OAG Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about OAG clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 34 trials

Recruiting
Phase 2Phase 3

Study of QLS-111-FDC in Open-Angle Glaucoma or Ocular Hypertension

OAG - Open-Angle GlaucomaOHT - Ocular Hypertension
Qlaris Bio, Inc.36 enrolled1 locationNCT07354516
Recruiting
Not Applicable

Home Hospital for Suddenly Ill Adults

Heart FailureAsthmaChronic Kidney Diseases+6 more
Brigham and Women's Hospital3,000 enrolled2 locationsNCT03524222
Recruiting
Not Applicable

Aqueous Humor and Ocular Tissue Analysis in Glaucoma and Cataract

CataractPrimary Open Angle Glaucoma (POAG)
Military Institute od Medicine National Research Institute40 enrolled2 locationsNCT07462000
Recruiting
Phase 1

Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

Open-angle Glaucoma (OAG)NAION( Non-arteritic Anterior Ischemic Optic Neuropathy)
Life Biosciences Inc.18 enrolled2 locationsNCT07290244
Recruiting

UBM Evaluation After Combined Deep Sclerectomy With Trabeculotomy in Primary Open Angle Glaucoma

Primary Open Angle Glaucoma (POAG)
Minia University Hospital30 enrolled1 locationNCT07454447
Recruiting

The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing

Inflammatory Bowel DiseasesHeart DiseasesAutoimmune Disease+5 more
University of Chicago1,200 enrolled1 locationNCT01280825
Recruiting
Not Applicable

Clinical Trial to Evaluate the Safety and Effectiveness of a Canaloplasty Device in Subjects With Open-Angle Glaucoma

OAG - Open-Angle Glaucoma
New World Medical, Inc.70 enrolled3 locationsNCT05696561
Recruiting

Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcg

Ocular Hypertension (OH)Open-angle Glaucoma (OAG)
Glaukos Corporation30 enrolled1 locationNCT07400926
Recruiting
Phase 2

Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation

Normal Tension Glaucoma (NTG)Non-proliferative Diabetic Retinopathy (NPDR)Open-angle Glaucoma (OAG)
Qlaris Bio, Inc.14 enrolled1 locationNCT07354477
Recruiting
Not Applicable

Atrial Fibrillation TRIal of Left Atrial Appendage Closure Using Seralene Hemostatic Suture

Atrial Fibrillation (AF)Stroke (in Patients With Atrial Fibrillation)ATRIAL APPENDAGE CLOSURE for ATRIAL FIBRILLATION+2 more
Institute of Cardiovascular Diseases, Vojvodina200 enrolled1 locationNCT07360899
Recruiting
Not Applicable

Evaluation of BRUDYGLAUCO (DHA + Citicoline) in Patients With Glaucoma

GlaucomaPrimary Open Angle Glaucoma (POAG)Neuroprotection
Institut Catala de Retina108 enrolled2 locationsNCT07322965
Recruiting
Phase 3

Efficacy and Safety of HUC3-637 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Ocular HypertensionPrimary Open Angle Glaucoma (POAG)
Huons Co., Ltd.206 enrolled1 locationNCT07335211
Recruiting
Not Applicable

iStent Inject Versus Goniotomy With Kahook Dual Blade in Glauocma Treatment

Open-angle Glaucoma (OAG)
Medical University of Bialystok100 enrolled2 locationsNCT07325552
Recruiting
Phase 1

Evaluate Efficacy, Safety, Tolerability and Biodegradation of PA5346 Ocular Implant in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension (OH)Open-angle Glaucoma (OAG)
PolyActiva Pty Ltd12 enrolled3 locationsNCT06964061
Recruiting
Not Applicable

Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma

Open-angle Glaucoma (OAG)
Avisi Technologies Inc.165 enrolled12 locationsNCT07220876
Recruiting
Phase 4

A Study to Evaluate Adverse Events and Change in Disease Activity With the XEN45 Glaucoma Treatment System Implantation In Adult Participants With Open-Angle Glaucoma in China

Open Angle GlaucomaOAG
AbbVie130 enrolled13 locationsNCT05821855
Recruiting
Phase 1Phase 2

GVB-2001 Gene Therapy Via Intracameral Injection for the Treatment of Primary Open Angle Glaucoma

Primary Open Angle Glaucoma (POAG)
IVIEW Therapeutics Inc.12 enrolled1 locationNCT06921317
Recruiting
Phase 3

Thrombolysis in Factor Xa-inhibitors Trial

StrokeAcute Ischemic StrokeIschemic Stroke+6 more
Guri Hagberg300 enrolled13 locationsNCT06878066
Recruiting
Not Applicable

Direct Selective Laser Trabeculoplasty (DSLT) for Reducing Eye Pressure in Non-Caucasian Patients With Open Angle Glaucoma

Primary Open Angle Glaucoma (POAG)
Select Eye Care60 enrolled1 locationNCT07147647
Recruiting

DSLT Performance in Treatment-naïve Patients With Newly Diagnosed Open Angle Glaucoma

Open-angle Glaucoma (OAG)
Barnet Dulaney Perkins Eye Centers55 enrolled1 locationNCT06933836