Frontotemporal Lobar Degeneration Clinical Trials

5 recruiting

Frontotemporal Lobar Degeneration Trials at a Glance

8 actively recruiting trials for frontotemporal lobar degeneration are listed on ClinicalTrialsFinder across 6 cities in 5 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Philadelphia, Seattle, and Austin. Lead sponsors running frontotemporal lobar degeneration studies include University of Pennsylvania, Mayo Clinic, and Centre Hospitalier Universitaire Dijon.

Browse frontotemporal lobar degeneration trials by phase

Treatments under study

About Frontotemporal Lobar Degeneration Clinical Trials

Looking for clinical trials for Frontotemporal Lobar Degeneration? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Frontotemporal Lobar Degeneration trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Frontotemporal Lobar Degeneration clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting

UPenn Observational Research Repository on Neurodegenerative Disease

Primary Progressive Aphasia(PPA)Frontotemporal Degeneration(FTD)Familial Frontotemporal Lobar Degeneration (fFTLD)+2 more
University of Pennsylvania1,000 enrolled1 locationNCT04715399
Recruiting
Not Applicable

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

DementiaAlzheimer DiseaseCommunication Disorders+11 more
University of Texas at Austin60 enrolled3 locationsNCT05741853
Recruiting
Phase 3

PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620

Alzheimer DiseaseFrontotemporal Lobar DegenerationCognitively Normal
University of Pennsylvania72 enrolled1 locationNCT05456503
Recruiting
Not Applicable

Single-centre Descriptive Study of Taste in Frontotemporal Lobar Degeneration Through the Analysis of Taste Evoked Potentials

Frontotemporal Lobar Degeneration (FTLD)
Centre Hospitalier Universitaire Dijon20 enrolled1 locationNCT07110207
Recruiting

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

Amyotrophic Lateral SclerosisCorticobasal Degeneration (CBD)Progressive Supranuclear Palsy (PSP)+11 more
Mayo Clinic2,100 enrolled27 locationsNCT04363684
Recruiting
Not Applicable

Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers

Quality of LifeDementiaCognitive Dysfunction+14 more
University of Washington1,800 enrolled3 locationsNCT05596760
Recruiting
Not Applicable

The Skin as a Window to the Central Nervous System in Frontotempolar Lombar Degeneration

Frontotemporal Lobar Degeneration
Nantes University Hospital80 enrolled1 locationNCT06490822
Recruiting

Neurodegenerative Diseases Progression Markers (MARKERS-NDD)

Cognitive ImpairmentDementiaMultiple System Atrophy+15 more
Casa di Cura San Raffaele Cassino600 enrolled1 locationNCT06596746