Diseases Clinical Trials in Boston, Massachusetts

82 recruitingBoston, Massachusetts

Showing 120 of 82 trials

Recruiting
Phase 3

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

CardiomyopathiesAmyloidosisHeart Diseases+3 more
Eidos Therapeutics, a BridgeBio company587 enrolled101 locationsNCT06563895
Recruiting
Phase 1

A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases

Refractory Autoimmune Diseases
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company125 enrolled28 locationsNCT07115745
Recruiting
Phase 1

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

Triple-Negative Breast CancerGastric CancerOvarian Cancer+25 more
NiKang Therapeutics, Inc.150 enrolled19 locationsNCT06586957
Recruiting

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

Hodgkin LymphomaNon-Hodgkin LymphomaHematologic Malignancies+14 more
Center for International Blood and Marrow Transplant Research99,999 enrolled142 locationsNCT01351545
Recruiting
Phase 1Phase 2

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Breast NeoplasmsBreast DiseasesNeoplasms+5 more
Stemline Therapeutics, Inc.73 enrolled86 locationsNCT05386108
Recruiting
Phase 4

GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH

Genetic PredispositionType 2 DiabetesMetabolic Diseases
Massachusetts General Hospital125 enrolled1 locationNCT06003153
Recruiting
Not Applicable

Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections

Postoperative ComplicationsAnastomotic LeaksAnastomotic Complication+8 more
Medtronic - MITG137 enrolled8 locationsNCT07351071
Recruiting
Phase 2

A Study to Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases

LeiomyosarcomaSolid Organ Transplant ComplicationsLymphoproliferative Disorders+8 more
Pierre Fabre Medicament190 enrolled40 locationsNCT04554914
Recruiting
Phase 3

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

Mitochondrial DiseasesMaternally Inherited Diabetes and Deafness (MIDD)Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)+1 more
Khondrion BV220 enrolled10 locationsNCT06451757
Recruiting
Not Applicable

A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule

Lynch SyndromeHealthyInflammatory Bowel Diseases+1 more
Massachusetts General Hospital30 enrolled1 locationNCT07219537
Recruiting
Not Applicable

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

Insulin Sensitivity/ResistanceObesityInsulin Resistance+16 more
Pichamol Jirapinyo, MD, MPH132 enrolled2 locationsNCT06138821
Recruiting

EVOC - EVs in Obesity and Cardiometabolic Disease

Cardiovascular Diseases
Massachusetts General Hospital100 enrolled1 locationNCT06408961
Recruiting
Not Applicable

Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance

HealthyInflammatory Bowel DiseasesCrohn Disease
Massachusetts General Hospital10 enrolled1 locationNCT07033208
Recruiting
Not Applicable

HEME Home Transfusion Program

LymphomaLeukemiaHematologic Malignancy+3 more
Dana-Farber Cancer Institute700 enrolled2 locationsNCT06487247
Recruiting
Not Applicable

Bladder Fiducial Markers and Multiparametric-MRI (Mp-MRI) to Optimize Bladder Chemo-radiotherapy

Bladder CancerNeoplasmsUrinary Bladder Neoplasm+2 more
Cedars-Sinai Medical Center60 enrolled3 locationsNCT04442724
Recruiting
Not Applicable

CV CARE: CardioVascular Care in PC Patients

Prostate CancerCardiovascular Diseases
Dana-Farber Cancer Institute180 enrolled2 locationsNCT06202820
Recruiting

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

Lung CancerCancer RiskCancer Predisposition Syndrome+28 more
Dana-Farber Cancer Institute5,000 enrolled1 locationNCT05463796
Recruiting
Phase 1Phase 2

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

Advanced Solid TumorsCarcinomaNeoplasms+9 more
Marengo Therapeutics, Inc.365 enrolled32 locationsNCT05592626
Recruiting

Investigating Hereditary Risk In Thoracic Cancers (INHERIT)

Lung CancerGenetic DiseaseHereditary Diseases+1 more
Dana-Farber Cancer Institute500 enrolled2 locationsNCT05587439
Recruiting
Early Phase 1

Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease

Chronic Kidney DiseasesType 2 Diabetes
Brigham and Women's Hospital125 enrolled1 locationNCT06190158