Phase 2 Merkel Cell Carcinoma Clinical Trials
16 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–16 of 16 trials
Recruiting
Phase 1Phase 2
Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic Melanoma+10 more
National Cancer Institute (NCI)16 enrolled26 locationsNCT05896839
Recruiting
Phase 1Phase 2
A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors
MelanomaNon-small Cell Lung CancerSquamous Cell Carcinoma (Skin)+2 more
AstraZeneca60 enrolled11 locationsNCT07115043
Recruiting
Phase 2
Phase II Study of Peptide Receptor Radionuclide Therapy in Combination With Immunotherapy for Patients With Merkel Cell Cancer
Merkel Cell Carcinoma
Weill Medical College of Cornell University18 enrolled3 locationsNCT05583708
Recruiting
Phase 2
At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Advanced Colorectal CarcinomaAdvanced Anal CarcinomaAdvanced Biliary Tract Carcinoma+41 more
Mayo Clinic220 enrolled2 locationsNCT05969860
Recruiting
Phase 2Phase 3
Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma
Advanced Or Metastatic Merkel Cell Carcinoma
TuHURA Biosciences, Inc.118 enrolled18 locationsNCT06947928
Recruiting
Phase 1Phase 2
Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Triple-Negative Breast Carcinoma+97 more
Mayo Clinic132 enrolled1 locationNCT05269381
Recruiting
Phase 2
EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin Cancers
Skin Squamous Cell CarcinomaMerkel Cell CarcinomaCutaneous Melanoma
Ohio State University Comprehensive Cancer Center100 enrolled1 locationNCT06223659
Recruiting
Phase 1Phase 2
Study to Investigate the Efficacy and Safety of RP1 in Adult Patients With Organ Transplants and Advanced Skin Malignancies
CancerMerkel Cell CarcinomaBasal Cell Carcinoma+1 more
Replimune, Inc.90 enrolled28 locationsNCT04349436
Recruiting
Phase 2
Neoadjuvant PD-1 Blockade in Resectable Merkel Cell Carcinoma
Merkel Cell Carcinoma
Abramson Cancer Center at Penn Medicine15 enrolled1 locationNCT05496036
Recruiting
Phase 2
Neoadjuvant Nivolumab and Relatlimab in Merkel Cell Carcinoma
Merkel Cell Carcinoma
Melanoma Institute Australia20 enrolled1 locationNCT06151236
Recruiting
Phase 2
TIL Therapy in cSCC and MCC
Merkel Cell CarcinomaCutaneous Squamous Cell CarcinomaSkin Cancer+1 more
Karam Khaddour, MD, MS14 enrolled1 locationNCT07288073
Recruiting
Phase 2
Hypofractionated Radiation Therapy for Merkel Cell Carcinoma
Merkel Cell Carcinoma
M.D. Anderson Cancer Center52 enrolled1 locationNCT05100095
Recruiting
Phase 2
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
Breast CarcinomaUrothelial CarcinomaOvarian Carcinoma+26 more
Mayo Clinic27 enrolled1 locationNCT07285044
Recruiting
Phase 2
Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus
Merkel Cell CarcinomaMalignant NeoplasmAcquired Immunodeficiency Syndrome+5 more
M.D. Anderson Cancer Center100 enrolled1 locationNCT02479698
Recruiting
Phase 1Phase 2
Targeted Therapy and Avelumab in Merkel Cell Carcinoma
Metastatic Merkel Cell Carcinoma
Melanoma and Skin Cancer Trials Limited19 enrolled10 locationsNCT04261855
Active
Phase 2
An efficacy study of Chemo-Radiotherapy in Positron Emission Tomography (PET) Merkel Cell Carcinoma of the Skin
Merkel Cell Carcinoma
Trans Tasman Radiation Oncology Group (TROG)50 enrolled13 locationsACTRN12610000480088