Phase 3 Complication Clinical Trials

45 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 45 trials

Recruiting
Phase 3

RECOMMEND Platform Trial

Intensive Care MedicineCritical IllnessCardiac Arrest (CA)+2 more
Australian and New Zealand Intensive Care Research Centre600 enrolled3 locationsNCT06526533
Recruiting
Phase 3

Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures

Wound HealWound ComplicationWound Dehiscence+2 more
Major Extremity Trauma Research Consortium352 enrolled6 locationsNCT06337292
Recruiting
Phase 3

meChANisms and sAfety of SGLT2 Inhibition in peRitoneal dialYsis

Kidney DysfunctionEnd-stage Kidney DiseasePeritoneal Dialysis Complication+2 more
University Health Network, Toronto20 enrolled1 locationNCT05715814
Recruiting
Phase 3

Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery

DeliriumSurgery--Complications
Washington University School of Medicine46 enrolled1 locationNCT06969287
Recruiting
Phase 3

"Continuous Positive Airway Pressure on Venovenous extracorporeaL Membrane Oxygenation for Acute respIratory Distress syndrOme"

Acute Respiratory Distress SyndromeExtracorporeal Membrane Oxygenation Complication
Assistance Publique - Hôpitaux de Paris280 enrolled11 locationsNCT06814340
Recruiting
Phase 3

Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial

cesarean deliveryObstetrical ComplicationsLabor and Delivery Complication
The George Washington University Biostatistics Center8,000 enrolled14 locationsNCT06605118
Recruiting
Phase 3

Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial

Preterm deliveryObstetrical Complications
The George Washington University Biostatistics Center1,800 enrolled14 locationsNCT06980025
Recruiting
Phase 3

Kidney Transplant Preemptive Therapy or Prophylaxis for CMV Prevention in D+R Recipients

Kidney Transplant; ComplicationsKidney DiseasesCytomegalovirus (CMV)
University of California, San Francisco360 enrolled5 locationsNCT06798909
Recruiting
Phase 3

A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD)Solid Organ Transplant ComplicationsLymphoproliferative Disorders+2 more
Pierre Fabre Medicament115 enrolled71 locationsNCT03394365
Recruiting
Phase 3

Local Antibiotics for Breast Implants

Implant ComplicationImplant InfectionAntibiotic Side Effect+4 more
Mikkel Herly1,003 enrolled8 locationsNCT04731025
Recruiting
Phase 3

Safest Choice of Antihypertensive Regimen for Postpartum Hypertension

Postpartum ComplicationHigh Blood PressureMaternal Hypertension
Loma Linda University500 enrolled1 locationNCT05551104
Recruiting
Phase 3

PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

InfectionsInjury LegAmputation+6 more
Major Extremity Trauma Research Consortium250 enrolled13 locationsNCT05699174
Recruiting
Phase 3

Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)

AnesthesiaAnesthesia ComplicationAnesthesia; Reaction+3 more
University of Texas Southwestern Medical Center200 enrolled1 locationNCT05358535
Recruiting
Phase 2Phase 3

Anticoagulation-free VV ECMO for Acute Respiratory Failure

Extracorporeal Membrane Oxygenation Complication
Damian Ratano40 enrolled1 locationNCT04273607
Recruiting
Phase 2Phase 3

Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women

DepressionAnxietyInflammation+9 more
Cedars-Sinai Medical Center150 enrolled1 locationNCT05552053
Recruiting
Phase 3

Feasibility of Enhanced Recovery After Surgery Without Prophylactic Abdominal Drainage Tubes After Laparoscopic Distal Gastrectomy For Gastric Cancer

Gastric AdenocarcinomaComplicationsLaparoscopic Gastrectomy
Zuoyi Jiao454 enrolled6 locationsNCT07029269
Recruiting
Phase 3

Darbepoetin in Patients Candidates for Liver Transplant. (EPO-LT Trial)

Liver Transplant; Complications
Fundacion Clinic per a la Recerca Biomédica140 enrolled1 locationNCT07169643
Recruiting
Phase 2Phase 3

IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study

Surgery--ComplicationsIron-deficiencySpinal Fusion+4 more
Columbia University120 enrolled1 locationNCT07217873
Recruiting
Phase 3

The Effect of Discontinuation of Renin Angiotensin System Inhibitors on the Perioperative Myocardial Injury in Adult Patients Undergoing Colorectal Cancer Surgery

Perioperative/Postoperative ComplicationsMyocardium; InjuryAngiotensin-Converting-Enzyme Inhibitor
Kasr El Aini Hospital156 enrolled1 locationNCT06862115
Recruiting
Phase 3

Early Specialized Cardiovascular Intervention Based on Impedance Cardiography in Locally Advanced Non-small Cell Lung Cancer Patients

Non-small Cell Lung CancerCardiovascular Complication
Sun Yat-sen University524 enrolled1 locationNCT04980716