Larynx Clinical Trials

2 recruiting

Frequently Asked Questions

Common questions about Larynx clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 22 trials

Recruiting
Phase 2Phase 3

De-Intensification of Postoperative Radiotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck

Squamous Cell Carcinoma of the LarynxSquamous Cell Carcinoma of the OropharynxSquamous Cell Carcinoma of the Oral Cavity+1 more
University of Erlangen-Nürnberg Medical School508 enrolled1 locationNCT06030440
Recruiting

Immune Biomarker Study for Cisplatin-ineligible Patients Receiving Chemoradiotherapy With Docetaxel

Squamous Cell Carcinoma of OropharynxOral Cavity Squamous Cell CarcinomaLarynx Squamous Cell Carcinoma+1 more
University of Erlangen-Nürnberg Medical School250 enrolled1 locationNCT06947668
Recruiting
Phase 2

A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC)

Squamous Cell Carcinoma of Head and NeckOral Cavity CancerNasal Cavity Cancer+9 more
Memorial Sloan Kettering Cancer Center40 enrolled7 locationsNCT07063212
Recruiting
Not Applicable

Predicting Post Extubation Stridor After Maxillomandibular Fixation

StridorLarynx Edema
Mansoura University62 enrolled1 locationNCT05839756
Recruiting
Not Applicable

Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck

Tongue CancerRecurrent Adenoid Cystic Carcinoma of the Oral CavityRecurrent Mucoepidermoid Carcinoma of the Oral Cavity+48 more
Ohio State University Comprehensive Cancer Center600 enrolled1 locationNCT01473784
Recruiting
Not Applicable

Accuracy of the Sensory Test Using the Laryngopharyngeal Endoscopic Esthesiometer in Obstructive Sleep Apnea

Sensory DisorderSleep Apnea, ObstructiveLarynx
Fundación Neumologica Colombiana117 enrolled2 locationsNCT03109171
Recruiting
Not Applicable

Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy

Head and Neck CancerHead and Neck Squamous Cell CarcinomaOral Cavity Cancer+2 more
Medical University of South Carolina532 enrolled4 locationsNCT05793151
Recruiting
Phase 3

Lymphocyte-Sparing And Radio-Immunotherapy in Head and Neck Carcinoma

Oropharynx CancerLarynx CancerHypopharynx Cancer+1 more
Centre Leon Berard460 enrolled7 locationsNCT06706401
Recruiting
Phase 1

Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Laryngeal Cancer

Malignant Neoplasms of Respiratory and Intrathoracic OrgansSquamous Cell Carcinoma of the Larynx
M.D. Anderson Cancer Center11 enrolled1 locationNCT03114462
Recruiting

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

CancerCancer, BreastCarcinoma+19 more
Massive Bio, Inc.50,000 enrolled68 locationsNCT03452774
Recruiting
Not Applicable

VoiceS: Voice Quality After Transoral CO2-Laser Surgery Versus Single Vocal Cord Irradiation for Larynx Cancer

Glottis TumorLarynx Cancer
Olgun Elicin34 enrolled4 locationsNCT04057209
Recruiting
Early Phase 1

Window Trial of Fluorescently Labeled Panitumumab (Panitumumab-IRDye800) in Head and Neck Cancer

HNSCCSCC - Squamous Cell CarcinomaHNSCC,Larynx, Pharynx and Oral Cavity
Vanderbilt-Ingram Cancer Center18 enrolled1 locationNCT06819228
Recruiting
Not Applicable

High-Resolution PET-CT Imaging for Surgical Margin Visualization

CancerHNSCCSCC - Squamous Cell Carcinoma+2 more
Vanderbilt-Ingram Cancer Center50 enrolled1 locationNCT06915454
Recruiting
Not Applicable

Proactive Risk-based Optimization & Notifications for Treatment & Outcomes in Head & Neck Cancer

Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity CancerHead &Amp;Amp; Neck Squamous Cell CarcinomaLarynx Squamous Cell Carcinoma
Centre hospitalier de l'Université de Montréal (CHUM)85 enrolled1 locationNCT07180901
Recruiting
Phase 1Phase 2

RAPA-201 Therapy of Solid Tumors

Head and Neck CancerEsophageal Squamous Cell CarcinomaSolid Tumor+6 more
Rapa Therapeutics LLC37 enrolled1 locationNCT05144698
Recruiting

Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy

HNSCCOral Cavity CancerOropharynx Cancer+2 more
University Hospital Freiburg1,500 enrolled18 locationsNCT05337631
Recruiting

Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome

Squamous Cell Carcinoma of the LarynxSquamous Cell Carcinoma of the OropharynxSquamous Cell Carcinoma of the Oral Cavity+1 more
AIO-Studien-gGmbH120 enrolled2 locationsNCT06380686
Recruiting
Phase 2

European Larynx Organ Preservation Study (ELOS) [MK-3475-C44]

Squamous Cell Carcinoma of Head and NeckLaryngeal CancerSquamous Cell Carcinoma of Larynx+9 more
University of Leipzig140 enrolled9 locationsNCT06137378
Recruiting
Not Applicable

Voice Outcome of Glottoplasty, Cricothyroid Approximation, Thyroplasty, and Chondrolaryngoplasty

SurgeryGender DysphoriaTransgenderism+1 more
University Ghent290 enrolled2 locationsNCT06439290
Recruiting
Phase 2

Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal Cancer

Hypopharyngeal CancerLarynx Cancer
Fudan University82 enrolled1 locationNCT06039631