Cardiomyopathy Clinical Trials in London

17 recruitingLondon, United Kingdom

Showing 117 of 17 trials

Recruiting
Phase 3

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals1,250 enrolled233 locationsNCT07052903
Recruiting
Phase 2Phase 3

A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy

Symptomatic Genetic Dilated Cardiomyopathy
Kardigan, Inc.332 enrolled43 locationsNCT07210723
Recruiting
Phase 3

CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Novo Nordisk A/S1,280 enrolled290 locationsNCT07207811
Recruiting
Phase 2

A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc.165 enrolled67 locationsNCT07023614
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy

Non-obstructive Hypertrophic CardiomyopathyObstructive Cardiomyopathy, Hypertrophic
Lexicon Pharmaceuticals500 enrolled108 locationsNCT06481891
Recruiting
Phase 3

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

CardiomyopathiesAmyloidosisHeart Diseases+3 more
Eidos Therapeutics, a BridgeBio company587 enrolled101 locationsNCT06563895
Recruiting

AIC Genotyping Study

CardiomyopathyAtrial Fibrillation (AF)Genetic
Barts & The London NHS Trust299 enrolled1 locationNCT07574697
Recruiting
Phase 2Phase 3

A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

PediatricSymptomatic Obstructive Hypertrophic Cardiomyopathy
Cytokinetics55 enrolled38 locationsNCT06412666
Recruiting
Phase 3

MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Intellia Therapeutics1,200 enrolled132 locationsNCT06128629
Recruiting

HCMR Re-Imaging Study

Hypertrophic Cardiomyopathy (HCM)
Christopher Kramer314 enrolled8 locationsNCT07054073
Recruiting

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Transthyretin-Related (ATTR) Familial Amyloid CardiomyopathyTransthyretin-Related (ATTR) Familial Amyloid PolyneuropathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics72 enrolled4 locationsNCT05697861
Recruiting
Phase 2

Use of Bone Marrow Derived Stem Cell and G-CSF With Circulatory Assistance in the Treatment of DCM

Dilated Cardiomyopathy
Barts & The London NHS Trust20 enrolled1 locationNCT03572660
Recruiting

Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy

Cardiomyopathy
Tenaya Therapeutics200 enrolled29 locationsNCT05112237
Recruiting

Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

Arrhythmogenic Right Ventricular Cardiomyopathy
Tenaya Therapeutics200 enrolled21 locationsNCT06311708
Recruiting
Not Applicable

Physiological Versus Right Ventricular Outcome Trial Evaluated for Bradycardia Treatment Upgrades

Heart FailurePacing-Induced Cardiomyopathy
Imperial College London155 enrolled12 locationsNCT06052475
Recruiting
Not Applicable

Therapy to Maintain Remission in Dilated Cardiomyopathy

Heart FailureCardiomyopathiesHeart Diseases+1 more
Imperial College London50 enrolled1 locationNCT06091475
Recruiting

The SMARTER Cardiomyopathy Study

CardiomyopathiesHypertrophic CardiomyopathyDilated Cardiomyopathy
Imperial College London1,000 enrolled2 locationsNCT05750147