Obstructive Clinical Trials in London

21 recruitingLondon, United Kingdom

Showing 120 of 21 trials

Recruiting
Phase 2

A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc.165 enrolled56 locationsNCT07023614
Recruiting

Pooled Analysis of Single-arm Studies of Budesonide/Glycopyrronium/Formoterol (BGF) in Routine Care Setting

Pulmonary Disease, Chronic Obstructive
AstraZeneca2,000 enrolled7 locationsNCT06712563
Recruiting
Phase 4

A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation

Chronic Obstructive Pulmonary DiseaseHyperinflation
AstraZeneca56 enrolled7 locationsNCT07073950
Recruiting
Phase 2Phase 3

A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

PediatricSymptomatic Obstructive Hypertrophic Cardiomyopathy
Cytokinetics55 enrolled38 locationsNCT06412666
Recruiting
Phase 3

Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)

Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline960 enrolled159 locationsNCT06961214
Recruiting
Phase 3

A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease
Hoffmann-La Roche2,000 enrolled483 locationsNCT05878769
Recruiting
Phase 3

A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)
Hoffmann-La Roche1,290 enrolled462 locationsNCT05595642
Recruiting
Phase 2

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)
AstraZeneca1,160 enrolled363 locationsNCT07082738
Recruiting
Phase 4

Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels

Chronic Obstructive Pulmonary Disease
Maria Joyera Rodríguez135 enrolled6 locationsNCT06334575
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy

Non-obstructive Hypertrophic CardiomyopathyObstructive Cardiomyopathy, Hypertrophic
Lexicon Pharmaceuticals500 enrolled107 locationsNCT06481891
Recruiting

EURO-STIM Registry

Obstructive Sleep ApneaObstructive Sleep Apnea (OSA)
Inspire Medical Systems, Inc.1,000 enrolled21 locationsNCT06971796
Recruiting
Phase 1

A Study for GSK3862995B in Healthy Participants and Participants With Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline130 enrolled32 locationsNCT06154837
Recruiting
Not Applicable

Reducing Chronic Breathlessness in Adults by Following a Self-guided, Internet Based Supportive Intervention (SELF-BREATHE)

Lung CancerAsthmaChronic Obstructive Pulmonary Disease+5 more
King's College Hospital NHS Trust246 enrolled1 locationNCT06326957
Recruiting
Not Applicable

Increasing the Use of an Anti-snoring Mouth Guard (Mandibular Advancement Appliance) to Prevent Upper Airway Collapse During Sleep in Patients With Obstructive Sleep Apnoea.

Obstructive Sleep Apnea
Queen Mary University of London56 enrolled1 locationNCT04092660
Recruiting

PASS to Assess Cardiovascular and Cerebrovascular Events in COPD Patients Initiating Fixed Triple Therapy (DPI or pMDI)

Chronic Obstructive Pulmonary Disease
Chiesi Farmaceutici S.p.A.25,000 enrolled1 locationNCT05652439
Recruiting

InvEstigating oeStrogen Signalling and the Effect upoN the exTracelluar Matrix In pAtients With Obstructive Lung Disease

AsthmaRespiratory IlnessEstrogen Deficiency+1 more
Guy's and St Thomas' NHS Foundation Trust100 enrolled1 locationNCT06713512
Recruiting

The CATALINA Study

Chronic Obstructive Pulmonary Disease Exacerbation
Wim Janssens1,000 enrolled18 locationsNCT05008081
Recruiting
Not Applicable

North West London Pebble Pathway: Automated OSA Diagnosis

Obstructive Sleep ApneaSleep Apnea
Patrik Bachtiger200 enrolled1 locationNCT06507228
Recruiting

Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure

Chronic Obstructive Pulmonary DiseaseRespiratory FailureNeuromuscular Diseases+1 more
Guy's and St Thomas' NHS Foundation Trust200 enrolled1 locationNCT04236726
Recruiting

The London COPD Exacerbation Cohort

Pulmonary Disease, Chronic Obstructive
Imperial College London300 enrolled1 locationNCT02755974