Phase 2 Opioid Clinical Trials
50 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 50 trials
Recruiting
Phase 2
A Study of Brenipatide in Participants With Opioid Use Disorder
Opioid-use Disorder
Eli Lilly and Company465 enrolled57 locationsNCT07420283
Recruiting
Phase 2
Psilocybin on Brain Mechanisms of Motivation in OUD
Opioid-use Disorder
University of Pennsylvania24 enrolled1 locationNCT06810310
Recruiting
Phase 2
Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder
Opioid-use DisorderOpioid Use Disorder, ModerateOpioid Use Disorder, Severe
T. John Winhusen, PhD310 enrolled9 locationsNCT06651177
Recruiting
Phase 2Phase 3
Efficacy of Buprenorphine and XR-Naltrexone Combination for Relapse Prevention in Opioid Use Disorder
Opioid-use Disorder
New York State Psychiatric Institute180 enrolled2 locationsNCT05011266
Recruiting
Phase 2Phase 3
"Dexa vs Dexmedetomidine With Bupivacaine in TAP Block for Laparotomy Analgesia
Opioid UsePain, PostoperativeLaparotomy
Sahiwal medical college sahiwal96 enrolled1 locationNCT07590752
Recruiting
Phase 2
Evaluating Buspirone to Treat Opioid Withdrawal
AnxietyOpioid-use DisorderOpioid Withdrawal+1 more
University of Maryland, Baltimore100 enrolled1 locationNCT05511909
Recruiting
Phase 1Phase 2
Safety and Pharmacokinetics Study of Naldemedine in Paediatric Participants Receiving Opioids
Opioid-Induced Constipation (OIC)
Shionogi24 enrolled16 locationsNCT05588323
Recruiting
Phase 1Phase 2
Clinical Trials of Multivalent Opioid Vaccine Components
Opioid-use Disorder
New York State Psychiatric Institute45 enrolled2 locationsNCT04458545
Recruiting
Phase 2
Pain Alleviation With Testosterone in Opioid-Induced Hypogonadism
PainOpioid UseHypogonadism, Male
Brigham and Women's Hospital150 enrolled1 locationNCT04798469
Recruiting
Phase 2
Extended-release Buprenorphine as a Novel Low-dose Induction Strategy
Opioid-use Disorder
Brigham and Women's Hospital30 enrolled1 locationNCT06441604
Recruiting
Phase 2
Remotely Observed Methadone Evaluation II
Opioid-use Disorder
Sonara Health100 enrolled1 locationNCT06338280
Recruiting
Phase 2
MDMA for Co-occurring PTSD and OUD After Childbirth
Stress Disorders, Post-TraumaticOpioid-use Disorder
University of New Mexico15 enrolled1 locationNCT05219175
Recruiting
Phase 2
Ketamine for Opioid Use Disorder
Opioid-use Disorder
University of Maryland, Baltimore50 enrolled1 locationNCT06943859
Recruiting
Phase 2
E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder
Opioid-use DisorderCigarette Smoking
NYU Langone Health302 enrolled2 locationsNCT05722561
Recruiting
Phase 1Phase 2
A Bundled Intervention
Opioid-use DisorderOpioid Overdose
University of Alabama at Birmingham190 enrolled1 locationNCT06593093
Recruiting
Phase 2
Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal
Opioid UseOpiate Withdrawal Syndrome
University of Pennsylvania150 enrolled2 locationsNCT05995535
Recruiting
Phase 2Phase 3
Divided or Single Exposure (DOSE) Study
Chronic PainOpioid-use DisorderMethadone
University of Maryland, Baltimore150 enrolled1 locationNCT05459402
Recruiting
Phase 2
Psilocybin for Opioid Use Disorder (OUD)
Opioid-use Disorder
NYU Langone Health480 enrolled5 locationsNCT06796062
Recruiting
Phase 2
Combined THC and CBD for OUD and Chronic Pain
Chronic PainOpioid-use Disorder
Yale University147 enrolled1 locationNCT06544291
Recruiting
Phase 2
Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage
Opioid UseSubarachnoid Hemorrhage, AneurysmalHeadache+1 more
The University of Texas Medical Branch, Galveston15 enrolled1 locationNCT07294118