Bupivacaine Clinical Trials

8 recruiting

Bupivacaine Trials at a Glance

20 actively recruiting trials for bupivacaine are listed on ClinicalTrialsFinder across 6 cities in 6 countries. The largest study group is Not Applicable with 17 trials, with the heaviest enrollment activity in Beijing, Cairo, and Jinan. Lead sponsors running bupivacaine studies include Beijing Tiantan Hospital, Ain Shams University, and Cairo University.

Browse bupivacaine trials by phase

Treatments under study

About Bupivacaine Clinical Trials

Looking for clinical trials for Bupivacaine? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Bupivacaine trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Bupivacaine clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 20 trials

Recruiting
Not Applicable

Liposomal Bupivacaine Versus Ropivacaine With Perineural Dexamethasone or Dexmedetomidine as Adjuncts for Adductor Canal Block Combined With IPACK Block in Total Knee Arthroplasty

Nerve BlockLiposomal BupivacaineTotal Knee Anthroplasty+1 more
Huazhong University of Science and Technology90 enrolled1 locationNCT07509866
Recruiting
Not Applicable

Intrathecal Dexmedetomidine With Bupivacaine, in Patients Undergoing Knee Orthopedic Surgery

BupivacaineIntrathecal DexmedetomidineKnee Orthopedic Surgery
Cairo University120 enrolled1 locationNCT07522736
Recruiting
Not Applicable

Dexmedetomidine as an Adjuvant During Dural Puncture Epidural

Total Dose of Bupivacaine Administered During Labor
Menoufia University140 enrolled1 locationNCT07506044
Recruiting
Not Applicable

The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Laparoscopic Surgery

Laparoscopic SurgeryLiposomal BupivacaineLocal Infiltration
Beijing Tiantan Hospital190 enrolled1 locationNCT07458256
Recruiting
Not Applicable

The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery

Laparoscopic SurgeryLiposomal BupivacaineTransversus Abdominis Plane Block
Beijing Tiantan Hospital318 enrolled1 locationNCT07458282
Recruiting
Not Applicable

The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery in Gynecologic Oncology

Laparoscopic SurgeryLiposomal BupivacaineTransversus Abdominis Plane Block+1 more
Beijing Tiantan Hospital110 enrolled1 locationNCT07458295
Recruiting
Not Applicable

Impact of Bupivacaine Dilution With Dextrose or Saline on Infraclavicular Block Outcomes

BupivacaineInfraclavicular Brachial Plexus BlockDextrose+1 more
Burçin Alaçam, MD90 enrolled1 locationNCT07386327
Recruiting
Not Applicable

The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Video-assisted Thoracoscopic Surgery

Pain ManagementVideo-assisted Thoracoscopic Surgery (VATS)Liposomal Bupivacaine+1 more
Beijing Tiantan Hospital100 enrolled1 locationNCT07432711
Recruiting
Not Applicable

The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Hemorrhoid Surgery

Pain ManagementLocal InfiltrationHemorrhoid Surgery+1 more
Beijing Tiantan Hospital156 enrolled1 locationNCT07442539
Recruiting
Not Applicable

The Efficacy and Safety of Liposomal Bupivacaine for Rhomboid Intercostal Nerve Block in Relieving Postoperative Pain After Video-assisted Thoracoscopic Surgery

Pain ManagementVideo-assisted Thoracoscopic Surgery (VATS)Liposomal Bupivacaine+1 more
Beijing Tiantan Hospital134 enrolled1 locationNCT07441902
Recruiting
Not Applicable

Liposomal Bupivacaine Versus Ropivacaine for Preperitoneal Infiltration Analgesia in Upper Abdominal Laparotomy

AnalgesiaLiposomal BupivacainePreperitoneal Infiltration
Qilu Hospital of Shandong University146 enrolled1 locationNCT07271979
Recruiting
Not Applicable

Ultrasound Guided TAPB vs Surgical TAPB With Bupivacaine in Cesarean Section

BupivacaineAcute PainCesarean Section+2 more
Al-Azhar University50 enrolled1 locationNCT05750992
Recruiting
Not Applicable

Intrathecal Dexmedetomidine-Fentanyl Combination Versus Fentanyl Alone as Adjuvant to Bupivacaine in Spinal Anesthesia for Above Knee Amputation in Sarcomas of Lower Extremity

DexmedetomidineSarcomasIntrathecal+5 more
National Cancer Institute, Egypt58 enrolled1 locationNCT07276867
Recruiting
Phase 3

Analgesic Efficacy of Different Liposomal Bupivacaine Doses in the Adductor Canal Block for Total Knee Arthroplasty

Pain, PostoperativeTotal Knee ArthroplastyLiposomal Bupivacaine+2 more
The University of Hong Kong177 enrolled1 locationNCT06740214
Recruiting
Phase 4

Determination of the Optimal Volume of Liposomal Bupivacaine in Adductor Canal Block for Knee Joint Surgery

Optimal Volume of Liposomal Bupivacaine
Nanjing First Hospital, Nanjing Medical University63 enrolled1 locationNCT06942689
Recruiting
Not Applicable

Dexmedetomidine as an Adjuvant to Bupivacaine in Scalp Block Versus Bupivacaine Alone for Postoperative Pain Management in Patients Undergoing Craniotomy

Postoperative PainDexmedetomidineAdjuvant+3 more
Ain Shams University50 enrolled1 locationNCT06993922
Recruiting
Not Applicable

Local LevoBupivacaine for Pain Relief After Endoscopic Submucosal Dissection for Esophageal Lesions

Endoscopic Submucosal DissectionLevobupivacaine
Laura Boer88 enrolled3 locationsNCT06611176
Recruiting
Early Phase 1

Testing the Feasibility of Using Ropivacaine in Spinal Anesthesia for Patients With Lower Back Surgery

NeurosurgeryBupivacaineAnesthesia, Spinal+1 more
Fraser Health45 enrolled2 locationsNCT05824338
Recruiting
Not Applicable

Lignocaine vs Bupivacaine Infiltration for Postpartum Perineal Pain After Vaginal Delivery With Episiotomy in Primigravidae

BupivacaineLignocainePostpartum Perineal Pain
Ain Shams University60 enrolled1 locationNCT06568289
Recruiting
Not Applicable

Analgesic Efficacy of an Intermediate CPB in Neck Surgeries.

AnesthesiaThyroidBupivacaine+1 more
Cairo University54 enrolled1 locationNCT06419556