Opioid-Related Disorders Clinical Trials

9 recruitingLast updated: May 21, 2026

There are 9 actively recruiting opioid-related disorders clinical trials across 2 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3. Top locations include Baltimore, Maryland, United States, Boston, Massachusetts, United States, Columbus, Ohio, United States. Updated daily from ClinicalTrials.gov.


Opioid-Related Disorders Trials at a Glance

9 actively recruiting trials for opioid-related disorders are listed on ClinicalTrialsFinder across 6 cities in 2 countries. The largest study group is Not Applicable with 3 trials, with the heaviest enrollment activity in Baltimore, Boston, and Columbus. Lead sponsors running opioid-related disorders studies include Indiana University, National Institute on Drug Abuse (NIDA), and Badalona Serveis Assistencials.

Browse opioid-related disorders trials by phase

About Opioid-Related Disorders Clinical Trials

Looking for clinical trials for Opioid-Related Disorders? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Opioid-Related Disorders trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Opioid-Related Disorders clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting
Phase 1

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis

Pancreatic SurgeryChronic PainChronic Pancreatitis+7 more
Indiana University24 enrolled5 locationsNCT05603702
Recruiting

Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder

Drug addictionOpioid-Related Disorders
National Institute on Drug Abuse (NIDA)150 enrolled1 locationNCT03745339
Recruiting
Phase 3

Optimizing Chronic Pain Care With Mindfulness and Chronic Pain Management Visits

Prescription opioid misusePainChronic Pain+6 more
University of Utah300 enrolled3 locationsNCT06387290
Recruiting
Phase 2

Psilocybin in Cancer Pain Study

Advanced cancersAdvanced CancerPain Management+2 more
Yvan Beaussant, MD, MSci15 enrolled1 locationNCT06001749
Recruiting

fMRI and Opioid Abstinence

Opioid UseOpioid DependenceOpioid Abuse+2 more
Yale University240 enrolled1 locationNCT06651333
Recruiting
Not Applicable

Developing a Smartphone Application to Support Veteran Opioid Use Disorder Treatment

Quality of LifePsychosocial FunctioningOpioid-Related Disorders
VA Office of Research and Development75 enrolled1 locationNCT06454903
Recruiting
Phase 2

Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder

Magnetic Resonance ImagingEcological Momentary AssessmentAttentional Bias+4 more
University of Arkansas255 enrolled1 locationNCT05336188
Recruiting
Not Applicable

Clinical Trial on Deprescribing Associated With a Psychoeducational Program Using Virtual Reality for Patients With Chronic Pain and Central Sensitization

Chronic PainCentral SensitisationOpioid-Related Disorders+1 more
Badalona Serveis Assistencials72 enrolled4 locationsNCT06964360
Recruiting
Not Applicable

Developing and Evaluating a Machine-Learning Opioid Overdose Prediction & Risk-Stratification Tool in Primary Care

Opiate OverdoseOpioid-Related Disorders
University of Pittsburgh2,000 enrolled1 locationNCT06810076