Hypercortisolism Clinical Trials

7 recruitingLast updated: June 18, 2026

There are 7 actively recruiting hypercortisolism clinical trials across 4 countries. Studies span Not Applicable, Phase 2. Top locations include Bergen, Norway, Ann Arbor, Michigan, United States, Bethesda, Maryland, United States. Updated daily from ClinicalTrials.gov.


Hypercortisolism Trials at a Glance

7 actively recruiting trials for hypercortisolism are listed on ClinicalTrialsFinder across 6 cities in 4 countries. The largest study group is Not Applicable with 2 trials, with the heaviest enrollment activity in Bergen, Ann Arbor, and Bethesda. Lead sponsors running hypercortisolism studies include Haukeland University Hospital, Meyer Children's Hospital IRCCS, and National Cancer Institute (NCI).

Browse hypercortisolism trials by phase

Treatments under study

About Hypercortisolism Clinical Trials

Looking for clinical trials for Hypercortisolism? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Hypercortisolism trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Hypercortisolism clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 17 of 7 trials

Recruiting
Not Applicable

Endoscopic Ultrasound-guided Radiofrequency Ablation in Primary Aldosteronism

Primary AldosteronismHypercortisolismAldosterone-Producing Adenoma
Haukeland University Hospital60 enrolled1 locationNCT05368090
Recruiting
Not Applicable

REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD)

NeoplasiaOsteoporosisObesity, Overweight+6 more
Meyer Children's Hospital IRCCS100 enrolled1 locationNCT07412782
Recruiting
Phase 2

Evaluating the Functional Status of the Adrenal Glands With [68Ga]Ga-PentixaFor in Hyperaldosteronism and Hypercortisolism

HypercortisolismHyperaldosteronismCushing s Syndrome
National Cancer Institute (NCI)80 enrolled1 locationNCT06246357
Recruiting

Salivary Cortisol and Hypercortisolism in Type 2 Diabetes

Type 2 Diabetes (T2DM)Hypercortisolism
Shanghai 6th People's Hospital500 enrolled1 locationNCT07156370
Recruiting

A Block-and-Replace Therapy With Osilodrostat and Concomitant Glucocorticoid Replacement

Adrenal InsufficiencyHypercortisolismEndogenous Cushing Syndrome
University of Michigan12 enrolled1 locationNCT06430528
Recruiting

Impact of Adrenal IncidenTalomas and Possible Autonomous Cortisol Secretion on Cardiovascular and Metabolic Alterations

HypercortisolismAdrenal IncidentalomaAdrenal Tumor
University of Roma La Sapienza68 enrolled1 locationNCT04127552
Recruiting

Dynamic Hormone Profiling and Multimodal Data Capture in Primary Aldosteronism

Primary AldosteronismHypercortisolismMineralocorticoid Excess
Haukeland University Hospital80 enrolled1 locationNCT06495983