Disease Clinical Trials in Philadelphia, Pennsylvania

256 recruitingPhiladelphia, Pennsylvania

Showing 120 of 256 trials

Recruiting
Phase 2

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

Central Nervous System DiseasesBrain CancerGlioblastoma Multiforme (GBM)+4 more
Black Diamond Therapeutics, Inc.162 enrolled22 locationsNCT07326566
Recruiting
Phase 3

Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)

Von Hippel-Lindau DiseaseMalignant Neoplasms
Merck Sharp & Dohme LLC450 enrolled46 locationsNCT07405164
Recruiting
Phase 2

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

Pancreatic Neuroendocrine TumorVon Hippel-Lindau DiseasePheochromocytoma/Paraganglioma+2 more
Merck Sharp & Dohme LLC355 enrolled84 locationsNCT04924075
Recruiting
Phase 3

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Cardiovascular DiseasesHypertensionDiabetes Mellitus, Type 2
Boehringer Ingelheim11,800 enrolled1154 locationsNCT07064473
Recruiting
Phase 3

A Long-term Extension Study of PCI-32765 (Ibrutinib)

Diffuse Large B Cell LymphomaChronic Lymphocytic LeukemiaMantle Cell Lymphoma+4 more
Janssen Research & Development, LLC700 enrolled175 locationsNCT01804686
Recruiting

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

Hodgkin LymphomaNon-Hodgkin LymphomaHematologic Malignancies+14 more
Center for International Blood and Marrow Transplant Research99,999 enrolled142 locationsNCT01351545
Recruiting

Fabry Disease Registry & Pregnancy Sub-registry

Fabry Disease
Genzyme, a Sanofi Company9,000 enrolled284 locationsNCT00196742
Recruiting
Phase 1

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmRheumatoid Arthritis+11 more
National Cancer Institute (NCI)300 enrolled52 locationsNCT03816345
Recruiting
Phase 2

TERPS Trial for de Novo Oligometastic Prostate Cancer

Prostate CancerOligometastatic Disease
University of Maryland, Baltimore122 enrolled10 locationsNCT05223803
Recruiting
Phase 3

A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD)Solid Organ Transplant ComplicationsLymphoproliferative Disorders+2 more
Pierre Fabre Medicament115 enrolled71 locationsNCT03394365
Recruiting

A Registry for People With T-cell Lymphoma

T-cell LymphomaNK-Cell LymphomaT-cell Prolymphocytic Leukemia+27 more
Memorial Sloan Kettering Cancer Center1,000 enrolled26 locationsNCT05978141
Recruiting
Phase 1Phase 2

A Study of Subcutaneous Blinatumomab in Children With R/R and and MRD+ B-Cell Precursor Acute Lymphoblastic Leukemia

Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic LeukemiaMinimal Residual Disease + B-Cell Acute Lymphoblastic Leukemia
Amgen104 enrolled4 locationsNCT07134088
Recruiting
Phase 1

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

Triple-Negative Breast CancerGastric CancerOvarian Cancer+25 more
NiKang Therapeutics, Inc.150 enrolled19 locationsNCT06586957
Recruiting
Phase 3

Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy

Neuroendocrine TumorsGep NetCarcinoid Tumor+4 more
RayzeBio, Inc.338 enrolled54 locationsNCT05477576
Recruiting

Leveraging Lung Cancer Screening to Optimize Screening Outcomes and COPD Management: COPD in LCS Registry

Chronic Obstructive Pulmonary DiseaseCOPD
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University420 enrolled1 locationNCT06974981
Recruiting

Transformative Research in Diabetic Nephropathy 2.0

Diabetes Mellitus, Type 2Kidney DiseasesDiabetic Nephropathies+1 more
University of Pennsylvania200 enrolled1 locationNCT07444203
Recruiting

Healthy Volunteers Study

Ovarian CancerGenetic Predisposition to Disease
Abramson Cancer Center at Penn Medicine50 enrolled1 locationNCT06962059
Recruiting
Not Applicable

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

ParagangliomaPheochromocytomaGenetic Predisposition+7 more
University of Pennsylvania1,000 enrolled1 locationNCT06377033
Recruiting

Temple Health Chest Initiative (THCI 2.0)

Chronic Obstructive Pulmonary Disease (COPD)
Temple University1,000 enrolled1 locationNCT06933758
Recruiting

Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS)

Congenital Central Hypoventilation SyndromeCongenital Central HypoventilationCCHS+3 more
Debra Weese-Mayer1,000 enrolled4 locationsNCT03568669