruiting
Not Applicable

Guided Meditation During Radiation Therapy for Brain Tumors

Brain Neoplasms
University of Utah30 enrolled1 locationNCT06165653
Recruiting

Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology

Central Nervous System NeoplasmMetastatic Malignant Neoplasm in the BrainPrimary Brain Neoplasm+1 more
M.D. Anderson Cancer Center200 enrolled1 locationNCT04988009
Recruiting
Phase 1

CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children

Malignant Brain NeoplasmRecurrent Malignant Brain NeoplasmRefractory Malignant Brain Neoplasm
City of Hope Medical Center18 enrolled3 locationsNCT04510051
Recruiting
Not Applicable

Ommaya Reservoir Placement at the Time of Biopsy for Longitudinal Biomarker Collection in Patients With Brain Tumors

Brain Neoplasms
Mayo Clinic20 enrolled1 locationNCT06322602
Recruiting
Not Applicable

OT SMILE: Occupational Therapy Group Intervention for Primary Brain Tumour Patients

Brain NeoplasmsGlioblastomaPrimary Brain Tumour
Royal College of Surgeons, Ireland96 enrolled1 locationNCT07426848
Recruiting
Phase 2

Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial

Malignant Brain NeoplasmMeningiomaLow-grade Glioma+1 more
Emory University200 enrolled1 locationNCT06132685