Muscle Atrophy Clinical Trials

22 recruitingLast updated: June 18, 2026

There are 22 actively recruiting muscle atrophy clinical trials across 10 countries. Studies span Not Applicable, Phase 2, Early Phase 1, Phase 1. Top locations include Boston, Massachusetts, United States, Mölndal, Sweden, Eugene, Oregon, United States. Updated daily from ClinicalTrials.gov.


Muscle Atrophy Trials at a Glance

22 actively recruiting trials for muscle atrophy are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 14 trials, with the heaviest enrollment activity in Boston, Mölndal, and Eugene. Lead sponsors running muscle atrophy studies include Sahlgrenska University Hospital, Tufts Medical Center, and University of Nottingham.

Browse muscle atrophy trials by phase

Treatments under study

About Muscle Atrophy Clinical Trials

Looking for clinical trials for Muscle Atrophy? There are currently 12 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Muscle Atrophy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Muscle Atrophy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 22 trials

Recruiting
Not Applicable

Postoperative Electrical Muscle Stimulation Two

Colorectal, CancerSurgeryMuscle Atrophy+1 more
University of Nottingham45 enrolled1 locationNCT06964438
Recruiting
Not Applicable

Impact of NMES and HPRO on Recovery After SAH- Pilot Study

InflammationSubarachnoid HemorrhageMuscle Atrophy+1 more
University of Maryland, Baltimore30 enrolled1 locationNCT03201094
Recruiting
Phase 2

TCM Formula vs. HMB in Pre-Frail Elders: Muscle Strength and Bone Status

pre frailtySarcopeniaOsteoporosis+2 more
Tri-Service General Hospital90 enrolled1 locationNCT07597850
Recruiting
Phase 2

Essential Amino Acid Supplementation for Femoral Fragility Fractures

Muscle AtrophyFragility FractureFemoral Fracture
Michael C Willey60 enrolled2 locationsNCT06050668
Recruiting
Not Applicable

Improved Muscle Metabolism by Combination of Muscle Activation and Protein Substitution ( IMEMPRO )

ICU acquired weaknessMetabolic DisturbanceQuality of Life+3 more
Technical University of Munich40 enrolled4 locationsNCT05919940
Recruiting

Clinimetric Properties of Muscle Mass and Stiffness Measurements of the Quadriceps in Patients With COPD

COPDQuadriceps Muscle Atrophy
Groupe Hospitalier du Havre30 enrolled1 locationNCT06994689
Recruiting
Not Applicable

The Impact of Blood Flow Restriction Training in Adolescents After ACL Reconstruction: A Randomized Controlled Trial

Knee injuriesQuadriceps Muscle AtrophyAnterior Cruciate Ligament Injuries
Connecticut Children's Medical Center40 enrolled1 locationNCT05754632
Recruiting
Early Phase 1

Metformin and Muscle Recovery

Muscle Atrophy or Weakness
University of Utah50 enrolled1 locationNCT06185179
Recruiting
Not Applicable

A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure

Heart FailureMuscle Atrophy
Tufts Medical Center120 enrolled2 locationsNCT05627440
Recruiting
Phase 1Phase 2

Safety and Tolerability of IMM01-STEM in Patients With Muscle Atrophy Related to Knee Osteoarthritis.

Muscle Atrophy
Immunis, Inc.28 enrolled2 locationsNCT05211986
Recruiting
Not Applicable

FIT Exercise in 30d of ULLS-induced Muscle Disuse

Muscle WeaknessMuscle Atrophy
Lance Bollinger16 enrolled1 locationNCT06631053
Recruiting
Not Applicable

Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury

Osteoarthritis, KneePost-traumatic OsteoarthritisQuadriceps Muscle Atrophy+1 more
University of North Carolina, Chapel Hill114 enrolled2 locationsNCT04875052
Recruiting
Not Applicable

C-Protein in Fatigue and Aging

SarcopeniaAgingMuscle Atrophy or Weakness+1 more
University of Oregon24 enrolled1 locationNCT05926219
Recruiting

Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure

Heart FailureCardiogenic ShockMuscle Atrophy+1 more
Tufts Medical Center60 enrolled1 locationNCT06253104
Recruiting
Not Applicable

Impacts of Mechanistic Target of Rapamycin (mTOR) Inhibition on Aged Human Muscle (Rapamune)

Muscle AtrophyAge-Related Sarcopenia
University of Nottingham16 enrolled1 locationNCT05414292
Recruiting
Not Applicable

The Role of Surgical Approach on Residual Limping After Total Hip Arthroplasty

Muscle WeaknessMuscle AtrophyArthroplasty Complications+2 more
Sahlgrenska University Hospital580 enrolled1 locationNCT05216666
Recruiting
Not Applicable

Achilles Tendon for the Treatment of Gluteus Medius Insufficiency

Muscle WeaknessMuscle AtrophyArthroplasty Complications+1 more
Sahlgrenska University Hospital44 enrolled1 locationNCT05206838
Recruiting
Not Applicable

Resistance Training, Detraining, and Retraining Study 2024 (TraDeRe2024)

Exercise TrainingHealthySkeletal Muscle Atrophy+1 more
University of Jyvaskyla90 enrolled1 locationNCT06573086
Recruiting
Phase 2

Vitamin D to Improve Quadricep Muscle Strength

Anterior cruciate ligament ruptureQuadriceps Muscle AtrophyAnterior Cruciate Ligament Injuries+1 more
Chinese University of Hong Kong60 enrolled1 locationNCT05174611
Recruiting
Not Applicable

The Role of Type 2 Diabetes on Skeletal Muscle Atrophy and Recovery Following Bed Rest in Older Adults

Sedentary BehaviorAgingType 2 Diabetes+2 more
AdventHealth Translational Research Institute50 enrolled1 locationNCT03761446