plaque Clinical Trials

109 recruitingLast updated: May 11, 2026

There are 109 actively recruiting plaque clinical trials across 44 countries. Studies span Not Applicable, Phase 3, Phase 2, Phase 1, Phase 4, Early Phase 1. Top locations include Beijing, Beijing Municipality, China, Shanghai, Shanghai Municipality, China, Hangzhou, Zhejiang, China. Updated daily from ClinicalTrials.gov.


plaque Trials at a Glance

109 actively recruiting trials for plaque are listed on ClinicalTrialsFinder across 6 cities in 44 countries. The largest study group is Not Applicable with 38 trials, with the heaviest enrollment activity in Beijing, Shanghai, and Hangzhou. Lead sponsors running plaque studies include Bristol-Myers Squibb, Novartis Pharmaceuticals, and Oruka Therapeutics, Inc..

Treatments under study

About plaque Clinical Trials

Looking for clinical trials for plaque? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new plaque trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about plaque clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 109 trials

Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in Children and Adolescents From 6 Years to Less Than 18 Years of Age With Moderate to Severe Plaque Psoriasis

Moderate to Severe Plaque Psoriasis
UCB Biopharma SRL168 enrolled50 locationsNCT06425549
Recruiting
Phase 3

A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque Psoriasis

Plaque Psoriasis
Takeda110 enrolled40 locationsNCT07250802
Recruiting
Phase 3

Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

Plaque Psoriasis
Bristol-Myers Squibb3,040 enrolled357 locationsNCT07116967
Recruiting
Phase 1

A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)

Hidradenitis SuppurativaPsoriatic ArthritisAxial Spondyloarthritis+1 more
UCB Biopharma SRL20 enrolled12 locationsNCT06888193
Recruiting
Phase 3

Targeting Vascular INflammation in Patients With Community-Acquired Pneumonia

InflammationCommunity-Acquired Pneumonia (CAP)Inflammation Plaque, Atherosclerotic
Ottawa Heart Institute Research Corporation168 enrolled1 locationNCT06710080
Recruiting
Not Applicable

Evaluation of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem

Gingival bleedingGingival inflammationDental Plaque
Unilever R&D150 enrolled1 locationNCT07415733
Recruiting

Prospective Carotid Artery Stenosis Trial

Patients With Any Degree of Carotid Artery Stenosis and Vulnerable Features in the Carotid Artery Plaque
Mayo Clinic200 enrolled1 locationNCT05724836
Recruiting
Phase 3

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis
Bristol-Myers Squibb366 enrolled120 locationsNCT06979453
Recruiting
Not Applicable

Modifying PEST for Psoriatic Arthritis Screening

Psoriatic ArthritisPlaque Psoriasis
Novartis Pharmaceuticals502 enrolled21 locationsNCT06382051
Recruiting
Phase 3

A Study to Evaluate the Effect of Bimekizumab on Gene Expression Biomarkers in Study Participants With Moderate to Severe Plaque Psoriasis

Psoriatic ArthritisModerate to Severe Plaque Psoriasis
UCB Biopharma SRL90 enrolled16 locationsNCT06506916
Recruiting
Phase 3

A Clinical Study to Evaluate the Efficacy and Safety of D-2570 in the Treatment of Moderate to Severe Plaque Psoriasis

Plaque Psoriasis
InventisBio Co., Ltd477 enrolled1 locationNCT07326813
Recruiting

Oral Microbiome in Carotid Atherosclerosis

PeriodontitisAtherosclerosis Cardiovascular DiseaseAtherosclerosis of Artery+2 more
Semmelweis University Heart and Vascular Center200 enrolled1 locationNCT07296965
Recruiting
Phase 2

Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis

Plaque Psoriasis
Oruka Therapeutics, Inc.160 enrolled27 locationsNCT07474792
Recruiting

Intraoral Scan and CBCT-Aided Diagnosis of Dental Plaque and Caries

Dental PlaqueDental Caries
University Ghent50 enrolled1 locationNCT07555223
Recruiting
Phase 2

An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis

Plaque Psoriasis
Oruka Therapeutics, Inc.80 enrolled17 locationsNCT07449702
Recruiting

Study to Assess Change in Quality of Life of Risankizumab Treatment in Adult Participants With Moderate-to-Severe Plaque Psoriasis

Plaque Psoriasis
AbbVie700 enrolled70 locationsNCT07039110
Recruiting
Phase 4

Intravascular Imaging Study of the Effect of Inclisiran on Plaque in Patients With Acute Myocardial Infarction

Plaque, Atherosclerotic
Novartis Pharmaceuticals334 enrolled20 locationsNCT06372925
Recruiting
Not Applicable

3D Contrast Enhanced Microvascular Ultrasound of Carotid Atherosclerosis for the Detection of Carotid Plaque Neo-Revascularisation.

Carotid atherosclerosisUltrasoundPlaque Neovascularization
London North West Healthcare NHS Trust10 enrolled1 locationNCT07298655
Recruiting
Not Applicable

Clinical Evaluation of the NeoPill Device for Reduction of Oral Bacterial Load in Patients With Fixed Orthodontic Appliances

Dental Plaque
Neofunction d.o.o.15 enrolled1 locationNCT07355400
Recruiting
Not Applicable

Evaluation of Safety and Efficacy of Bixdo Ultra Compact Water Flosser

Plaque-induced gingivitis
Tufts University165 enrolled1 locationNCT06352645