LMA Clinical Trials

34 recruitingLast updated: May 13, 2026

There are 34 actively recruiting lma clinical trials across 35 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 3. Top locations include Chicago, Illinois, United States, Paris, France, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


LMA Trials at a Glance

34 actively recruiting trials for lma are listed on ClinicalTrialsFinder across 6 cities in 35 countries. The largest study group is Not Applicable with 6 trials, with the heaviest enrollment activity in Chicago, Paris, and Boston. Lead sponsors running lma studies include Assistance Publique - Hôpitaux de Paris, IRCCS Eugenio Medea, and Ionis Pharmaceuticals, Inc..

Browse lma trials by phase

Treatments under study

About LMA Clinical Trials

Looking for clinical trials for LMA? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new LMA trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about LMA clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 34 trials

Recruiting
Phase 3

REVEAL: A Phase 3 Study of ION582 in Angelman Syndrome

Angelman Syndrome
Ionis Pharmaceuticals, Inc.158 enrolled38 locationsNCT06914609
Recruiting
Phase 2

A Safety and Efficacy Study of GTX-102 in Subjects With Deletion- or Nondeletion-type Angelman Syndrome (AS)

Angelman Syndrome
Ultragenyx Pharmaceutical Inc60 enrolled22 locationsNCT07157254
Recruiting

A Natural History Study of Angelman Syndrome

Angelman Syndrome
Massachusetts General Hospital40 enrolled1 locationNCT07417137
Recruiting

Clinical and Laboratory Study of Methylmalonic Acidemia

Inborn Errors of MetabolismOrganic AcidemiaMethylmalonic Acidemia
National Human Genome Research Institute (NHGRI)2,275 enrolled3 locationsNCT00078078
Recruiting

Registry of Patients Diagnosed With Lysosomal Storage Diseases

Mucopolysaccharidosis IMucopolysaccharidosis IIMucopolysaccharidosis VI+5 more
University of California, San Francisco250 enrolled1 locationNCT05619900
Recruiting
Phase 1

PEARL (PrEnAtal Enzyme Replacement Therapy for Lysosomal Storage Disorders)

Pompe Disease (Infantile-Onset)MPS VIIMPS I+6 more
University of California, San Francisco10 enrolled1 locationNCT04532047
Recruiting

Use of Eye Tracking to Study Social Perception Abnormalities in Children With Angelman Syndrome

Angelman Syndrome
Assistance Publique - Hôpitaux de Paris60 enrolled1 locationNCT06737718
Recruiting
Phase 1Phase 2

A Phase 1/2 Study of the Safety and Efficacy of MVX-220 in Angelman Syndrome

Angelman Syndrome
MavriX Bio, LLC12 enrolled3 locationsNCT07181837
Recruiting
Not Applicable

Effects of Continuous Monitoring and Progressive Regulation of Inflatable Laryngeal Mask Airway Cuff Pressure on Postoperative Pharyngolaryngeal Complications in Elderly Patients

Oropharyngeal leak pressureRandomized Controlled TrialElderly (People Aged 65 or More)+4 more
First Affiliated Hospital of Chongqing Medical University146 enrolled1 locationNCT07461467
Recruiting

Lysosomal Acid Lipase (LAL) Deficiency Registry

Lysosomal Acid Lipase DeficiencyWolman DiseaseCholesterol Ester Storage Disease+4 more
Alexion Pharmaceuticals, Inc.300 enrolled104 locationsNCT01633489
Recruiting

IDMet (RaDiCo Cohort) (RaDiCo-IDMet)

Beckwith-Wiedemann SyndromePrader-Willi SyndromePseudohypoparathyroidism+6 more
Institut National de la Santé Et de la Recherche Médicale, France2,000 enrolled20 locationsNCT05945576
Recruiting
Not Applicable

Web Intervention for Parents of Youth With Genetic Syndromes (WINGS)

Tuberous SclerosisFragile X SyndromeRett Syndrome+5 more
Rush University Medical Center92 enrolled1 locationNCT06139172
Recruiting
Phase 1Phase 2

An Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3705 in Participants Previously Enrolled in Other Clinical Studies of mRNA-3705

Methylmalonic Acidemia
ModernaTX, Inc.56 enrolled12 locationsNCT05295433
Recruiting
Phase 1Phase 2

HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome

Angelman Syndrome
Ionis Pharmaceuticals, Inc.70 enrolled11 locationsNCT05127226
Recruiting

Prevalence and Risk Factors asSOciated With CArdiac comorbiDIty in psoriAsis

Heart FailureCardiovascular DiseasesStroke+21 more
Herlev and Gentofte Hospital1,000 enrolled1 locationNCT04950218
Recruiting

The Molecular Basis of Inherited Reproductive Disorders

Kallmann SyndromeHypogonadotropic HypogonadismReproductive Disorder+1 more
Stephanie B. Seminara, MD600 enrolled1 locationNCT05971836
Recruiting
Not Applicable

The Influence of Standardized Process Management of Laryngeal Mask Airway Placement Based on Pressure Monitoring on the Incidence of Adverse Reactions in Elderly Patients During the Perioperative Period

pressure injuryElderlyAirway Management+1 more
Xuanqi Yang78 enrolled1 locationNCT06954857
Recruiting

Natural History Study for Patients With Angelman Syndrome

Angelman Syndrome
Centre Hospitalier Universitaire de Liege30 enrolled1 locationNCT06229769
Recruiting

An Observational Study of Carbaglu® for the Treatment of MMA and PA in Adults and Pediatrics

Propionic AcidemiaMethylmalonic AcidemiaHyperammonemia
RECORDATI GROUP20 enrolled5 locationsNCT05040178
Recruiting

The Osteoarticular Manifestations in Patients With Gitelman Syndrome

Gitelman SyndromeCPPD - Calcium Pyrophosphate Deposition Disease
Second Affiliated Hospital, School of Medicine, Zhejiang University120 enrolled1 locationNCT06922370