Phase 2 Opioid Clinical Trials
25 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 25 trials
Recruiting
Phase 1Phase 2
Safety and Pharmacokinetics Study of Naldemedine in Paediatric Participants Receiving Opioids
Opioid-Induced Constipation (OIC)
Shionogi24 enrolled16 locationsNCT05588323
Recruiting
Phase 1Phase 2
Clinical Trials of Multivalent Opioid Vaccine Components
Opioid-use Disorder
New York State Psychiatric Institute45 enrolled2 locationsNCT04458545
Recruiting
Phase 2
Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder
Magnetic Resonance ImagingEcological Momentary AssessmentAttentional Bias+4 more
University of Arkansas255 enrolled1 locationNCT05336188
Recruiting
Phase 2
Pain Alleviation With Testosterone in Opioid-Induced Hypogonadism
PainOpioid UseHypogonadism, Male
Brigham and Women's Hospital150 enrolled1 locationNCT04798469
Recruiting
Phase 2
Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal
Opioid UseOpiate Withdrawal Syndrome
University of Pennsylvania150 enrolled2 locationsNCT05995535
Recruiting
Phase 2
Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage
Opioid UseSubarachnoid Hemorrhage, AneurysmalHeadache+1 more
The University of Texas Medical Branch, Galveston15 enrolled1 locationNCT07294118
Recruiting
Phase 2
Opioid/Benzodiazepine Polydrug Abuse: Aim 3
Opioid AbusePolysubstance AbuseBenzodiazepine Abuse
Wayne State University24 enrolled1 locationNCT05006079
Recruiting
Phase 2
Psilocybin in Cancer Pain Study
Advanced CancerPain ManagementOpioid-Related Disorders+1 more
Yvan Beaussant, MD, MSci15 enrolled1 locationNCT06001749
Not Yet Recruiting
Phase 2
Path-OUD: Psilocybin-Assisted Therapy for people living with Opioid Use Disorder.
Opioid Use Disorder (OUD)
Monash University36 enrolled1 locationACTRN12625001368426
Recruiting
Phase 2
Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication
Chronic PainOpioid Dependence
University of British Columbia10 enrolled1 locationNCT05585229
Recruiting
Phase 1Phase 2
ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain
Chronic PainOpioid Withdrawal
Medical University of South Carolina240 enrolled1 locationNCT06442566
Recruiting
Phase 2
Acetazolamide in Central Sleep Apnea Patients Using Medication for Opioid Use Disorder
Central Sleep Apnea Comorbid With Opioid Use
Sanjay R Patel40 enrolled1 locationNCT06521476
Recruiting
Phase 2
Assessing a Clinically-meaningful Opioid Withdrawal Phenotype
Opioid Withdrawal
University of Maryland, Baltimore60 enrolled1 locationNCT05027919
Recruiting
Phase 1Phase 2
Sleep Disordered Breathing With Opioid Use
Opioid UseSleep Apnea
VA Office of Research and Development150 enrolled1 locationNCT05589753
Recruiting
Phase 2
Lofexidine Combined With Buprenorphine for Reducing Symptoms of PTSD and OU Relapse in Veterans
Post Traumatic Stress DisorderOpioid-use Disorder
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance120 enrolled2 locationsNCT04360681
Recruiting
Phase 2Phase 3
Evaluating Buprenorphine/Naloxone Microdosing vs. Standard Dosing in Emergency Departments
Opioid-use Disorder
University of British Columbia658 enrolled6 locationsNCT04893525
Recruiting
Phase 2Phase 3
Efficacy of Buprenorphine and XR-Naltrexone Combination for Relapse Prevention in Opioid Use Disorder
Opioid-use Disorder
New York State Psychiatric Institute180 enrolled2 locationsNCT05011266
Recruiting
Phase 2Phase 3
Perioperative Analgesia Modes in Minimally Invasive Esophagectomy
Esophageal CancerPerioperative AnalgesiaNSAIDs+2 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences102 enrolled1 locationNCT05504265
Recruiting
Phase 2
Timing of TAP Blocks in Bariatric Surgery
Opioid UsePain, Postoperative
McMaster University100 enrolled1 locationNCT06270147
Recruiting
Phase 2
Anti-retroviral Therapy, Medications for Opioid Use Disorder, Opioids and HIV Infection - Study 1
InflammationHIV-1-infectionOpioid-use Disorder+5 more
University of Pennsylvania225 enrolled2 locationsNCT04480554